Protein Alignment CG8468 and Slc16a14

DIOPT Version :10

• Sequence 1: NP_610940.1
• Gene: CG8468 / 36577
• FlyBaseID: FBgn0033913
• Length: 678
• Species: Drosophila melanogaster
• Sequence 2: NP_001101699.2
• Gene: Slc16a14 / 316578
• RGDID: 1309675
• Length: 512
• Species: Rattus norvegicus
• Alignment Length: 662
• Identity: 157/662 - (23%)
• Similarity: 255/662 - (38%)
• Gaps: 193/662 - (29%)

  Fly    23 ENIKEENEGEEEIEEAAVVVPP---DSGWAWVVMVASFLCCTVIDGIVFCSGLIQEQLMAEFGVS 84
            |:|..:.|.:.:.:....:.|.   |.||||:::::||....:|.|.....|::..:.:.||..|
  Rat     6 EDIGYDLEDDRKAKNKKTLKPHPDIDGGWAWMMVLSSFFVHILIMGSQMALGVLNVEWLEEFHQS 70

  Fly    85 KAYVAFVSSLLSGCYLMAGPFVSAMANRFGFRPVTITGAIFAAICFGLSYFATSVEYLFLIYGVL 149
            :...|:||||..|..|:.|||:....|..|.|...|.|.:..::.:.||.:|.:|:.||:.:||.
  Rat    71 RGLTAWVSSLSMGITLIVGPFIGLFINTCGCRQTAIIGGLVNSLGWVLSAYAANVQSLFITFGVA 135

  Fly   150 GGIGFCMVYIPAVVIIGFYFEKWRALATGVAMCGSGVGTFVFAPLTKIL-LKSGWRYTLAIQGII 213
            .|:|..|.|:||||::|.||:|.||||.|::..|:|.|||:...|.|.| .:.|||..:.|||.:
  Rat   136 AGLGSGMAYLPAVVMVGRYFQKRRALAQGLSTTGTGFGTFLMTVLLKYLCAEYGWRNAMFIQGAL 200

  Fly   214 VLSCALFGLAFRPIQPITLSVTNEEGDEQEKKKLNGHGNTVAPTPQLHQAAFTKPLPEGRFAYSM 278
            .|:..:.|...||:.|  ..|.|..|.|:                           |....|||
  Rat   201 SLNLCVCGALMRPLSP--EKVENCSGAEE---------------------------PCALPAYS- 235

  Fly   279 PNSAHNTYMGASQRNHYPTAQEIFKGMNLERRPSGTAQGSKGTELKQLRKSQPTTPNGDPQQLTF 343
                                                      ||         :..:|.|..:|
  Rat   236 ------------------------------------------TE---------SVKSGGPLDMT- 248

  Fly   344 NLHKELTTVGENEEEAENDNLLETEAKPVTIQARRHTVSGRRPQDIGKRSAAAAHEAHHGQSHSS 408
                        ||:         :.:|    ....||...:.|::            .||:|
  Rat   249 ------------EEQ---------DRRP----GNEETVCDLQTQEL------------QGQTH-- 274

  Fly   409 SRPMYRDDIFFSGSLTRIPQYQSQTSLAYHMSVTRLPTKQDMLEDRQKGCRICPEAVRRTLSTML 473
                              |:   :...|:.:    |.|...:....|:|.|........|.|
  Rat   275 ------------------PR---KNVCAFRV----LKTVGQLTVRVQRGFRDWHSGYFGTAS--- 311

  Fly   474 DTTLLKSPAFMCLAFSGFLTMMGFFVPFTFLVDRAKAAGMDEQ-AAYGVLSGIGVVNTFARIVCG 537
               |..:..|:...|........|.:||..|.:......:.|| .|:.:.|.|.:::.|.:::.|
  Rat   312 ---LFTNRMFVAFIFWALFAYSSFVIPFIHLPEIVSLYNLSEQNDAFPLTSIIAILHIFGKVILG 373

  Fly   538 SLSSFPAVKPLW----LNNFAL-----------TAGGIATICSGIVINTATQWTFALFFGICIAC 587
            :::..|.:. :|    :.||.|           |...:|.||:              ..|.....
  Rat   374 AVADLPCIS-VWNVFLIANFTLVLSIFLLPLMHTYASLAVICA--------------LIGFSSGY 423

  Fly   588 FSALRSLIAVELIGLEKLTNAYGFLMLFQGLAATFGSPIAGGLYVMTGSYNAAFYFAG-----GL 647
            || |..::..:|:|.|.|.||||.::...|::|..|.|.||.::.:|..|:.:||..|     |:
  Rat   424 FS-LMPVVTEDLVGTEHLANAYGIIICANGISALLGPPFAGWIFDITQKYDFSFYICGLLYMVGI 487

  Fly   648 ILLSAFLCYPLT 659
            :.|....|..:|
  Rat   488 LFLLIQPCIQMT 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8468	NP_610940.1	MFS_MCT_SLC16	49..>225	CDD:340910	66/176 (38%)
		MFS	<477..658	CDD:475125	49/201 (24%)
Slc16a14	NP_001101699.2	MFS_MCT14	35..494	CDD:340987	148/626 (24%)