Protein Alignment Mdr50 and tap1

DIOPT Version :10

• Sequence 1: NP_523740.3
• Gene: Mdr50 / 36582
• FlyBaseID: FBgn0010241
• Length: 1313
• Species: Drosophila melanogaster
• Sequence 2: XP_002665053.1
• Gene: tap1 / 100333043
• ZFINID: ZDB-GENE-050517-43
• Length: 731
• Species: Danio rerio
• Alignment Length: 541
• Identity: 185/541 - (34%)
• Similarity: 292/541 - (53%)
• Gaps: 55/541 - (10%)

  Fly   151 TYIGIIMLVCSYLSITCFNYAAHSQILTIRSKFFRSILHQDMKWYDFNQSGEVASRMNEDLSKME 215
            |.:.|:..||.::....:|........:|:...|:::|.||:.::|...:|::.||:..|.:.|.
Zfish   207 TLMTIMSAVCEFVCDLIYNITMSRIHTSIQGLVFQAVLKQDIAFFDKATTGDIVSRITTDTNTMS 271

  Fly   216 DGLAEKVVMFVHYLVAFV---GSLVLAFVKGWQLSLVCLT--SLPLTFIAMGLVAVATSRLAKKE 275
            :.|:||:.:.:.|.:..:   ||:::...:     |.|.|  .||:.:|...:......:|:.:.
Zfish   272 ESLSEKLSLLMWYFMRVIFLFGSMLMLSTR-----LCCFTLLGLPVIWIIPEIFGRFYQKLSAQV 331

  Fly   276 VTMYAGAAVVAEGALSGIRTVKAFEGEAKEVAAYKERVVAAKILNIKRNMFSGIGFGLLWFFIYA 340
            ....|.|..||....|.::||::|..|..|...|::.:.....||...               .|
Zfish   332 QDSLAKANEVATETFSSMKTVRSFANEDGETERYRKCLEDTFALNKVE---------------AA 381

  Fly   341 SYALAFW---------------YGVGLVIKGYHEPAYENYDAGTMITVFFSVMMGSMNIGMAAPY 390
            :||::.|               || |.::.|      .:..:|.:::.....:..:..:.:...|
Zfish   382 AYAVSTWTNSMSSLALKVSILYYG-GRLVTG------SDVSSGDLVSFVLYELQFTSAVEVLMSY 439

  Fly   391 IEAFGIAKGACAKVFHIIEQIPEINPIDGEGKKLNEPLTT---IEFKEVEFQYPTRPEVSILNKL 452
            ......|.||..|:|..:::.|::.| ||.    ..|.|.   ::|:.|.|.||.||:..:|..:
Zfish   440 WPHVKKAVGASEKIFEYVDRKPDVPP-DGS----LAPKTLKGHVQFRNVTFAYPKRPDTDVLKNV 499

  Fly   453 NLKIHRGQTVALVGPSGCGKSTCIQLVQRFYDPQAGNLLFNGTNLKDLDINWLRSRIGVVGQEPI 517
            :|::..|:..|||||||.||:|.:.|::|||.||.|.:|.:...|......:|..:|.||.|||:
Zfish   500 SLELKAGKITALVGPSGSGKTTVVSLLERFYQPQNGEILLDQKPLLSYKDQYLHEKISVVSQEPV 564

  Fly   518 LFATSIYENIRYGREDATREEIEAAAAAANAAIFIKKLPKGYDTLVGERGAQLSGGQKQRIAIAR 582
            |||.|:.|||:||:|:||.|||.|||..|||..||..|||||||..||:|.|:||||||||||||
Zfish   565 LFARSVRENIKYGKENATNEEIYAAARLANAHDFISSLPKGYDTDAGEKGGQVSGGQKQRIAIAR 629

  Fly   583 ALIRDPEILLLDEATSALDTASEAKVQAALEKVSAGRTTIIVAHRLSTVRRADRIVVINKGEVVE 647
            |||:.|:||:||:|||:|||.||.:|.:||:|.....|.::::||||.|..||.|:.:.:||:||
Zfish   630 ALIQKPQILVLDDATSSLDTESEHRVYSALKKELQSCTVLLISHRLSGVENADHILFLREGELVE 694

  Fly   648 SGTHQELMELKDHYFNLVTTQ 668
            .|.||:|::.:..|...|..|
Zfish   695 EGNHQQLLDKQGFYAEFVKQQ 715

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mdr50	NP_523740.3	PTZ00265	69..1308	CDD:240339	185/541 (34%)
tap1	XP_002665053.1	3a01208	42..712	CDD:273363	183/536 (34%)