DRSC/TRiP Functional Genomics Resources

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Protein Alignment: tej and TDRD6

Sequence 1:NP_610950.2 Gene:tej FlyBaseID:FBgn0033921 Length:559 Species:Drosophila melanogaster
Sequence 2:NP_001010870.1 Gene:TDRD6 HGNCID:21339 Length:2096 Species:Homo sapiens

Alignment Length:599 Identity:116/600 (19%)
Similarity:210/600 (35%) Gaps:174/600 (29%)


  Fly     6 ELSLVKKVVHSLVVSSPGKLTVEQLMRDYRSEEGCTLP-YSKLGFKDAESFLRSIPDTVTVTGHG 69
            ||.|.::|..||..|     .:|:.:....:..|..:| .|::..|..:..|......:      
Human   193 ELGLARRVPDSLFRS-----LLERYLTAATASVGSGVPVLSRVPLKQKQPGLDYFYPQL------ 246

  Fly    70 QMAWITAVATAKSAHIQKLVRCQKKSKNRGSHKPKYCYASEPSNLVFINESVSKMKNRKAPFPTY 134
            |:....||...:..|..: :.||.:|.::..|:              ::||::            
Human   247 QLGVTEAVVITQVCHPHR-IHCQLRSVSQEIHR--------------LSESMA------------ 284

  Fly   135 QVPRNLKLPVSYPNYNRLLYPVHTPHIDQMISTGQQQSTLRTQRPSFPCNANSKSLKVNDWSQKD 199
            ||.|.                        ...||.:.||..|                  |  ::
Human   285 QVYRG------------------------STGTGDENSTSAT------------------W--EE 305

  Fly   200 RKQEPSKE--------RNNQKYPKITTENKQEKETEELAQAFENLSVDVAPTDHQEKLKCEIYED 256
            |::.|.|.        .:...|..:..|..:.:...::      |.||..   .:|.:.|.....
Human   306 REESPDKPGSPCASCGLDGHWYRALLLETFRPQRCAQV------LHVDYG---RKELVSCSSLRY 361

  Fly   257 NEDEFVRDPFI--------------------YGEVKE----KEDEAVV---LAFDAV------SE 288
            ...|:.|.|.:                    .|::|.    |...|.:   .:|:.|      .|
Human   362 LLPEYFRMPVVTYPCALYGLWDGGRGWSRSQVGDLKTLILGKAVNAKIEFYCSFEHVYYVSLYGE 426

  Fly   289 DGFDLLSMTTTQQNAVKPLDPPEDCLHYASSDDGEDENA---IPAYAVDHRVLDVDYPRDAVRSA 350
            ||.:|..:...|...:     .:..|...::::.|.|.:   .||..||..:             
Human   427 DGINLNRVFGVQSCCL-----ADRVLQSQATEEEEPETSQSQSPAEEVDEEI------------- 473

  Fly   351 FTLPARDIESI-IELQQRIRVQLVSLVNPHNFNFWIYNDDFKDYEAQFANMQT----FYESSESK 410
             :|||  :.|| :::......|:..:.||.  .|||   ..:.:...|:.:..    || ||.||
Human   474 -SLPA--LRSIRLKMNAFYDAQVEFVKNPS--EFWI---RLRKHNVTFSKLMRRMCGFY-SSASK 529

  Fly   411 NYTMPLFLITTDHLCVVRCTSGWERAKVLGYRSSNNKMTIEVELVDIGDIIRVSQQNVKFLIKPF 475
            ...:.|.....|..||....:|:.||.|    :..:..:::|.|||.|:...|...:|:.|:..|
Human   530 LDGVVLKPEPDDLCCVKWKENGYYRAIV----TKLDDKSVDVFLVDRGNSENVDWYDVRMLLPQF 590

  Fly   476 ALLPRQCLAGRLAFITQCKSPNWTAEVVNFFHDMILLRLLYAKVEAIKNNTAYLVLVDTESQGHT 540
            ..||...:...||.|... ...|:.|.|:||...:|.:.|...: ..|.:..|::.:..||:...
Human   591 RQLPILAVKCTLADIWPL-GKTWSQEAVSFFKKTVLHKELVIHI-LDKQDHQYVIEILDESRTGE 653

  Fly   541 VNLNRSLIETGWVR 554
            .|:::.:.:.|:.:
Human   654 ENISKVIAQAGYAK 667

Known Domains:


GeneSequenceDomainRegion External IDIdentity
tejNP_610950.2 LOTUS_TDRD_OSKAR 7..93 CDD:193586 18/87 (21%)
TUDOR 379..488 CDD:278965 30/113 (27%)
TDRD6NP_001010870.1 TUDOR <69..133 CDD:278965
TUDOR 246..380 CDD:278965 32/220 (15%)
TUDOR 314..360 CDD:119391 7/55 (13%)
TUDOR 483..604 CDD:278965 34/131 (26%)
TUDOR 541..585 CDD:119391 14/48 (29%)
TUDOR 770..886 CDD:278965
TUDOR 821..866 CDD:119391
TUDOR 982..1102 CDD:278965
TUDOR 1037..1080 CDD:119391
TUDOR 1301..1422 CDD:278965
TUDOR 1356..1401 CDD:119391
TUDOR 1516..1638 CDD:278965
TUDOR 1571..>1609 CDD:119391
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
eggNOG 1 0.900 E1_COG1525
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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