Protein Alignment ttv and ext1c

DIOPT Version :10

• Sequence 1: NP_001356963.1
• Gene: ttv / 36614
• FlyBaseID: FBgn0265974
• Length: 772
• Species: Drosophila melanogaster
• Sequence 2: NP_001035420.1
• Gene: ext1c / 497281
• ZFINID: ZDB-GENE-050211-5
• Length: 737
• Species: Danio rerio
• Alignment Length: 782
• Identity: 396/782 - (50%)
• Similarity: 518/782 - (66%)
• Gaps: 69/782 - (8%)

  Fly     1 MQAKKRYILV-FVSCAFLAYAYFGGYRLKVSPLRPRRAQHESAKDGGVQP--------HEQLPSF 56
            |||:|:|:|: ..:|.::...|:.|.:.::..|...|.        |..|        ...||:|
Zfish     1 MQARKKYVLLGLCTCCWILLYYWAGLQERLLGLITHRR--------GEVPRPWPDWLDRALLPNF 57

  Fly    57 LGAHDMQELQLLQSN---------QSKSLDSSKHLVTRKPDCRMETCFDFTRCYDR--FLVYIYP 110
            ....|:|       |         |.|...||.:..:|   |||:|||||.||..:  |.|||||
Zfish    58 AEQLDLQ-------NGGGPGDSPRQRKQAWSSIYKDSR---CRMDTCFDFGRCQTQSGFRVYIYP 112

  Fly   111 PEPLNSLGAAPPTSANYQKILTAIQESRYYTSDPTAACLFVLGIDTLDRDSLSEDYVRNVPSRLA 175
            ||      .....|.:|:||||::.|||||||||..||||||||||||||.||:.:|.||..|:.
Zfish   113 PE------KGERVSESYRKILTSVSESRYYTSDPREACLFVLGIDTLDRDQLSQQFVPNVDERIR 171

  Fly   176 RLPYWNNGRNHIIFNLYSGTWPDYAENSLGFDAGEAILAKASMGVLQLRHGFDVSIPLFHKQFPL 240
            ..|.||:||||:||||||||||:|.|: |||:.|:|||||||:.....|.|||:|||||.|:.|.
Zfish   172 GYPLWNDGRNHVIFNLYSGTWPNYTED-LGFNVGQAILAKASLNTEHFRPGFDISIPLFSKEHPQ 235

  Fly   241 RAGATGTVQSNNFPANKKYLLAFKGKRYVHGIGSETRNSLFHLHNGRDMVLVTTCRHGKSWRELQ 305
            :.|..|.:..|:.|..:||||.||||||:.||||:|||:|.|:|||:|:|.:|||||||.|.:.:
Zfish   236 KGGKRGWLVRNSVPPRRKYLLMFKGKRYLTGIGSDTRNALHHIHNGKDIVSLTTCRHGKDWEKHK 300

  Fly   306 DNRCDEDNREYDRYDYETLLQNSTFCLVPRGRRLGSFRFLEALQAGCIPVLLSNAWVLPFESKID 370
            |.|||.||:||:|:||:.||.||||||||||||||||||||:|||.||||||||.|.|||...|.
Zfish   301 DARCDHDNQEYERFDYQELLHNSTFCLVPRGRRLGSFRFLESLQAACIPVLLSNGWELPFSDVIQ 365

  Fly   371 WKQAAIWADERLLLQVPDIVRSIPAERIFALRQQTQVLWERYFGSIEKIVFTTFEIIRERLPDYP 435
            |.||.:..|||||||||..||::..:|:.|||||||.||:.||.|::|||.||.|||::|:..:.
Zfish   366 WNQAVVEGDERLLLQVPSTVRAVGMDRVLALRQQTQTLWDAYFSSVDKIVLTTLEIIKDRVYSHI 430

  Fly   436 VRSSLVWNSSPGALLTLPTFADSSRYMPFLLNSMGAEPRHNYTAVIYVQIGAALGPNAALYKLVR 500
            .|:.|:||:.||.||.||.|:....:.||....:|..|...:||||:. ....:..:..:.||::
Zfish   431 SRNKLMWNALPGGLLVLPEFSTHLAHYPFYYLHLGISPGQEFTAVIHA-TSPLVSQSQPIMKLLQ 494

  Fly   501 TITKSQFVERILVLWAADRPLPLKKRWPPTSHIPLHVISLGGSTRSQGAGPTSQTTEGRPSISQR 565
            .::||::..:|::||.:::..|.:.:|||.. :||.|                  |:||...|.|
Zfish   495 VVSKSKYCSQIIILWNSEKSPPQRSKWPPMP-VPLTV------------------TDGRRKTSSR 540

  Fly   566 FLPYDEIQTDAVLSLDEDAILNTDELDFAYTVWRDFPERIVGYPARAHFWDDSKNAWGYTSKWTN 630
            |||:..|:|:||||||||.:|.|.|::||:.|||.||:||||||.|:||||..|.||||||||||
Zfish   541 FLPHAAIETEAVLSLDEDTVLLTSEINFAFHVWRSFPDRIVGYPPRSHFWDPVKKAWGYTSKWTN 605

  Fly   631 YYSIVLTGAAFYHRYYNYLYTNWLSLLLLKTVQQSSNCEDILMNLLVSHVTRKPPIKVTQRKGYK 695
            .|||:|||||||||||::|::::|...|...|..|.||||||||.|||.||..||:||.|||.||
Zfish   606 EYSIILTGAAFYHRYYHHLFSHYLPSSLRALVDHSCNCEDILMNFLVSSVTHLPPVKVAQRKQYK 670

  Fly   696 D----RETGRSPWNDPDHFIQRQSCLNTFAAVFGYMPLIRSNLRMDPMLYRDPVSNLRKKYRQIE 756
            :    :.|..:||.:|:||.|||.|:|||::.||||||..|..|:||:|::|.||.|||:|:.:|
Zfish   671 EMPSLQGTKMAPWANPEHFTQRQECVNTFSSWFGYMPLEHSQFRLDPVLFKDHVSVLRKRYKDLE 735

  Fly   757 LV 758
            .|
Zfish   736 RV 737

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ttv	NP_001356963.1	Exostosin	102..393	CDD:397245	183/292 (63%)
		Glyco_transf_64	477..737	CDD:430488	130/263 (49%)
ext1c	NP_001035420.1	Exostosin	103..388	CDD:397245	183/291 (63%)
		Glyco_transf_64	472..716	CDD:430488	130/263 (49%)