Protein Alignment CG8468 and Slc16a10

DIOPT Version :10

• Sequence 1: NP_610940.1
• Gene: CG8468 / 36577
• FlyBaseID: FBgn0033913
• Length: 678
• Species: Drosophila melanogaster
• Sequence 2: NP_620186.1
• Gene: Slc16a10 / 170566
• RGDID: 69197
• Length: 514
• Species: Rattus norvegicus
• Alignment Length: 678
• Identity: 146/678 - (21%)
• Similarity: 218/678 - (32%)
• Gaps: 252/678 - (37%)

  Fly    14 SKGLVSKQPENIKEENEGEEEIEEAAVVVPPDSGWAWVVMVASFLCCTVIDGIVFCSGLIQEQLM 78
            |.|.|.|....:......:|..|      ||:.||.|:||:|:..|...:.||....|::...::
  Rat    40 SDGSVEKVEVELTRSTGNQEPPE------PPEGGWGWLVMLAAMWCNGSVFGIQNAYGVLFVSML 98

  Fly    79 AEFGV----SKAY-VAFVSSLLSGCYLMAGPFVSAMANRFGFRPVTITGAIFAAICFGLSYFATS 138
            ..||.    :.|: .|:|.||..|......|.||...:.||.|...:.||....:....|.|.:|
  Rat    99 ETFGAKDDDNMAFKAAWVGSLSMGMIFFCCPIVSVFTDMFGCRRTAVLGAAVGFVGLMSSSFVSS 163

  Fly   139 VEYLFLIYGVLGGIGFCMVYIPAVVIIGFYFEKWRALATGVAMCGSGVGTFVFAPLTKILLKS-- 201
            :|.|:..|||:...|....|.|::||:|.||:|...|..|:...||.|.| :..||....|.|
  Rat   164 IEPLYFTYGVVFACGCSFAYQPSLVILGHYFKKRLGLVNGIVTAGSSVFT-ILLPLLLGNLTSTV 227

  Fly   202 GWRYTLAIQGIIVLSCALFGLAFRPIQPITLSVTNEEGDEQEKKKLNGHGNTVAPTPQLHQAAFT 266
            |..|||.|..|.:....|.|..:||:.|
  Rat   228 GLCYTLRILCIFMFVLFLAGFTYRPLVP------------------------------------- 255

  Fly   267 KPLPEGRFAYSMPNSAHNTYMGASQRNHYPTAQEIFKGMNLERRPSGTAQGSKGTELKQLRKSQP 331
                                                                             
  Rat   256 ----------------------------------------------------------------- 255

  Fly   332 TTPNGDPQQLTFNLHKELTTVGENEEEAENDNLLETEAKPVTIQARRHTVSGRRPQDIGKRSAAA 396
                                 ...|:|:|:
  Rat   256 ---------------------SSKEKESED----------------------------------- 264

  Fly   397 AHEAHHGQSHSSSRPMYRDDIFFSGSLTRIPQYQSQTSLAYHMSVTRLPTKQDMLEDRQKGCRIC 461
                    |.||         |||
  Rat   265 --------SRSS---------FFS----------------------------------------- 271

  Fly   462 PEAVRRTLS---TMLDTTLLKSPAFMCLAFSGFLTMMGFFVPFTFLVDRAKAAGMDEQAAYGVLS 523
                ||.||   .:.:..|.|..|:...|....|.:.|:|||:..|::..|....|......:..
  Rat   272 ----RRKLSPPKKIFNFALFKETAYAVWAAGIPLALFGYFVPYVHLMNHVKERFKDVNNKEVLFM 332

  Fly   524 GIGVVNTFARIVCGSLSSF-PAVKPLWLNNFALTAGGIAT----ICS--GIVINTATQWTFALFF 581
            .|||.:...|::.|.::.: |.||.::|...:....|:.:    :||  |.:|      ...|..
  Rat   333 CIGVTSGVGRLLFGRIADYLPGVKKVYLQVLSFFFIGLTSMMIPLCSVFGALI------ALCLIM 391

  Fly   582 GICIACFSALRSLIAVELIGLEKLTNAYGFLMLFQGLAATFGSPIAGGLYVMTGSYNAAFYFAG- 645
            |:...||.::.:.||.||:|.:..:.|.|||:.|..:..|.|.|:||.|:...|||:.|||.||
  Rat   392 GLFDGCFISIMAPIAFELVGPQDASQAIGFLLGFMSIPMTVGPPVAGLLHDKLGSYDLAFYLAGI 456

  Fly   646 GLILLSAFLCYPLTWVSRWEERRNEKLT 673
            ...:..|.||. :.|:...::|...|.|
  Rat   457 PPFIGGAVLCL-IPWIHSKKQREISKNT 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8468	NP_610940.1	MFS_MCT_SLC16	49..>225	CDD:340910	59/182 (32%)
		MFS	<477..658	CDD:475125	57/188 (30%)
Slc16a10	NP_620186.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..64		6/29 (21%)
		MFS	69..469	CDD:475125	132/627 (21%)