Protein Alignment CG4676 and ZDHHC22

DIOPT Version :10

• Sequence 1: NP_610853.1
• Gene: CG4676 / 36465
• FlyBaseID: FBgn0033815
• Length: 284
• Species: Drosophila melanogaster
• Sequence 2: NP_777636.2
• Gene: ZDHHC22 / 283576
• HGNCID: 20106
• Length: 263
• Species: Homo sapiens
• Alignment Length: 292
• Identity: 78/292 - (26%)
• Similarity: 116/292 - (39%)
• Gaps: 75/292 - (25%)

  Fly     1 MMILRSWDRVKPRSISDFACFLLVAVFVPVTYIFHVTIVMPELF---AIGGIWYTLLWLASLFLI 62
            |:.||..:.|.|      |.||.:::   ||::..:.:.:|.:.   |...::...|...:|||.
Human     1 MLALRLLNVVAP------AYFLCISL---VTFVLQLFLFLPSMREDPAAARLFSPALLHGALFLF 56

  Fly    63 FNITSNMLA--CMLVDTSIRKELLKPPLDAAQLARWHSCQDC---QTLVPPRSWH-CEVCNVCVL 121
              :::|.|.  .:::..|        |.|..      :||..   :|..|..|.| |.||....|
Human    57 --LSANALGNYVLVIQNS--------PDDLG------ACQGASARKTPCPSPSTHFCRVCARVTL 105

  Fly   122 KRDHHCRFTCCCIGHHNYRYFFYYLVYMIIGSLAAAIMESIYLWHLHLDIYWRWSTLFTI-FA-P 184
            :.||||.||..|||..|.|.|..:.:|..:..|.:.:....|:           |.:.:| || |
Human   106 RHDHHCFFTGNCIGSRNMRNFVLFCLYTSLACLYSMVAGVAYI-----------SAVLSISFAHP 159

  Fly   185 VVSLMLSP-SWESFY------------LVIY-----DLTLLGFAISSLLLVFHWSI---FKSGSV 228
            :..|.|.| |...|:            |::|     .|...||....|||:.....   .:.|..
Human   160 LAFLTLLPTSISQFFSGAVLGSEMFVILMLYLWFAIGLACAGFCCHQLLLILRGQTRHQVRKGVA 224

  Fly   229 TRERGTRKYDRGLRGNLEMVLGKRMHLTWLSP 260
            .|.|..||       ||:.|.|||..|..|.|
Human   225 VRARPWRK-------NLQEVFGKRWLLGLLVP 249

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4676	NP_610853.1	DHHC	99..232	CDD:396215	45/159 (28%)
ZDHHC22	NP_777636.2	DHHC	92..218	CDD:396215	39/136 (29%)