Protein Alignment CG8468 and slc16a5a

DIOPT Version :10

• Sequence 1: NP_610940.1
• Gene: CG8468 / 36577
• FlyBaseID: FBgn0033913
• Length: 678
• Species: Drosophila melanogaster
• Sequence 2: XP_021336012.1
• Gene: slc16a5a / 565514
• ZFINID: ZDB-GENE-121108-4
• Length: 506
• Species: Danio rerio
• Alignment Length: 684
• Identity: 137/684 - (20%)
• Similarity: 238/684 - (34%)
• Gaps: 221/684 - (32%)

  Fly     1 MATQQTKSQDELASKGLVSKQPENIKEENEGEEEIEEAAVVVP-----PDSGWAWVVMVASFLCC 60
            ||.||..|.:|.:.: |...:.|.::::..|......|    |     ||.||.|||::|:.:..
Zfish     1 MAPQQPSSMEEQSGE-LCEPESEELEKQGPGPPSNANA----PDSYDAPDGGWGWVVLLATIIVL 60

  Fly    61 TVIDGIVFCSGLIQEQLMAEFGVSKAYVAFVSSLLSGCYLMAGPFVSAMANRFGFRPVTITGAIF 125
            .:......|..:....|..||..:.:..::|.|:::......||..|.:.:|||.|...:.|.:.
Zfish    61 ALTLAFPSCIIIFYLDLQKEFEATNSQTSWVPSIMTAVLHAGGPLCSVLVDRFGCRATVMFGGVL 125

  Fly   126 AAICFGLSYFATSVEYLFLIYGVLGGIGFCMVYIPAVVIIGFYFEKWRALATGVAMCGSGVGTFV 190
            :.....:|.|:.|:..|::..||:.|:|||..:.|||.|:|.||.:.|..|..::..|:.:|...
Zfish   126 SGFGMAVSSFSHSIVDLYITAGVITGLGFCFSFQPAVTILGHYFVRRRPFANAMSSTGTALGLST 190

  Fly   191 FAPLTKIL-LKSGWRYTLAIQGIIVLSCALFGLAFRPIQPITLSVTNEEGDEQEKKKLNGHGNTV 254
            ...|...| ::.|||.:..:.|.::|:|.:.|...|||:|            ::.:|.|...|:
Zfish   191 LPFLCDFLKIELGWRGSFLVLGAVLLNCCVCGAVMRPIRP------------RKPRKTNEINNS- 242

  Fly   255 APTPQLHQAAFTKPLPEGRFAYSMPNSAHNTYMGASQRNHYPTAQEIFKGMNLERRPSGTAQGSK 319
                                    |.::..                  ||..|     |..| |.
Zfish   243 ------------------------PKTSDK------------------KGCML-----GICQ-SL 259

  Fly   320 GTELKQLRKSQPTTPNGDPQQLTFNLHKELTTVGENEEEAENDNLLETEAKPVTIQARRHTVSGR 384
            .:.|:              ||:.|
Zfish   260 ASSLR--------------QQMAF----------------------------------------- 269

  Fly   385 RPQDIGKRSAAAAHEAHHGQSHSSSRPMYRDDIFFSGSLTRIPQYQSQTSLAYHMSVTRLPTKQD 449
                                           |:|.|.:..|:          :.:.:|.:
Zfish   270 -------------------------------DLFCSNTRFRV----------FSLGITWM----- 288

  Fly   450 MLEDRQKGCRICPEAVRRTLSTMLDTTLLKSPAFMCLAFSGFLTMMGFFVPFTFLVDRAKAAGMD 514
                                                        |:||.||..:||..|.|..||
Zfish   289 --------------------------------------------MLGFVVPLIYLVPYASADDMD 309

  Fly   515 EQAAYGVLSGIGVVNTFARIVCGSLSSFPAVK--PLWLNNFALTAGGIATICSGIVINTATQWTF 577
            ...|..:||.:|.||.|.|...|.|.|.|..|  .:::.:.||...|::.....|..:......:
Zfish   310 PSRAALLLSILGFVNIFVRPPVGVLFSLPWFKGRHIYVFSAALLINGLSNSICCISASFPVLLVY 374

  Fly   578 ALFFGICIACFSALRSLIAVELIGLEKLTNAYGFLMLFQGLAATFGSPIAGGLYVMTGSYNAAFY 642
            .|.:|:.::...:|...:.::.:.:.:..:|.|.|.:.:.:....|.|:||.|...|..|...|.
Zfish   375 VLTYGLSMSVVGSLMFTVLMDTVEMSRFPSALGLLSIMESVTLLIGPPLAGFLVDRTQLYTYVFM 439

  Fly   643 FAGGLILLSA-FLCYPLTWV-SRWEERRNEKLTP 674
            ....:::||| ||.:...|: ||...:::....|
Zfish   440 ACTIIVVLSALFLMFTFYWLDSRDAAKKDSPAKP 473

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8468	NP_610940.1	MFS_MCT_SLC16	49..>225	CDD:340910	48/176 (27%)
		MFS	<477..658	CDD:475125	47/183 (26%)
slc16a5a	XP_021336012.1	MFS_MCT6	49..456	CDD:340983	118/612 (19%)