Protein Alignment ttv and extl3

DIOPT Version :10

• Sequence 1: NP_001356963.1
• Gene: ttv / 36614
• FlyBaseID: FBgn0265974
• Length: 772
• Species: Drosophila melanogaster
• Sequence 2: NP_001008402.1
• Gene: extl3 / 493783
• ZFINID: ZDB-GENE-041124-2
• Length: 917
• Species: Danio rerio
• Alignment Length: 853
• Identity: 235/853 - (27%)
• Similarity: 363/853 - (42%)
• Gaps: 218/853 - (25%)

  Fly    44 DGGVQPHEQLPSFLGAHDMQELQLLQSNQSKSLDSSKHLVTRKPD-----------CRMETCFDF 97
            |...|...||.:.:...:....:|:..||.| |.....|:..|.|           ||:.:|||:
Zfish   115 DSAKQDLLQLKNVISQTEHSYKELMAQNQPK-LSLPVRLLPDKDDPGYPPPKSPQSCRLHSCFDY 178

  Fly    98 TRC--YDRFLVYIYPP------EPLNSLGAAPPTSANYQKILTAIQESRYYTSDPTAACLFVLGI 154
            .||  ...|.||:|..      |.|:.|..        |...::::.|.|.|.:|..|||::..:
Zfish   179 ARCPLTSGFPVYVYDTGSYPWGEKLDPLVK--------QAFASSVKSSVYVTDNPNIACLYIALV 235

  Fly   155 DTLDRDSLSEDYV--RNVPSRLARLPYW-NNGRNHIIFNLYSGTWPDYAENSL------GFDAGE 210
            ..: ::|.|....  .::..:|..|||| ::|.||::.:|        :.|||      ....|.
Zfish   236 GEI-QESPSSPLASPSDLEKQLKALPYWRSDGHNHLLVHL--------SINSLTQNFLYNVSTGR 291

  Fly   211 AILAKASMGVLQLRHGFDVSI-PLFHKQFPLRAGATGTVQSNNF-------PANKKYLLAFKGKR 267
            |.:|:::....|.|.|||:.: ||.|           .:...||       |..:|||..|:|::
Zfish   292 AAVAQSTFFERQYREGFDLVVSPLVH-----------ALSEPNFLEVPPQVPVKRKYLFTFQGEK 345

  Fly   268 YVHGIGSETRNSLF---------------------------------HLHNGRDMVLVT-TCRH- 297
            .     ...|:||.                                 ||    |.|||. ||::
Zfish   346 V-----ESLRSSLLEAPPQSFEEEMEGDPPADYDDRIIGTLKAVQDSHL----DQVLVEFTCKNQ 401

  Fly   298 GKSWRELQDNRCDEDNREYDRYDYETLLQNSTFCLV--PRGRRL-----GSFRFLEALQAGCIPV 355
            .|.....:...|.:      |.|...:|:.|||.||  |...:|     .|.|..|||:.|.|||
Zfish   402 AKPSLPTEWALCGK------REDRLEVLKVSTFALVISPGDGQLVASAGCSMRLFEALEVGAIPV 460

  Fly   356 LLSNAWVLPFESKIDWKQAAIWADERLLLQVPDIVRSIPAERIFALRQQTQVLWERYFGSIEKIV 420
            :|.:...||:...|.|.:|.|...:..:.::..::|||....:.|:|:|.:.|||.||.:.|.|.
Zfish   461 VLGDHSKLPYHHLIRWSEAVIMVPKPRITELHFLLRSISDNDLLAMRRQGRFLWETYFSTSESIF 525

  Fly   421 FTTFEIIRE--RLPDYPVRSS-------------------------------------------- 439
            .|....:|.  ::|..|:|..
Zfish   526 NTILASVRTSIQIPAAPIREEPAQEIPHKAGKLAGTDANLADNGDLDLGPVEVEPPYASPRFLRN 590

  Fly   440 ---------LVWNSSPGALLTLP-TFADSSRYMP----FLLNSMGAEPRHNYTAVIYVQIGAALG 490
                     ..||.:||.....| |..|.  .:|    ||.:..|..|....:.....:..||||
Zfish   591 FTYTAADVYRTWNRAPGPFHLFPHTPLDP--VLPSEAKFLGSGTGFRPIGGGSGGSGKEFQAALG 653

  Fly   491 PNA----------------ALYKLVRTITKSQFVERILVLWAADRPLPLKKRWPPTSHIPLHVIS 539
            .|.                .|...:..:....::.:::|:|.:.:|......||... :|:.|:
Zfish   654 GNVPREQFTVVMLTYEREEVLMNSLERLNGLPYLNKVVVVWNSPKPPSDDLLWPDIG-LPIVVV- 716

  Fly   540 LGGSTRSQGAGPTSQTTEGRPSISQRFLPYDEIQTDAVLSLDEDAILNTDELDFAYTVWRDFPER 604
                            ..|:.|::.||||:|.|:|:|:||:|:||.|..||:.|.:.|||:..:|
Zfish   717 ----------------RTGKNSLNNRFLPWDAIETEAILSIDDDAHLRHDEIMFGFRVWREARDR 765

  Fly   605 IVGYPARAHFWDDSKNAWGYTSKWTNYYSIVLTGAAFYHRYYNYLYTNWLSLLLLKTVQQSSNCE 669
            |||:|.|.|.||.:..:|.|.|.::...|:|||||||:|:||.|||:..:...:...|.:..|||
Zfish   766 IVGFPGRFHAWDLNHQSWLYNSNYSCELSMVLTGAAFFHKYYAYLYSYVMPRAIRDMVDEYINCE 830

  Fly   670 DILMNLLVSHVTRKPPIKVTQRKGYKDRETGRSPWNDPDHFIQRQSCLNTFAAVFGYMPLIRSNL 734
            ||.||.||||:|||||||||.|..::.....::..:|..||.:|..|:|.|..|:|||||:.:..
Zfish   831 DIAMNFLVSHITRKPPIKVTSRWTFRCPGCPQALSHDDSHFHERHKCINFFVKVYGYMPLLYTQF 895

  Fly   735 RMDPMLYR 742
            |:|.:|::
Zfish   896 RVDSVLFK 903

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ttv	NP_001356963.1	Exostosin	102..393	CDD:397245	88/355 (25%)
		Glyco_transf_64	477..737	CDD:430488	97/275 (35%)
extl3	NP_001008402.1	ADIP	<79..>143	CDD:463295	5/27 (19%)
		Exostosin	183..498	CDD:397245	88/357 (25%)
		Glyco_transf_64	661..898	CDD:430488	92/254 (36%)