Protein Alignment CG8468 and hrm

DIOPT Version :10

• Sequence 1: NP_610940.1
• Gene: CG8468 / 36577
• FlyBaseID: FBgn0033913
• Length: 678
• Species: Drosophila melanogaster
• Sequence 2: NP_610174.1
• Gene: hrm / 35499
• FlyBaseID: FBgn0033028
• Length: 658
• Species: Drosophila melanogaster
• Alignment Length: 685
• Identity: 163/685 - (23%)
• Similarity: 283/685 - (41%)
• Gaps: 112/685 - (16%)

  Fly    24 NIKEENEGEEEIEEAAVVVPPDSGWAWVVMVASFLCCTVIDGIVFCSGLIQEQLMAEFGVSKAYV 88
            |.|::.|.:        :||||.||.|:|::.|.|...:|.|.:...|::..:....|..|....
  Fly    38 NKKDDKEYD--------LVPPDGGWGWLVLLGSCLTNILIPGTIKSFGVLFSEFTDAFNSSPTKA 94

  Fly    89 AFVSSLLSGCYLMAGPFVSAMANRFGFRPVTITGAIFAAICFGLSYFATSVEYLFLIYGVLGGIG 153
            |::.:|....|...||..|.::.::.:|.||:.|...|::...||::|:|:|:|::.||||.|||
  Fly    95 AWIPALCYFLYSSLGPVSSILSVKYSYRTVTLLGGASASLGMILSFWASSIEFLYISYGVLVGIG 159

  Fly   154 FCMVYIPAVVIIGFYFEKWRALATGVAMCGSGVGTFVFAPLTKILLKS-GWRYTLAIQGIIVLSC 217
            ..:.:.|.|.|:..||.|.|.||.|:.:.||.:|:.:..||.:.||:: |:..:..|.|.|.|:.
  Fly   160 AGLSFPPTVYIVTSYFAKLRGLANGLCISGSALGSIILPPLLRWLLETYGYHGSCLIMGGITLNV 224

  Fly   218 ALFGLAFRPIQPITLSVTN---------EEGDEQEKKKLNGHGNTVAPTPQLHQAAFTKPLPEGR 273
            .:..|.:.|::...:.|..         ||.|.....|..   |...|.|:...|  .|||
  Fly   225 FVAALFYEPVEQHMVRVPRARQALENIPEEEDIGIVMKFE---NVDEPVPKNEPA--DKPL---- 280

  Fly   274 FAYSMPNSAHNTYMGASQRNHYPTAQEIFKGMNLERRPSGTAQG-SKGTELKQLRKSQPTTPNGD 337
            ..|:.|.|.  .|:...:|..:           :....:...|. ||..:..|.|..:.:||...
  Fly   281 LPYNSPPSP--LYLPGDERLQF-----------VRSASAAVVQSYSKSGDEFQSRSRKISTPVRL 332

  Fly   338 PQQ-LTF-----NLHKELTTVGENEEEAENDNLLETEAKPVTIQARRHTVSGRRPQDIGKRSAAA 396
            ||: .||     |....|..|.|....:....|             |::...|    :.|||.
  Fly   333 PQRNQTFTPGQLNSQSSLYAVPEGRSSSNKLTL-------------RNSSKSR----LSKRSP-- 378

  Fly   397 AHEAHHGQSHSSSRPMYRDDIFFSGSLTRIPQYQSQTSLAYHMSVTRL----------PTKQD-- 449
                      |:|..:|....:...:|:..|:     ..:.|:|:..:          .|.||
  Fly   379 ----------STSSFLYVSTPYHGSTLSFQPK-----EFSSHLSLRSMGSSGTGHAGDSTGQDGS 428

  Fly   450 MLEDRQKGCRICPEAVRRTLSTMLDTTLLKSPAFMCLAFSGFLTMMGFFVPFTFLVDRAKAAGMD 514
            ..:...:|     :|.:...|...|.:|||.|.::.:..|.....:.:......|....:|.|.:
  Fly   429 YADVDARG-----QAQQPQRSKFFDLSLLKDPMYLVILISNSTNAISYTNFIILLPSFGEARGFN 488

  Fly   515 EQAAYGVLSGIGVVNTFARIVCGSLSSFPAVKPLWLNNFALTAGGIATICSGIVINTAT-QWTFA 578
            :..:..:||.:...:...||...:||....:...|     ...||::  .||:.:.... .||::
  Fly   489 KSLSAYLLSVVSATDLIGRIGGSALSDMGYIPKTW-----YFVGGLS--ISGLSLALLPFAWTYS 546

  Fly   579 ------LFFGICIACFSALRSLIAVELIGLEKLTNAYGFLMLFQGLAATFGSPIAGGLYVMTGSY 637
                  ..||:....:..:.::|..:::|.|:||::||..:...||....|.|:....:.....|
  Fly   547 SVCFWCALFGLASGIYVGITAVIMADMLGTERLTSSYGISLFVNGLLQLVGPPLCNYWFEAVNDY 611

  Fly   638 NAAFYFAGGLILLSAFLCYPLTWVSRWEERRNEKL 672
            |..|:..|..:|..|.|...:.|::|.:....|:|
  Fly   612 NPLFHALGLTLLAGASLWSFMPWINRRKANAEEQL 646

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8468	NP_610940.1	MFS_MCT_SLC16	49..>225	CDD:340910	56/176 (32%)
		MFS	<477..658	CDD:475125	41/187 (22%)
hrm	NP_610174.1	MFS_MCT_SLC16	55..>231	CDD:340910	56/175 (32%)
		MFS	<451..633	CDD:475125	41/188 (22%)