Protein Alignment Mdr50 and tap2t

DIOPT Version :10

• Sequence 1: NP_523740.3
• Gene: Mdr50 / 36582
• FlyBaseID: FBgn0010241
• Length: 1313
• Species: Drosophila melanogaster
• Sequence 2: XP_005156356.1
• Gene: tap2t / 556826
• ZFINID: ZDB-GENE-130531-48
• Length: 728
• Species: Danio rerio
• Alignment Length: 610
• Identity: 189/610 - (30%)
• Similarity: 308/610 - (50%)
• Gaps: 78/610 - (12%)

  Fly   120 GGLLESGKSYRADDAISTLLLDKVRQFSLQNTYIG------------------------------ 154
            ||..:.|::.:.|:....||:..:|...|...|:|
Zfish   134 GGSSKGGRNQKKDEEARALLMRVIRYSRLDYLYLGAAFIFLSLAALFETFIPYCTGKVIDILSGK 198

  Fly   155 ----------IIMLVCSY-------LSITCFNYAAHSQILTIRSKFFRSILHQDMKWYDFNQSGE 202
                      :::.:||.       |....|.::.:.....||:..|::::.|::.::|..:.|.
Zfish   199 YQHSNFTWAILLLALCSLGSSMFSGLRGGMFMFSLNRLNKRIRNLLFQNVMKQEIDFFDEIKPGN 263

  Fly   203 VASRMNEDLSKMEDGLAEKVVMFVHYLVAFVGSLVLAFVKGWQLSLVCLTSLPLTFIAMGLVAVA 267
            :|||:..|..||...:|..|.:.:..:|...|.|.......|||:|:....:||...........
Zfish   264 LASRLISDTDKMGRAVAMNVNVLLRSMVKTCGMLYFMLGVSWQLTLLTCIEMPLLAFLQNSYNSL 328

  Fly   268 TSRLAKKEVTMYAGAAVVAEGALSGIRTVKAFEGEAKEVAAYKERVVAAKILNIKRNMFSGIGFG 332
            :.:.:|:.....|....:|...:..|:||::|:.|.:|...| |:.:..|:..::|..|....:.
Zfish   329 SQKTSKELQDCNAETGELASSVIGSIKTVRSFKAECQEQQRY-EQTINRKLQVLRRKGFYSAVYL 392

  Fly   333 LLWFFIYASYALA-FWYGVGLVIKGYHEPAYENYDAGTMIT-VFFSV-MMGSMNIGMAAPYIEAF 394
            |:..||.....:| ...|..|:..|       ...:|:::. ||:.. |:.||.     ..:..:
Zfish   393 LIRRFITVGLKVAMLCQGRNLISSG-------QLSSGSLLAFVFYQKDMVTSMK-----HLVYIY 445

  Fly   395 G---IAKGACAKVFHIIEQIPEINPI-DGEGKKLNEPLTTIEFKEVEFQYPTRPEVSILNKLNLK 455
            |   ...|:..|||.::::.|::... |...:||...:|   |::|.|.|.:||:.:.|..:.|:
Zfish   446 GDMLSTVGSSVKVFQLLDRKPQMREAGDLAPEKLKGRIT---FEKVTFSYLSRPDDTALKSVTLE 507

  Fly   456 IHRGQTVALVGPSGCGKSTCIQLVQRFYDPQAGNLLFNGTNLKDLDINWLRSRIGVVGQEPILFA 520
            :..|:..|||||||.|||:|:.|:||||:|:.|.:..:|..|......:|..::.||.|:|:||:
Zfish   508 LSPGKLTALVGPSGGGKSSCVSLLQRFYEPKEGEMFLDGEPLYHYQHQYLHKKVAVVSQDPVLFS 572

  Fly   521 TSIYENIRYGREDATREEIEAAAAAANAAIFIKKLPKGYDTLVGERGAQLSGGQKQRIAIARALI 585
            .|:..||.||.:|.|.|.||.||..|||..||..|.:||||.|||.|.|||.||||.||||||||
Zfish   573 GSVRYNIEYGLQDCTLERIEEAARKANAHNFICNLEQGYDTDVGECGGQLSAGQKQCIAIARALI 637

  Fly   586 RDPEILLLDEATSALDTASEAKVQAALEKVSAGRTTIIVAHRLSTVRRADRIVVINKGEVVESGT 650
            |:|:||:||||||.:|::::..:|..|..:: .:|.:::||||.|:.:||.|:.:..|||.|.||
Zfish   638 RNPQILILDEATSHMDSSTQQAIQDVLNSIT-DQTVLVIAHRLETIEKADHIIFMEGGEVKEQGT 701

  Fly   651 HQELME-------LKDHYFNLVTTQ 668
            ||:||:       |::..|||.|.|
Zfish   702 HQQLMDKQGRYHRLREKLFNLETQQ 726

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mdr50	NP_523740.3	PTZ00265	69..1308	CDD:240339	189/610 (31%)
tap2t	XP_005156356.1	3a01208	28..715	CDD:273363	183/597 (31%)