Protein Alignment CG8468 and slc16a12b

DIOPT Version :10

• Sequence 1: NP_610940.1
• Gene: CG8468 / 36577
• FlyBaseID: FBgn0033913
• Length: 678
• Species: Drosophila melanogaster
• Sequence 2: NP_001139286.1
• Gene: slc16a12b / 449947
• ZFINID: ZDB-GENE-050522-80
• Length: 488
• Species: Danio rerio
• Alignment Length: 643
• Identity: 140/643 - (21%)
• Similarity: 232/643 - (36%)
• Gaps: 210/643 - (32%)

  Fly    41 VVPPDSGWAWVVMVASFLCCTVIDGIVFCSGLIQEQLMAEFGVSKAYVAFVSSLLSGCYLMAGPF 105
            |:|||.||.|:::...|:.......:..|..:...:....|....:..|::.||:....::..|.
Zfish    21 VLPPDGGWGWMIVAGCFVVTVCTRAVTRCISIFFVEFQMHFAKDYSGTAWIHSLVDCTTMLCAPL 85

  Fly   106 VSAMANRFGFRPVTITGAIFAAICFGLSYFATSVEYLFLIYGVLGGIGFCMVYIPAVVIIGFYFE 170
            .|.:.|:...|...|.|...|::...||.||||:|||:...|:|.|:||.:.|.||:.::|.||.
Zfish    86 GSLIGNQLSCRIAVILGGFLASVGLVLSSFATSLEYLYATLGLLTGLGFALCYTPAIAMVGIYFC 150

  Fly   171 KWRALATGVAMCGSGVGTFVFAPLTKILLKS-GWRYTLAIQGIIVLSCALFGLAFRPIQPITLSV 234
            :.:|||.|:||.|||:|||:.||:.::|::. .||..|.|.|..||:..:.|...|||      :
Zfish   151 ERKALAYGIAMSGSGIGTFILAPVVQLLIEHYSWRGALLILGGFVLNLCVCGALLRPI------I 209

  Fly   235 TNEEGDEQEKKKLNGHGNTVAPTPQLHQAAFTKPLP-EGRFAYSMPNSAHNTYMGASQRNHYPTA 298
            ..||                       :|.   ||| :....||:
Zfish   210 LKEE-----------------------EAC---PLPVDSECGYSV-------------------- 228

  Fly   299 QEIFKGMNLERRPSGTAQGSKGTELKQLRKSQPTTPNGDPQQLTFNLHKELTTVGENEEEAENDN 363
                                           :|.|.||.|
Zfish   229 -------------------------------KPPTLNGGP------------------------- 237

  Fly   364 LLETEAKPVTIQARRHTVSGRRPQDIGKRSAAAAHEAHHGQSHSSSRPMYRDDIFFSGSLTRIPQ 428
                                       .||||:
Zfish   238 ---------------------------TRSAAS-------------------------------- 243

  Fly   429 YQSQTSLAYHMSVTRLPTKQDMLEDRQKGCRICPEAVRRTLSTMLDTTLLKSPAFMCLAFSGFLT 493
                                              :|.:|...:|.:...|..|.|:.||.|..|.
Zfish   244 ----------------------------------DAKQRCFQSMQEYHFLLMPDFLVLAGSFLLL 274

  Fly   494 MMGFFVPFTFLVDRAKAAGMDEQAAYGVLSGIGVVNTFARIVCGSLSSFPAVKPLWLNNFALTAG 558
            ..|..:||.:||..|...|:..|.|..::|.:||::....|..|.|:....:|. :.|...:.|.
Zfish   275 ASGCSLPFVYLVPYALDVGVGHQHAAFLMSILGVIDIVGNITFGWLTDRRCLKK-YRNICYMFAV 338

  Fly   559 GIATICSGIVINTAT-QW--TFALFFGICIACFSALRSLIAVELIGLEKLTNAYGFLMLFQGLAA 620
            |:..:|...:....| .|  .|::.:|.....:.||..::..:::|.:.|::|.|.:.....:..
Zfish   339 GMEGLCCLFIPLLRTFVWLVPFSVLYGYFDGAYVALIPVVTSDVVGRQYLSSALGVVYFLHAVPY 403

  Fly   621 TFGSPIAGGLYVMTGSYNAAFYFAGGLILLSAFLCYPLTWVSRWEERRNEK--LTPLP 676
            ....||.|.|...||:|.|.|:.:|..::.|:.|.:.:. :.|:.:|..:|  |:.:|
Zfish   404 LVSPPIGGWLVDTTGTYTATFFLSGFALISSSLLLFSVA-IIRYCQRNQKKNSLSKIP 460

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8468	NP_610940.1	MFS_MCT_SLC16	49..>225	CDD:340910	57/176 (32%)
		MFS	<477..658	CDD:475125	49/183 (27%)
slc16a12b	NP_001139286.1	MFS_MCT12	29..430	CDD:340982	127/602 (21%)