DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment tej and Snd1

DIOPT Version :9

Sequence 1:	NP_610950.2	Gene:	tej / 36590	FlyBaseID:	FBgn0033921	Length:	559	Species:	Drosophila melanogaster
Sequence 2:	NP_062750.2	Gene:	Snd1 / 56463	MGIID:	1929266	Length:	910	Species:	Mus musculus

Alignment Length:	410	Identity:	75/410 - (18%)
Similarity:	141/410 - (34%)	Gaps:	108/410 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 DDGGELSLVKKVVHSLVVSSPGKLTVEQL-----MRDYRSEEGCTLPYSKLGFKDAESFLRSIPD 61
            |..|:....|:.:..|..:...:..||.:     ::.|..:|.|.:.:...|. :.....|::|.
Mouse   506 DISGDTQKAKQFLPFLQRAGRSEAVVEYVFSGSRLKLYLPKETCLITFLLAGI-ECPRGARNLPG 569

  Fly    62 TVTVTGHGQMAWITAVATAKSAHIQKLVRCQKKSKNRGSHKPKYCYASEPSNL--VFINESVSKM 124
            .|.   .|:.....|....|...:|:.|..:.:|.::..:...:.: .:.:||  :.:.:::||
Mouse   570 LVQ---EGEPFSEEATLFTKELVLQREVEVEVESMDKAGNFIGWLH-MDGANLSVLLVEQALSK- 629

  Fly   125 KNRKAPFPTYQVPRNLKLPVSYPNYNRLLYPVHTPHIDQMISTGQQQSTLRTQRPSFPCNANSKS 189
                                           ||        .|.::.:   ..:|.......:|.
Mouse   630 -------------------------------VH--------FTAERSA---YYKPLLSAEEAAKQ 652

  Fly   190 LKVNDWSQ-KDRKQE------PSKERNNQKYPKITTE-------NKQEKET-EELAQAFENLSVD 239
            .|...|:. ::|..|      ..|||:....|...||       ..|:.|| .:|.:..||:..|
Mouse   653 RKEKVWAHYEERPVEEVMPVLEEKERSASYKPVFVTEITDDLHFYVQDVETGTQLEKLMENMRND 717

  Fly   240 VA---PTDHQEKLKCEIYEDNEDEFVRDPFIYGE-----VKEKEDEAVVLAFDAVSEDGFDLLSM 296
            ::   |.:..       |.....||....|:.||     |::.|..|.|..| .:.....::|
Mouse   718 ISSHPPVEGS-------YAPRRGEFCIAKFVDGEWYRARVEKVESPAKVHVF-YIDYGNREIL-- 772

  Fly   297 TTTQQNAVKPLDPPEDCLHYASSDDGEDENAIPAYAVDHRVLDVDYPR--DAVRSAFTLPARDIE 359
            .:|:...:.|               ......:||.|.::....:..|:  ||...|.....|||:
Mouse   773 PSTRLGTLPP---------------AFSTRVLPAQATEYAFAFIQVPQDEDARTDAVDSVVRDIQ 822

  Fly   360 SIIELQQRIRVQLVSLVNPH 379
            :   .|..:.|:.:|...||
Mouse   823 N---TQCLLNVEHLSASCPH 839

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tej	NP_610950.2	LOTUS_TDRD_OSKAR	7..93	CDD:193586	16/90 (18%)
tej	NP_610950.2	TUDOR	379..488	CDD:278965	1/1 (100%)
Snd1	NP_062750.2	SNc	21..166	CDD:214615
		SNc	26..166	CDD:238102
		SNc	193..328	CDD:214615
		SNc	201..328	CDD:238102
		Nuclear localization signal. /evidence=ECO:0000255	321..325
		SNc	341..495	CDD:214615
		SNc	350..496	CDD:238102
		Nuclear localization signal. /evidence=ECO:0000255	388..392
		SNc	525..660	CDD:214615	26/182 (14%)
		SNc	533..660	CDD:238102	24/174 (14%)
		TUDOR	677..799	CDD:278965	30/146 (21%)
		TUDOR	728..784	CDD:197660	14/73 (19%)
		SNc	<844..895	CDD:294094
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1525
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810