Protein Alignment CG8468 and Slc16a4

DIOPT Version :10

• Sequence 1: NP_610940.1
• Gene: CG8468 / 36577
• FlyBaseID: FBgn0033913
• Length: 678
• Species: Drosophila melanogaster
• Sequence 2: NP_666248.1
• Gene: Slc16a4 / 229699
• MGIID: 2385183
• Length: 500
• Species: Mus musculus
• Alignment Length: 632
• Identity: 137/632 - (21%)
• Similarity: 241/632 - (38%)
• Gaps: 152/632 - (24%)

  Fly    43 PPDSGWAWVVMVASFLCCTVIDGIVFCSGLIQEQLMAEFGVSKAYVAFVSSLLSGCYLMAGPFVS 107
            |.|.||.|:|::..||....:.|:.....:.......||..:...:.::.|::|.....|||..:
Mouse    14 PLDGGWGWMVVLHFFLVNVFVMGMTKTFAIFFVVFQEEFEGTSEQIGWIGSIMSSLRFSAGPLAA 78

  Fly   108 AMANRFGFRPVTITGAIFAAICFGLSYFATSVEYLFLIYGVLGGIGFCMVYIPAVVIIGFYFEKW 172
            .:.:..|.:..:|.|....:..:.:|.:||.:.:|.:..|:|.|:|...:|..|.|:|..||:|.
Mouse    79 IICDVLGEKATSILGTFLVSGGYVISSWATGIPFLCVTMGLLPGLGSAFLYQVAAVVITKYFKKR 143

  Fly   173 RALATGVAMCGSGVGTFVFAPLTKILLK-SGWRYTLAIQGIIVLSCALFGLAFRPIQPITLSVTN 236
            ..|:|.:|..|.|: ||:.||.||.|:. ..|...|.:.|.|:|:.....:..|||.    |.:|
Mouse   144 LGLSTAIARSGMGL-TFLLAPFTKFLIDLYDWTGALILFGAIILNLVPSSMLLRPIH----SQSN 203

  Fly   237 EEGDEQEKKKLNGHGNTVAPTPQLHQAAFTKPLPEGRFAYSMPNSAHNTYMGASQRNHYPTAQEI 301
            ...|.:.|      |:.::.|.                    |.:::.|.....:....|..::
Mouse   204 NNSDIENK------GSILSATE--------------------PEASYKTETSKCKETQEPFIKD- 241

  Fly   302 FKGMNLERRPSGTAQGSKGTELKQLRKS-QPTTPNGDPQQLTFNLHKELTTVGENEEEAENDNLL 365
                                  ..::|| ||||              .||.:|...||..|
Mouse   242 ----------------------STMKKSEQPTT--------------TLTVLGNQSEEFSN---- 266

  Fly   366 ETEAKPVTIQARRHTVSGRRPQDIGKRSAAAAHEAHHGQSHSSSRPMYRDDIFFSGSLTRIPQYQ 430
                       |.|.   .||..:.           :|:||...        |.|.:.
Mouse   267 -----------RPHR---NRPLLMS-----------NGKSHKKK--------FVSWNC------- 291

  Fly   431 SQTSLAYHMSVTRLPTKQDMLEDRQKGCRICPEAVRRTLSTMLDTTLLKSPAFMCLAFSGFLTMM 495
                                   :||               :||.:|.::|.|....:|..|:.:
Mouse   292 -----------------------KQK---------------LLDISLFRNPFFYIFTWSFLLSQL 318

  Fly   496 GFFVPFTFLVDRAKAAGMDEQAAYGVLSGIGVVNTFARIVCGSLSSFPAVKPLWLNNFALTAGGI 560
            .:|:|...||.|||..|:|...|..::|..|:..|.::::.|.::....:|....:...|...|:
Mouse   319 AYFIPTFHLVARAKTLGIDVMDASYLVSVAGITETVSQLISGWIADQNWIKKYQYHKSYLILCGV 383

  Fly   561 ATICSGIVINTATQWTFALFFGICIACFSALRSLIAVELIGLEKLTNAYGFLMLFQGLAATFGSP 625
            ..:.:.:.........:.:.|.|....:.||...:.|:|....::....|:...|.|:|...|.|
Mouse   384 TNLLAPLATTFPLLMAYTILFAIFAGGYLALILPVLVDLSKNSRVHKFLGYASFFAGIAVLSGPP 448

  Fly   626 IAGGLYVMTGSYNAAFYFAGGLILLSAFLCYPLTWVSRWEERRNEKL 672
            |||.:|..|.:|..:|||:|...:||:...:.:....||:.::::.|
Mouse   449 IAGWIYDYTQTYTGSFYFSGTCYILSSVSLFFVPLAERWKRKQSDLL 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8468	NP_610940.1	MFS_MCT_SLC16	49..>225	CDD:340910	47/176 (27%)
		MFS	<477..658	CDD:475125	46/180 (26%)
Slc16a4	NP_666248.1	MFS_MCT5	20..486	CDD:340979	130/615 (21%)