Protein Alignment CG8468 and SLC16A11

DIOPT Version :10

• Sequence 1: NP_610940.1
• Gene: CG8468 / 36577
• FlyBaseID: FBgn0033913
• Length: 678
• Species: Drosophila melanogaster
• Sequence 2: NP_699188.2
• Gene: SLC16A11 / 162515
• HGNCID: 23093
• Length: 447
• Species: Homo sapiens
• Alignment Length: 620
• Identity: 129/620 - (20%)
• Similarity: 195/620 - (31%)
• Gaps: 237/620 - (38%)

  Fly    43 PPDSGWAWVVMVASFLCCTVIDGIVFCSGLIQEQLMAEFGVSKAYVAFVSSLLSGCYLMAGPFVS 107
            |||.||.|||..|:|....:..|::...||....|...|..|....|::|:|.......|.|..|
Human     8 PPDGGWGWVVAAAAFAINGLSYGLLRSLGLAFPDLAEHFDRSAQDTAWISALALAVQQAASPVGS 72

  Fly   108 AMANRFGFRPVTITGAIFAAICFGLSYFATSVEYLFLIYGVLGGIGFCMVYIPAVVIIGFYFEKW 172
            |::.|:|.|||.:.|.:.|::.|..|.||:.:.:|:|..|:|.|.|:.:|:.||:..:..||.:.
Human    73 ALSTRWGARPVVMVGGVLASLGFVFSAFASDLLHLYLGLGLLAGFGWALVFAPALGTLSRYFSRR 137

  Fly   173 RALATGVAMCGSGVGTFVFAPLTKILLKS-GWRYTLAIQGIIVLSCALFGLAFRPIQPITLSVTN 236
            |.||.|:|:.|:|..:.:.||..::||.: |||..|.:.|.|.|.....|....|:
Human   138 RVLAVGLALTGNGASSLLLAPALQLLLDTFGWRGALLLLGAITLHLTPCGALLLPL--------- 193

  Fly   237 EEGDEQEKKKLNGHGNTVAPTPQLHQAAFTKPLPEGRFAYSMPNSAHNTYMGASQRNHYPTAQEI 301
                             |.|
Human   194 -----------------VLP--------------------------------------------- 196

  Fly   302 FKGMNLERRPSGTAQGSKGTELKQLRKSQPTTPNGDPQQLTFNLHKELTTVGENEEEAENDNLLE 366
                                              |||
Human   197 ----------------------------------GDP---------------------------- 199

  Fly   367 TEAKPVTIQARRHTVSGRRPQDIGKRSAAAAHEAHHGQSHSSSRPMYRDDIFFSGSLTRIPQYQS 431
             .|.|                    ||..||
Human   200 -PAPP--------------------RSPLAA---------------------------------- 209

  Fly   432 QTSLAYHMSVTRLPTKQDMLEDRQKGCRICPEAVRRTLSTMLDTTLLKSPAFMCLAFSGFLTMMG 496
                                                     |..:|....||...|....|...|
Human   210 -----------------------------------------LGLSLFTRRAFSIFALGTALVGGG 233

  Fly   497 FFVPFTFLVDRAKAAGMDEQAAYGVLSGIGVVNTFARIVCGSLSSFPAVK-PLWLNNF-ALTAGG 559
            :|||:..|...|...|:....|..|::...:.:..||:|||.|:....|. |..|..| |||..|
Human   234 YFVPYVHLAPHALDRGLGGYGAALVVAVAAMGDAGARLVCGWLADQGWVPLPRLLAVFGALTGLG 298

  Fly   560 IATICSGIVINTATQW-----TFALFFGICIACFSALRSLIAVELIGLEKLTNAYGFLMLFQGLA 619
            :..:....|:.....|     ..|:.:|:....::.|...:...|:|:..:..|.|.:|:...|.
Human   299 LWVVGLVPVVGGEESWGGPLLAAAVAYGLSAGSYAPLVFGVLPGLVGVGGVVQATGLVMMLMSLG 363

  Fly   620 ATFGSPIAGGLYVMTGSYNAAFYFAGGLILLSAFL 654
            ...|.|::|.|...||.:.|:|..:|.|||..:|:
Human   364 GLLGPPLSGFLRDETGDFTASFLLSGSLILSGSFI 398

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8468	NP_610940.1	MFS_MCT_SLC16	49..>225	CDD:340910	59/176 (34%)
		MFS	<477..658	CDD:475125	52/185 (28%)
SLC16A11	NP_699188.2	MFS	14..403	CDD:475125	124/614 (20%)