Protein Alignment Uba3 and Uba6

DIOPT Version :10

• Sequence 1: NP_610913.1
• Gene: Uba3 / 36539
• FlyBaseID: FBgn0263697
• Length: 450
• Species: Drosophila melanogaster
• Sequence 2: NP_766300.1
• Gene: Uba6 / 231380
• MGIID: 1913894
• Length: 1053
• Species: Mus musculus
• Alignment Length: 488
• Identity: 108/488 - (22%)
• Similarity: 186/488 - (38%)
• Gaps: 125/488 - (25%)

  Fly    20 LRNILEREGPFCKDGFAASSENLEFL-----------------------QTKCQ------VLIIG 55
            |:.:..:..|.|:..:..:::.:|.|                       .|.||      :.::|
Mouse   403 LKAVTGKFSPLCQWLYLEAADTVESLGNPGHEEFLPRGDRYDAIRACIGNTLCQKLQNLNIFLVG 467

  Fly    56 AGGLGCELLKDLALMGFGN------LHVIDMDTIELSNLNRQFLFRRTDIGASKAECAARFINAR 114
            .|.:|||:||:.||:|.|.      :.|.|.|.||.||||||||||...|...|:..||......
Mouse   468 CGAIGCEMLKNFALLGVGTGREKGMVTVTDPDLIEKSNLNRQFLFRPHHIQKPKSYTAAEATLKI 532

  Fly   115 VPTCRVTPHFKKI-----QDFDESFYQQFHLVVCGLDSIVARRWINGMLLSMLRYEEDGTIDTSS 174
            .|..::..|..|:     ..:.:.||.:..:::..||::.|||:::...|:.||
Mouse   533 NPQLKIDAHLNKVCPATESIYSDEFYTKQDIIITALDNVEARRYVDSRCLANLR----------- 586

  Fly   175 IVPMIDGGTEGFKGNARVILPGFTACIECTLDLFPPQVNYPLCTIANTPRLPEHCIEYVKIIQWE 239
              |::|.||.|.||:..:|:|..|.......|  ||:...|.||:.:.|...||      .|||.
Mouse   587 --PLLDSGTMGTKGHTEIIVPQLTESYNSHRD--PPEEEIPFCTLKSFPAAIEH------TIQWA 641

  Fly   240 KQNPFGVPLDGDDPQHIGWIYERAL-ERSNEFNITGVTYRLVQGVVKHIIPAVASTNAAIAAACA 303
            :..                 :|.:. .:.:.||.....|...:.|::.|      .|......|
Mouse   642 RDK-----------------FESSFSHKPSLFNKFWQAYPSAEDVLQKI------QNGQSLEGC- 682

  Fly   304 LEVFKLA-------TSCYD----SMANYLNFNDLDGIYTYTYEAEKSENCLACSNTPQPLPIEDP 357
            .:|.||.       :.|.:    ....|.|...|..::.:..|....:..|...:..:|
Mouse   683 FQVIKLLSRRPRIWSQCVELARLKFEKYFNHKALQLLHCFPLETRLKDGSLFWQSPKRP------ 741

  Fly   358 NTTTLEDVIKLLCDSP-RFQLKSPALTTVMKDGKR--RTLYMSGVKSIEEATRKNLTQSLGELGL 419
                         .|| :|.|..|...:.::...:  .|:|.... |.::.:..:|...|.|:.:
Mouse   742 -------------PSPIKFDLNEPLHLSFLQSAAKLYATVYCIPF-SEKDLSVNSLMDILSEVKI 792

  Fly   420 HD---GQQLTVTDATS--PSAMTLQLKYQSNEV 447
            .:   ..::..||.|:  |..:.:..:.:.|.|
Mouse   793 EEFKPSNKVVQTDETARKPDHVPVSSEDERNAV 825

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Uba3	NP_610913.1	Uba3_RUB	50..346	CDD:238765	83/324 (26%)
		E2_bind	357..442	CDD:462611	15/92 (16%)
Uba6	NP_766300.1	Ube1	38..1046	CDD:273603	108/488 (22%)