Protein Alignment CG8468 and mct-3

DIOPT Version :10

• Sequence 1: NP_610940.1
• Gene: CG8468 / 36577
• FlyBaseID: FBgn0033913
• Length: 678
• Species: Drosophila melanogaster
• Sequence 2: NP_510308.1
• Gene: mct-3 / 181497
• WormBaseID: WBGene00010834
• Length: 596
• Species: Caenorhabditis elegans
• Alignment Length: 692
• Identity: 216/692 - (31%)
• Similarity: 325/692 - (46%)
• Gaps: 163/692 - (23%)

  Fly    15 KGLVSKQPENIKEENEGEEEIEEAAVVVPPDSGWAWVVMVASFLCCTVIDGIVFCSG-LIQEQLM 78
            |....:.||.:      |:|:|:|..:.|||.|:.|.::.||||...::||::|..| ::|...:
 Worm    11 KAAAHQDPETV------EKELEDAGFIAPPDGGYGWAIVAASFLLNMIVDGVIFTVGKILQPAWV 69

  Fly    79 AEFGVSKAYVAFVSSLLSGCYLMAGPFVSAMANRFGFRPVTITGAIFAAICFGLSYFATSVEYLF 143
            ..||:|:|..|...|:|||||..|||..|.:.|.||.|.|.:.|::.||:.|.||..|.::..|:
 Worm    70 HSFGISEASAAMTMSILSGCYFFAGPIASVLCNVFGCRQVALAGSLIAALGFLLSISAPNIYVLY 134

  Fly   144 LIYGVLGGIGFCMVYIPAVVIIGFYFEKWRALATGVAMCGSGVGTFVFAPLTKIL---LKSGWRY 205
            :.:|::.|.||.|:|:||:|||..||.|.|::|||:|:||||:||.|||.|..::   :...|:.
 Worm   135 VSFGLIAGAGFGMMYLPAIVIISQYFAKKRSVATGIAVCGSGIGTTVFALLNDVVWDFVGGDWKQ 199

  Fly   206 TLAIQGIIVLS----CALFGLAFRPIQPITLSVTNEEGDEQEK-----KKLNGHGNTVAPTPQLH 261
            .|.....:.:|    |.|    .||::|        ..|:.||     :....|...|..:|.|
 Worm   200 FLVYTAAVTISGLGACIL----LRPLKP--------SKDQIEKVAKVLEDYEEHKEKVPESPLL- 251

  Fly   262 QAAFTKPLPEGRFAYSMPNSAHNTYMGASQRNHYPTAQEIFKGMNLERRPSGTAQGSKGTELKQL 326
                               |.|||...:|...|  ||.::..|.:
 Worm   252 -------------------SKHNTPFLSSLELH--TAGKLENGHH-------------------- 275

  Fly   327 RKSQPTTPNGDPQQLTFNLHKELTTVGENEEEAENDNLLETEAKPVTIQARRHTVSGRRPQDIGK 391
                    .|..:.:...:.||:                                     :|:.|
 Worm   276 --------TGSIKSIVDAVSKEI-------------------------------------EDLNK 295

  Fly   392 RSAAAAHEAHHGQSHSSSRPMYRDDIFFSGS------------LTRIPQYQSQTSLAYHMSV--- 441
                               |:.|.|||:|||            :||....:.|.||.:...|
 Worm   296 -------------------PLLRKDIFYSGSTTNIAARSRTGTMTREEAAEHQQSLRFRGKVETP 341

  Fly   442 TRLPTKQDMLEDRQKGCRICPEA----VRRTLSTMLDTTLLKSPAFMCLAFSGFLTMMGFFVPFT 502
            .:..:|.|:.........|..|:    :::.|..::|..||.||:|:.|||||.||:..|:|||.
 Worm   342 QQYLSKADLNAGDNGDVAIANESKIQEIKQALKQLVDKELLFSPSFLLLAFSGTLTLCCFYVPFI 406

  Fly   503 FLVDRA-KAAGMDEQAAYGVLSGIGVVNTFARIVCGSLSSFPAVKPLWLNNFALTAGGIATICSG 566
            :|.:.. |..|:........:|.|||:|..|||.||.|:..|.|..|.:|||||.|.|:||:.
 Worm   407 YLGNHLDKIEGLTTAEKSFTVSLIGVLNIVARIGCGILADRPEVSALAVNNFALIAAGLATMT-- 469

  Fly   567 IVINTATQWTFALF---FGICIACFSALRSLIAVELIGLEKLTNAYGFLMLFQGLAATFGSPIAG 628
            :.:.|| .|.|..|   |.|.:|||:||||:|.|||||||||:||:|.|:.|.|:.|..|||:|.
 Worm   470 VPLYTA-YWQFLAFCVPFSIGVACFAALRSIIVVELIGLEKLSNAFGILLTFMGVGAVVGSPLAA 533

  Fly   629 GLYVMTGSYNAAFYFAGGLILLSAFLCYPLTWVSRWEERRNE 670
            .:...||:::.:||..|.|:.:|..:|.||..:.:.|..|::
 Worm   534 AMKDYTGNFDTSFYVMGALMTISGAMCIPLGGLRKRELARSD 575

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8468	NP_610940.1	MFS_MCT_SLC16	49..>225	CDD:340910	72/183 (39%)
		MFS	<477..658	CDD:475125	85/184 (46%)
mct-3	NP_510308.1	MFS_MCT_SLC16	39..563	CDD:340910	201/644 (31%)