Protein Alignment tum and Arhgap45

DIOPT Version :9

• Sequence 1: NP_610912.2
• Gene: tum / 36538
• FlyBaseID: FBgn0086356
• Length: 625
• Species: Drosophila melanogaster
• Sequence 2: NP_001334003.1
• Gene: Arhgap45 / 70719
• MGIID: 1917969
• Length: 1127
• Species: Mus musculus
• Alignment Length: 625
• Identity: 136/625 - (21%)
• Similarity: 226/625 - (36%)
• Gaps: 154/625 - (24%)

  Fly    32 LRMFEQ-YHEKCAGY---AAETARIQNELDKSLTKMGDLEGKLFHARRIIDMEIKARRQAEHERD 92
            ||..:| |.::|..:   ..:.|:.:.|...:....|....|....||.::.|  |:.:||   :
Mouse   412 LRKAKQGYKQRCEDHDKARLQVAKAEEEQQGTGPGAGTAASKALDKRRRLEEE--AKNKAE---E 471

  Fly    93 AMESKIMAVADLLRHERNLNNETRDKLAFLHTLPSSRKRKSLNAVREDKSYGDINSTGSLLSDLS 157
            ||.:....|||....::.|.:               .|..:|..::|.....|.....:.:|...
Mouse   472 AMATYRTCVADAKTQKQELED---------------TKVTALRQIQEVIRQSDQTIKSATISYYQ 521

  Fly   158 ITHSEDDFLDV------RTSK------SWREHRPSLPKNQIPSV---------GNKRSRLSTGLN 201
            :.|.:...|.|      .:||      .:..|...|.:.:.|.|         .|..|.:.....
Mouse   522 LMHMQTAPLPVNFQMLCESSKLYDPGQQYASHVRQLQRGEEPDVRYDFEPYVSNNSWSPIMRTRK 586

  Fly   202 GSM----------SGTTPTTG--------KSRRSSVGIGVEQH---TVDVGQGAERFCATTKVTI 245
            ||.          :|:.|..|        |..|.  |.|.:.|   .:.:        :.|:|.:
Mouse   587 GSFNPGDASGPEAAGSPPEEGGTSEAAPNKDHRG--GRGHQVHKSWPISI--------SDTEVGL 641

  Fly   246 PQDGQGVIRAESTIESLPVIAGNERIGD---GLSSTPRRSVLKEATAPPLTPVNAMAPHV-VAES 306
             ....|.::......|...::.:|.:||   ||          .|:|.....:|.|.|.: ||..
Mouse   642 -DTSSGDLKKFDRTSSSGTMSSSEELGDQEAGL----------VASAFDSADLNGMDPELPVAMP 695

  Fly   307 GTPLQHRPL---MRNHTFSQKTFLRGD-NCVQCQKRIRFGAVGLRCRDCPVRCHIDCRYLLTVSC 367
            ..|.:|..|   .|.|...:   ||.. .|.:|...:.|  .|..|.:|.:.||..|...|.:.|
Mouse   696 SGPFRHVGLSKAARTHRLRK---LRTPAKCRECNSYVYF--QGAECEECCLACHKKCLETLAIQC 755

  Fly   368 VPQTGTPTTKTMTG----YVTDF---APSIAPMIPALIVHCVNEIEARGLTEVGLYRLSSSEREY 425
                   ..|.:.|    :..||   |.|....:|.::..||.|||.|.|...|:||::..:...
Mouse   756 -------GHKKLQGRLQLFGQDFSQAALSTPDGVPFIVKKCVCEIERRALHTKGIYRVNGVKTRV 813

  Fly   426 KALKEQFLRGKATPHLGNTDIYVLCCCVKDFLRSLTEPLIPTSQWKDFANAVQN-----PDTKTA 485
            :.|.:.|..||....|.....:.:...:|.:||.|.||||....:.:.....::     .:.|.|
Mouse   814 EKLCQAFENGKELVELSQASPHDISNVLKLYLRQLPEPLISFRFYHELVGLAKDSLKAEAEAKAA 878

  Fly   486 Q-----------------DMLVKSVKQLPQANRDTLAFLILHFQRIAQCPVVLMPID------NI 527
            .                 ..|.:.::.||..||.||.:|:.|.:||.:     |..|      |:
Mouse   879 SRGRQGGSESEAATLAMVGRLRELMQDLPAENRATLLYLLKHLRRIVE-----MEQDNKMTPGNL 938

  Fly   528 SLIFGPTIVGYSTPDPDQHAIYTEVFT----QKQVMKALL 563
            .::||||::   .|.|....:......    |.:|::.|:
Mouse   939 GIVFGPTLL---RPRPTDATVSLSSLVDYPHQARVIETLI 975

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tum	NP_610912.2	C1	319..367	CDD:237996	13/48 (27%)
		RhoGAP_MgcRacGAP	381..570	CDD:239847	54/222 (24%)
Arhgap45	NP_001334003.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910