Protein Alignment Mdr50 and cydD

DIOPT Version :10

• Sequence 1: NP_523740.3
• Gene: Mdr50 / 36582
• FlyBaseID: FBgn0010241
• Length: 1313
• Species: Drosophila melanogaster
• Sequence 2: NP_415407.1
• Gene: cydD / 949052
• ECOCYCID: EG11405
• Length: 588
• Species: Escherichia coli
• Alignment Length: 511
• Identity: 148/511 - (28%)
• Similarity: 233/511 - (45%)
• Gaps: 54/511 - (10%)

  Fly   170 YAAHSQI-LTIRSKFFRSILHQDMKWYDFNQSGEVASRMNEDLSKMED---------GLAEKVVM 224
            |.|...| ..||.:....:......|.....:|..|:.:.|.:..|.|         .||..|.:
E. coli    88 YHAGQHIRFAIRRQVLDRLQQAGPAWIQGKPAGSWATLVLEQIDDMHDYYARYLPQMALAVSVPL 152

  Fly   225 FVHYLVAFVGSLVLAFVKGWQLSLVCLTSLPLTFIAMGLVAVATSRLAKKEVTMYAGAAVVAEGA 289
            .:         :|..|...|..:|:.|.:.||..:.|.||.:..:...::.....|..:......
E. coli   153 LI---------VVAIFPSNWAAALILLGTAPLIPLFMALVGMGAADANRRNFLALARLSGHFLDR 208

  Fly   290 LSGIRTVKAF---EGEAKEVAAYKERVVAAKILNIKRNMFSGIGFGLLWFFIYASYAL-AFWYGV 350
            |.|:.|::.|   |.|.:.:.:..|. ...:.:.:.|..|  :..|:|.||...|.|| |.::|.
E. coli   209 LRGMETLRIFGRGEAEIESIRSASED-FRQRTMEVLRLAF--LSSGILEFFTSLSIALVAVYFGF 270

  Fly   351 GLVIKGYHEPAYENYDAGTMITVFFSVMMGSMNIGMAAP-----------YIEAFGIAKGACAKV 404
            ..:    .|..:.:||.|..:...|..:       :.||           :..|...|.||...:
E. coli   271 SYL----GELDFGHYDTGVTLAAGFLAL-------ILAPEFFQPLRDLGTFYHAKAQAVGAADSL 324

  Fly   405 FHIIEQIPEINPIDGEGKKLNEPLTTIEFKEVEFQYPTRPE-VSILNKLNLKIHRGQTVALVGPS 468
            ...:| .|..:|..||.:..:....|||.:|:   :.|.|| .::...||..:..||...|||.|
E. coli   325 KTFME-TPLAHPQRGEAELASTDPVTIEAEEL---FITSPEGKTLAGPLNFTLPAGQRAVLVGRS 385

  Fly   469 GCGKSTCIQLVQRFYDPQAGNLLFNGTNLKDLDINWLRSRIGVVGQEPILFATSIYENIRYGRED 533
            |.|||:.:..:..|...| |:|..||..|:||.....|..:..|||.|.|.|.::.:|:...|.|
E. coli   386 GSGKSSLLNALSGFLSYQ-GSLRINGIELRDLSPESWRKHLSWVGQNPQLPAATLRDNVLLARPD 449

  Fly   534 ATREEIEAAAAAANAAIFIKKLPKGYDTLVGERGAQLSGGQKQRIAIARALIRDPEILLLDEATS 598
            |:.:|::||...|..:.|:..||:|.||.||::.|:||.||.||:|:||||:....:|||||..:
E. coli   450 ASEQELQAALDNAWVSEFLPLLPQGVDTPVGDQAARLSVGQAQRVAVARALLNPCSLLLLDEPAA 514

  Fly   599 ALDTASEAKVQAALEKVSAGRTTIIVAHRLSTVRRADRIVVINKGEVVESGTHQEL 654
            :||..||.:|..||...|..:||::|.|:|..:...|.|.|:..|.::|.|.:.||
E. coli   515 SLDAHSEQRVMEALNAASLRQTTLMVTHQLEDLADWDVIWVMQDGRIIEQGRYAEL 570

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mdr50	NP_523740.3	PTZ00265	69..1308	CDD:240339	148/511 (29%)
cydD	NP_415407.1	PRK11174	1..588	CDD:236870	148/511 (29%)