Protein Alignment Arc1 and Arc

DIOPT Version :10

• Sequence 1: NP_610955.1
• Gene: Arc1 / 36595
• FlyBaseID: FBgn0033926
• Length: 254
• Species: Drosophila melanogaster
• Sequence 2: NP_062234.2
• Gene: Arc / 54323
• RGDID: 62037
• Length: 396
• Species: Rattus norvegicus
• Alignment Length: 216
• Identity: 50/216 - (23%)
• Similarity: 80/216 - (37%)
• Gaps: 23/216 - (10%)

  Fly    23 AVGAAGSAAAAGGADASRGKGNFSACTHSFGGTRDHDVVEEFIGNIETYKDVEGISDENALKGIS 87
            :|||....:...|.|.....|   ..|..|...|      ||:.::|.|....|.|:|..|..|.
  Rat   188 SVGAQQYQSWVPGEDGQPSPG---VDTQIFEDPR------EFLSHLEEYLRQVGGSEEYWLSQIQ 243

  Fly    88 LLFYGMASTWWQGVRKEATTWKEAIALIREHFSPTKPAYQIYMEFFQNKQDDHDPIDTFVIQKRA 152
            ....|.|..||:..:.....|.|......::...|.....|..| ....|...:|:|.|:.:||.
  Rat   244 NHMNGPAKKWWEFKQGSVKNWVEFKKEFLQYSEGTLSREAIQRE-LDLPQKQGEPLDQFLWRKRD 307

  Fly   153 LLAQLPSGRHDEETELDLLFGLLNIKYRKHISRHSVHTFKDLLEQGRIIEHNNQ----------- 206
            |...|.....:||. :..:.|.|..|:::.:......|.:.|:::|..::...:
  Rat   308 LYQTLYVDAEEEEI-IQYVVGTLQPKFKRFLRHPLPKTLEQLIQRGMEVQDGLEQAAEPSVTPLP 371

  Fly   207 -EDEEQLATAKNTRGSKRTTR 226
             |||.:..|...|..|..:.|
  Rat   372 TEDETEALTPALTSESVASDR 392

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Arc1	NP_610955.1	None
Arc	NP_062234.2	Arc_MA	46..154	CDD:437116
		Interaction with SH3GL1 or SH3GL3. /evidence=ECO:0000269|PubMed:17088211	89..100
		Interaction with DNM2. /evidence=ECO:0000269|PubMed:17088211	195..214		4/21 (19%)
		Arc_C	278..355	CDD:465670	19/78 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	358..396		7/35 (20%)