DRSC/TRiP Functional Genomics Resources

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Protein Alignment: PDX1 and unpg

Sequence 1:NP_000200.1 Gene:PDX1 HGNCID:6107 Length:283 Species:Homo sapiens
Sequence 2:NP_477146.1 Gene:unpg FlyBaseID:FBgn0015561 Length:485 Species:Drosophila melanogaster

Alignment Length:330 Identity:90/331 (27%)
Similarity:119/331 (36%) Gaps:114/331 (34%)


Human     7 YYA-----ATQLYKDPCAFQRGPAPEFSASPPACLYMGRQPPPPPPHPFPGALGALEQGSPPDI- 65
            |:|     .|.|....|.....||...:|..|..   ..||.||||||   ...|||:..||.: 
  Fly    92 YFAQNHERLTHLIAGGCYLPSSPAGHPAAQQPQA---QAQPQPPPPHP---PTHALEKQLPPTLP 150

Human    66 SPYEVPPLADDPAVAHLH------------------HHLPAQLALPH-PPAGPFPEG-AEPGV-- 108
            .|.:...|..:||.|.:.                  |.|.....|.| ..||...|. |.||:  
  Fly   151 HPLDTRFLPFNPAAAGVAPTDLSYRRLAELMNQDYVHSLSVHARLQHMAAAGRMHEDQANPGMAQ 215

Human   109 LEEPNRVQLPFPWMKSTKAHA--------------------------------WKGQW---AGGA 138
            |:||...|......|| .:|:                                :.|:.   ..||
  Fly   216 LQEPTPPQAHSSPAKS-GSHSPMEPALDVGMDEDFECSGDSCSDISLTMSPRNYNGEMDKSRNGA 279

Human   139 YAAEPEE--------------------------------NKRTRTAYTRAQLLELEKEFLFNKYI 171
            |.....|                                ::|.|||:|..||||||:||...||:
  Fly   280 YTNSDSEDCSDDEGAQSRHEGGGMGGKDSQGNGSSSNSKSRRRRTAFTSEQLLELEREFHAKKYL 344

Human   172 SRPRRVELAVMLNLTERHIKIWFQNRRMKWKKEEDKKRGGGTAVGGGGVAEPEQDCAVTSGEELL 236
            |...|.::|..|.|:|..:||||||||.|||    :.:.|.|:.|.|       ....|||.:::
  Fly   345 SLTERSQIATSLKLSEVQVKIWFQNRRAKWK----RVKAGLTSHGLG-------RNGTTSGTKIV 398

Human   237 ALPPP 241
             :|.|
  Fly   399 -VPIP 402

Known Domains:


GeneSequenceDomainRegion External IDIdentity
PDX1NP_000200.1 Transactivation domain. {ECO:0000250} 13..73 20/61 (33%)
Antp-type hexapeptide 118..123 0/5 (0%)
Homeobox 149..202 CDD:278475 30/53 (57%)
Nuclear localization signal. {ECO:0000250} 197..203 5/6 (83%)
unpgNP_477146.1 Homeobox 324..375 CDD:278475 29/51 (57%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
eggNOG 1 0.900 E2759_KOG0489
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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