Protein Alignment Arc1 and Arc

DIOPT Version :10

• Sequence 1: NP_610955.1
• Gene: Arc1 / 36595
• FlyBaseID: FBgn0033926
• Length: 254
• Species: Drosophila melanogaster
• Sequence 2: NP_061260.1
• Gene: Arc / 11838
• MGIID: 88067
• Length: 396
• Species: Mus musculus
• Alignment Length: 212
• Identity: 49/212 - (23%)
• Similarity: 82/212 - (38%)
• Gaps: 35/212 - (16%)

  Fly    13 RELIEAVRAAAVGAAGSAAAAGGADASRGKGNFSACTHSFGGTRDHDVVEEFIGNIETYKDVEGI 77
            :|.:||.:..:.|.......:.|.|           |..|...|      ||:.::|.|....|.
Mouse   186 QESVEAQQYQSWGPGEDGQPSPGVD-----------TQIFEDPR------EFLSHLEEYLRQVGG 233

  Fly    78 SDENALKGISLLFYGMASTWWQGVRKEATTWKEAIALIREHF------SPTKPAYQIYMEFFQNK 136
            |:|..|..|.....|.|..||:..:.....|.|    .::.|      :.::.|.|..:|.   .
Mouse   234 SEEYWLSQIQNHMNGPAKKWWEFKQGSVKNWVE----FKKEFLQYSEGTLSREAIQRELEL---P 291

  Fly   137 QDDHDPIDTFVIQKRALLAQLPSGRHDEETELDLLFGLLNIKYRKHISRHSVHTFKDLLEQGRII 201
            |...:|:|.|:.:||.|...|.....:||. :..:.|.|..|.::.:......|.:.|:::|..:
Mouse   292 QKQGEPLDQFLWRKRDLYQTLYVDAEEEEI-IQYVVGTLQPKLKRFLRHPLPKTLEQLIQRGMEV 355

  Fly   202 EHNNQEDEEQLATAKNT 218
                |:..||.|....|
Mouse   356 ----QDGLEQAAEPSGT 368

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Arc1	NP_610955.1	None
Arc	NP_061260.1	Arc_MA	46..154	CDD:437116
		Interaction with SH3GL1 or SH3GL3. /evidence=ECO:0000250|UniProtKB:Q63053	89..100
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	177..207		4/20 (20%)
		Interaction with DNM2. /evidence=ECO:0000250|UniProtKB:Q63053	195..214		4/29 (14%)
		Arc_C	278..355	CDD:465670	19/80 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	356..396		5/13 (38%)