Protein Alignment Uba3 and uba3

DIOPT Version :10

• Sequence 1: NP_610913.1
• Gene: Uba3 / 36539
• FlyBaseID: FBgn0263697
• Length: 450
• Species: Drosophila melanogaster
• Sequence 2: NP_998632.1
• Gene: uba3 / 406776
• ZFINID: ZDB-GENE-040426-2825
• Length: 462
• Species: Danio rerio
• Alignment Length: 431
• Identity: 276/431 - (64%)
• Similarity: 346/431 - (80%)
• Gaps: 6/431 - (1%)

  Fly    16 RFNGLRNILEREGPFCKDGFAASSENLEFLQTKCQVLIIGAGGLGCELLKDLALMGFGNLHVIDM 80
            |::.:|..|||.|||....|.||:|:|:||...|::|:||||||||||||||||.||.::||:||
Zfish    36 RWDHVRKFLERTGPFTHPDFEASTESLQFLLDTCKILVIGAGGLGCELLKDLALSGFRHIHVVDM 100

  Fly    81 DTIELSNLNRQFLFRRTDIGASKAECAARFINARVPTCRVTPHFKKIQDFDESFYQQFHLVVCGL 145
            |||::||||||||||..|:|..|||.||.|:|.|||.|.|.||||||||.||:||:|||:|||||
Zfish   101 DTIDVSNLNRQFLFRPKDVGRPKAEVAADFVNDRVPGCSVVPHFKKIQDLDETFYRQFHIVVCGL 165

  Fly   146 DSIVARRWINGMLLSMLRYEEDGTIDTSSIVPMIDGGTEGFKGNARVILPGFTACIECTLDLFPP 210
            ||::||||:||||||:|.| |||.:|.|||:|:||||||||||||||||||.||||:|||:|:||
Zfish   166 DSVIARRWMNGMLLSLLIY-EDGVLDPSSIIPLIDGGTEGFKGNARVILPGMTACIDCTLELYPP 229

  Fly   211 QVNYPLCTIANTPRLPEHCIEYVKIIQWEKQNPF--GVPLDGDDPQHIGWIYERALERSNEFNIT 273
            |:|:|:||||:.|||||||:|||:::.|.|:.||  ||.||||||:||.|:|:::|||:.|||||
Zfish   230 QINFPMCTIASMPRLPEHCVEYVRMLLWPKEKPFGDGVVLDGDDPKHIQWVYQKSLERAAEFNIT 294

  Fly   274 GVTYRLVQGVVKHIIPAVASTNAAIAAACALEVFKLATSCYDSMANYLNFNDLDGIYTYTYEAEK 338
            ||||||.|||||.||||||||||.||||||.||||:|||.|..:.|||.|||:||:||||:|||:
Zfish   295 GVTYRLTQGVVKRIIPAVASTNAVIAAACATEVFKIATSAYVPLNNYLVFNDVDGLYTYTFEAER 359

  Fly   339 SENCLACSNTPQPLPIEDPNTTTLEDVIKLLCDSPRFQLKSPALTTVMKDGKRRTLYMSGVKSIE 403
            .|||.|||..||.:....  :..|::|:..|.::...|:||||:||.: |||.:|||:..|.|||
Zfish   360 KENCSACSQVPQDMQFTP--SAKLQEVLDYLTENASLQMKSPAITTTL-DGKNKTLYLQTVASIE 421

  Fly   404 EATRKNLTQSLGELGLHDGQQLTVTDATSPSAMTLQLKYQS 444
            |.||.||:::|.||||.|||:|.|.|.|:|..:..:||:.|
Zfish   422 ERTRPNLSKTLKELGLVDGQELAVADVTTPQTVLFKLKFIS 462

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Uba3	NP_610913.1	Uba3_RUB	50..346	CDD:238765	215/297 (72%)
		E2_bind	357..442	CDD:462611	39/84 (46%)
uba3	NP_998632.1	Interaction with ube2m N-terminus. /evidence=ECO:0000250	52..69		7/16 (44%)
		Uba3_RUB	70..367	CDD:238765	215/297 (72%)
		Interaction with ube2m N-terminus. /evidence=ECO:0000250	156..160		2/3 (67%)
		Interaction with ube2m N-terminus. /evidence=ECO:0000250	191..216		21/24 (88%)
		Interaction with nedd8. /evidence=ECO:0000250	226..228		1/1 (100%)
		Interaction with nae1. /evidence=ECO:0000250	241..247		4/5 (80%)
		Interaction with nae1. /evidence=ECO:0000250	291..294		2/2 (100%)
		Interaction with ube2m N-terminus. /evidence=ECO:0000250	330..337		4/6 (67%)
		Interaction with nedd8. /evidence=ECO:0000250	351..356		4/4 (100%)
		Interaction with ube2m core domain. /evidence=ECO:0000250	367..462		43/97 (44%)
		E2_bind	377..460	CDD:462611	39/85 (46%)