Protein Alignment CG8468 and Slc16a11

DIOPT Version :10

• Sequence 1: NP_610940.1
• Gene: CG8468 / 36577
• FlyBaseID: FBgn0033913
• Length: 678
• Species: Drosophila melanogaster
• Sequence 2: XP_038941393.1
• Gene: Slc16a11 / 287450
• RGDID: 1311125
• Length: 593
• Species: Rattus norvegicus
• Alignment Length: 694
• Identity: 145/694 - (20%)
• Similarity: 222/694 - (31%)
• Gaps: 259/694 - (37%)

  Fly     9 QDELASKG--LVSKQPENIKEENEGEEEIEEAAVVV----PPDSGWAWVVMVASFLCCTVIDGIV 67
            |.|..|:|  |.|:.| .::....|....::.|:..    |||.||.|||..|:|....:..|::
  Rat   115 QPEAGSQGRQLPSRGP-GVETSFTGVSPPQQTAMTPKPAGPPDGGWGWVVAAAAFAVNGLSYGLL 178

  Fly    68 FCSGLIQEQLMAEFGVSKAYVAFVSSLLSGCYLMAGPFVSAMANRFGFRPVTITGAIFAAICFGL 132
            ...||....|...|..|....|:||:|.......|.|..||::.|:|.|||.:.|.:..::....
  Rat   179 RSLGLALPDLAEHFERSAQDTAWVSALALAVQQAASPVGSALSTRWGARPVVMVGGVLTSLGLVF 243

  Fly   133 SYFATSVEYLFLIYGVLGGIGFCMVYIPAVVIIGFYFEKWRALATGVAMCGSGVGTFVFAPLTKI 197
            |.||.|:.:|:|..|:|.|.|:.:|:.||:..:..||.:.|.||.|:|:.|:|..:.:.||..:.
  Rat   244 SAFARSLLHLYLGLGLLAGSGWALVFAPALGTLSRYFSRRRVLAVGLALTGNGASSLLLAPALQF 308

  Fly   198 LLKS-GWRYTLAIQGIIVLSCALFGLAFRPIQPITLSVTNEEGDEQEKKKLNGHGNTVAPTPQLH 261
            ||.: |||..|.:.|.:.|.....|...|   |:.||                 |:.:||
  Rat   309 LLDTFGWRGALLLLGAVTLHLTPCGALLR---PLALS-----------------GDPLAP----- 348

  Fly   262 QAAFTKPLPEGRFAYSMPNSAHNTYMGASQRNHYPTAQEIFKGMNLERRPSGTAQGSKGTELKQL 326
                                                                             
  Rat   349 ----------------------------------------------------------------- 348

  Fly   327 RKSQPTTPNGDPQQLTFNLHKELTTVGENEEEAENDNLLETEAKPVTIQARRHTVSGRRPQDIGK 391
                |.||              |..:|                                   :|
  Rat   349 ----PRTP--------------LAALG-----------------------------------LG- 359

  Fly   392 RSAAAAHEAHHGQSHSSSRPMYRDDIFFSGSLTRIPQYQSQTSLAYHMSVTRLPTKQDMLEDRQK 456
                                                                             
  Rat   360 ----------------------------------------------------------------- 359

  Fly   457 GCRICPEAVRRTLSTMLDTTLLKSPAFMCLAFSGFLTMMGFFVPFTFLVDRAKAAGMDEQAAYGV 521
                                |.:.|||...|....|...|:|||:..|...|...||....|..|
  Rat   360 --------------------LFRRPAFSVFALGTALIGGGYFVPYVHLGPHALDQGMGGYGAALV 404

  Fly   522 LSGIGVVNTFARIVCGSLSSFPAVK-PLWLNNF-ALTAGGIATICSGIV--INTATQWTFALF-- 580
            ::...|.:..||:|.|.|:....|. |..|..| :||  |:..:..|:|  :.|...|...|.
  Rat   405 VAVAAVGDASARLVSGWLADQGWVPLPRLLVVFGSLT--GLGVLAVGLVPTVGTEEGWGAPLLAA 467

  Fly   581 ---FGICIACFSALRSLIAVELIGLEKLTNAYGFLMLFQGLAATFGSPIAGGLYVMTGSYNAAFY 642
               :|:....::.|...:...|:|:..:..|.|.:|:...|....|.|::|.|...||.::|:|.
  Rat   468 AGAYGLSAGSYAPLVFGVLPGLVGIGGVVQATGLVMMLMSLGGLLGPPLSGFLRDKTGDFSASFL 532

  Fly   643 FAGGLILLSAFL----------CYPLTWVSRWEERRNEKLTPLP 676
            .....||..:|:          |.|.:..:.....|.| |.|:|
  Rat   533 VCSSFILSGSFIYMGLPRALPSCRPASPPATPPPERGE-LLPVP 575

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8468	NP_610940.1	MFS_MCT_SLC16	49..>225	CDD:340910	58/176 (33%)
		MFS	<477..658	CDD:475125	54/199 (27%)
Slc16a11	XP_038941393.1	PHA03378	<42..158	CDD:223065	12/43 (28%)
		MFS_MCT11_13	160..549	CDD:340981	124/619 (20%)