Protein Alignment Uba3 and APP-BP1

DIOPT Version :10

• Sequence 1: NP_610913.1
• Gene: Uba3 / 36539
• FlyBaseID: FBgn0263697
• Length: 450
• Species: Drosophila melanogaster
• Sequence 2: NP_648435.1
• Gene: APP-BP1 / 39244
• FlyBaseID: FBgn0261112
• Length: 524
• Species: Drosophila melanogaster
• Alignment Length: 521
• Identity: 92/521 - (17%)
• Similarity: 154/521 - (29%)
• Gaps: 199/521 - (38%)

  Fly     1 MSVHSP-NPGLILQSKRFNGLRNILEREGPFCKDGFAASSENLEFLQTKCQVLIIGAGGLGCELL 64
            ||..:| :|.|..:||:::....:....|              :.|.....|.::....:|||..
  Fly     1 MSSPAPKSPELSDKSKKYDRQIRLWGEHG--------------QTLLEAATVCLVNVTAVGCETA 51

  Fly    65 KDLALMGFGNLHVIDMDTIELSNLNRQFLFRRTDIGASKAECAARFINARVPTCRVTPHFKKIQD 129
            |.|.|.|.|...|.|..|::..:|...|....:.:|.|||....:.:....|...        .|
  Fly    52 KGLVLPGIGGFTVADGSTVKEEDLGNNFFLDSSYLGKSKALACMQLLQELNPDVN--------GD 108

  Fly   130 F-DES----------FYQQFHLVVCG------LDSIVARRW-INGMLLSMLRYEEDGTIDTSSIV 176
            : |||          |:..|.||:..      |..:..|.| :|                    |
  Fly   109 YVDESADFLLANRPNFFDSFDLVIASNLNEQTLLLLAERLWELN--------------------V 153

  Fly   177 PMIDGGTEGFKGNARVILPGFTACIECTLDLFPP------QVNYPLCTIAN-------TPRLPEH 228
            |:|...:.|..|..|:.:..     .|.::..|.      ::.:|...:..       |.::|..
  Fly   154 PLIYCRSLGMLGTIRLQIRE-----HCIVEAHPDNRQFDLRLEHPFDALREHLDGTEVTSKVPWL 213

  Fly   229 CIEYVKIIQWEKQNPFG-------------------------------------------VP--- 247
            .:.:..:..|:||...|                                           ||
  Fly   214 LVLHKYLNVWQKQQADGTQTPRNYKEKNQLKETIREEMKADEENYEEAIKAVNTAFGAGQVPKSL 278

  Fly   248 --LDGDD-------PQHIGWIYERAL------ERSNEFNITGV---------------------- 275
              :..||       ..::.||..:||      |......:.||
  Fly   279 KAIFEDDACEQLNKKSNVFWIMAKALKHFVIHENEGHLPLPGVLPDMTANTDSYIALQHIYRQQA 343

  Fly   276 ------TYRLVQGVVKHI-IPAVASTNAAIAAAC----ALEVF---KLATSCYDSMANYLNF--- 323
                  .|...|..:|.: :||.:....::...|    .|.|.   ::|.. |:..:..|..
  Fly   344 LQDADQVYHKCQEYLKQLALPADSIDERSVRLICKEAAGLAVIRGTRIAEE-YEKSSRLLPLVED 407

  Fly   324 NDLDGIYT-YTYEAEKSENCLA-CSNTPQPLPIEDP-----------------NTTTLEDVIKLL 369
            |:|.|..| |.:.....|..|: |.|.|....:|..                 :.|..:||:..:
  Fly   408 NELQGNLTAYNFALRAYERFLSECGNIPGECIVEQDIGRLKSIAAKMLSDLGMHATISDDVLHEI 472

  Fly   370 C 370
            |
  Fly   473 C 473

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Uba3	NP_610913.1	Uba3_RUB	50..346	CDD:238765	75/428 (18%)
		E2_bind	357..442	CDD:462611	4/31 (13%)
APP-BP1	NP_648435.1	APPBP1_RUB	16..522	CDD:238770	86/506 (17%)