Protein Alignment ttv and ext2

DIOPT Version :10

• Sequence 1: NP_001356963.1
• Gene: ttv / 36614
• FlyBaseID: FBgn0265974
• Length: 772
• Species: Drosophila melanogaster
• Sequence 2: XP_068078388.1
• Gene: ext2 / 493780
• ZFINID: ZDB-GENE-041124-3
• Length: 736
• Species: Danio rerio
• Alignment Length: 703
• Identity: 254/703 - (36%)
• Similarity: 376/703 - (53%)
• Gaps: 100/703 - (14%)

  Fly    89 CRMETCFDFTRC----YDRFLVYIYPPE--------PLNSLGAAPPTSANYQKILTAIQESRYYT 141
            |||.||||..||    .::..|||||.:        |::|.|    .|..|..:|:||.:|.:||
Zfish   102 CRMHTCFDVYRCGYNPKNKIKVYIYPLQRFVDEVGVPISSTG----LSREYNDLLSAISDSDFYT 162

  Fly   142 SDPTAACLFVLGIDTLDRDSLSEDYVRNVPSRLARLPYWNNGRNHIIFNLYSGTWPDYAENSLGF 206
            .|.:.|||||..||.|:::||.   :|.....||.||.|:.|.||::||:..|..||| ..:|..
Zfish   163 DDVSRACLFVPSIDVLNQNSLR---IRETAQALAMLPRWDKGMNHLLFNMLPGGPPDY-NTALDV 223

  Fly   207 DAGEAILAKASMGVLQLRHGFDVSIPLFHKQFPLRAGATGTVQSNNFPANKKYLLAFKGKRYVHG 271
            ....|:||.........|.|:|||||::.   ||.|...   .....|..::|.: ...:..:|
Zfish   224 PRDRALLAGGGFSTWTYRQGYDVSIPVYS---PLSAEVD---LPERQPGPRRYFI-LSSQTAIH- 280

  Fly   272 IGSETRNSLFHL--HNGRDMVLVTTCRHGKSWRELQDNRCDEDNREYDRYDYETLLQNSTFCLVP 334
              .|.|..|..|  .||..::|:..|.:..........||.:.    ..|||..:||.|:||:|.
Zfish   281 --REYRVELERLKDENGEALLLLDKCSNLSQGLTSVRKRCYKG----QVYDYPQILQESSFCVVL 339

  Fly   335 RGRRLGSFRFLEALQAGCIPVLLSNAWVLPFESKIDWKQAAIWADERLLLQVPDIVRSIPAERIF 399
            ||.|||.....:.|||||:||:::::::|||...:|||:|::...|..|.::..|::|||..::.
Zfish   340 RGARLGQATLSDVLQAGCVPVIMADSYILPFSEVLDWKRASVVIPEEKLPEMYTILKSIPHRQVE 404

  Fly   400 ALRQQTQVLWERYFGSIEKIVFTTFEIIRERLPDYPVRSSLVWNSSPGALLTLPTFADSSRYMPF 464
            .:::|.:..||.||.|::.|..||.:||.:|:..|...:...||:.|   :...:..:|..::|.
Zfish   405 EMQRQARWFWEAYFSSMKAIGMTTLQIINDRIYPYAAHTYEEWNNPP---VVKWSSVNSPLFLPL 466

  Fly   465 LLNSMGAEPRH-NYTAVI--YVQIGAALGPNAALYKLVRTITKSQFVERILVLW-AADRPLPLKK 525
            :      .||. .:|||:  |.:|       .:|::::..|:|...:.::||:| ..::..|.:.
Zfish   467 I------PPRSPGFTAVVLTYDRI-------ESLFRVITEISKVPSLAKLLVVWNNQNKSPPEES 518

  Fly   526 RWPPTSHIPLHVISLGGSTRSQGAGPTSQTTEGRPSISQRFLPYDEIQTDAVLSLDEDAI-LNTD 589
            .||..: :||.|:               :|.|.:  :|.||.|:|||:|:|||::|:|.| |.:|
Zfish   519 LWPKVA-VPLKVV---------------RTKENK--LSNRFFPFDEIETEAVLAIDDDIIMLTSD 565

  Fly   590 ELDFAYTVWRDFPERIVGYPARAHFWDDSKNAWGYTSKWTNYYSIVLTGAAFYHRYYNYLYT--- 651
            ||.|.|.|||:||:|:||||.|.|.||.....|.|.|:|||..|:|||||||||:|:|||||
Zfish   566 ELQFGYEVWREFPDRLVGYPGRLHLWDHEMGKWKYESEWTNEVSMVLTGAAFYHKYFNYLYTYKM 630

  Fly   652 -----NWLSLLLLKTVQQSSNCEDILMNLLVSHVTRKPPIKVTQRKGYKDRE----TGRSPWNDP 707
                 ||        |....|||||.||.||:::|.|.|||||.||.:|..|    .|.|  .|.
Zfish   631 PGDIKNW--------VDAHMNCEDIAMNFLVANITGKAPIKVTPRKKFKCPECTAIDGLS--LDQ 685

  Fly   708 DHFIQRQSCLNTFAAVFGYMPLIRSNLRMDPMLYRDPVSNLRKKYRQIELVGS 760
            .|.::|..|:|.||:|||.|||.....|.||:||:|   :..:|.:....:||
Zfish   686 THMVERSECINKFASVFGTMPLKVVEHRADPVLYKD---DFPEKLKSFPNIGS 735

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ttv	NP_001356963.1	Exostosin	102..393	CDD:397245	100/300 (33%)
		Glyco_transf_64	477..737	CDD:430488	114/275 (41%)
ext2	XP_068078388.1	Exostosin	117..398	CDD:397245	100/302 (33%)
		Glyco_transf_64	474..715	CDD:430488	114/275 (41%)