Protein Alignment Dp and Tfdp1

DIOPT Version :10

• Sequence 1: NP_477039.1
• Gene: Dp / 36461
• FlyBaseID: FBgn0011763
• Length: 445
• Species: Drosophila melanogaster
• Sequence 2: NP_001423505.1
• Gene: Tfdp1 / 361178
• RGDID: 1560344
• Length: 410
• Species: Rattus norvegicus
• Alignment Length: 387
• Identity: 173/387 - (44%)
• Similarity: 220/387 - (56%)
• Gaps: 61/387 - (15%)

  Fly    91 IPKTEAGTTYTTVSAQKTSG------------AGSGHYDLPLKGDRYVKFTPNPIKMKSKLHAIQ 143
            :||| .|.:...::.|...|            .||.|             |||       .|.:.
  Rat    47 LPKT-FGQSNVNITQQVVIGTPQRPAAANTIVVGSPH-------------TPN-------THFVS 90

  Fly   144 SNSLHSMSASSSSVQRKRKPDKAGKGLRHFSMKVCEKVEEKGKTTYNEVADDLVSEEMKNNAYDN 208
            .|.. |.|:..|:.:|.||.:|.|||||||||||||||:.||.|:||||||:||:|   .:|.||
  Rat    91 QNQT-SDSSPWSAGKRNRKGEKNGKGLRHFSMKVCEKVQRKGTTSYNEVADELVAE---FSAADN 151

  Fly   209 NC-------DQKNIRRRVYDALNVLMAINVISKDKKEIRWIGLPANSTETFLALEEENCQRRERI 266
            :.       ||||||||||||||||||:|:|||:||||:|||||.||.:....||.|..:|.|||
  Rat   152 HILPNESAYDQKNIRRRVYDALNVLMAMNIISKEKKEIKWIGLPTNSAQECQNLEVERQRRLERI 216

  Fly   267 KQKNEMLREMIMQHVAFKGLVERNKRNESQG-VVPSPNASIQLPFIIVNTHKSTKINCSVTNDKS 330
            |||...|:|:|:|.:|||.||:||::.|.|. ..|.||:.|.||||||||.:.|.|:||::|||.
  Rat   217 KQKQSQLQELILQQIAFKNLVQRNRQAEQQARRPPPPNSVIHLPFIIVNTSRKTVIDCSISNDKF 281

  Fly   331 EYIFKFDKTFEMHDDIEVLKRMGFLLGLDKGECTPENIERVKSWVPPNLAKYVEAYGTGKTG--- 392
            ||:|.||.|||:|||||||||||...||:.|.|:.|:::..:|.||..|..||.....|..|
  Rat   282 EYLFNFDNTFEIHDDIEVLKRMGMACGLESGSCSAEDLKVARSLVPKALEPYVTEMAQGSIGGVF 346

  Fly   393 ---------ENMYESDDEDNEFNGYLESANESQGFAQHSAQHTTDGEFKLEMDDDELDDDID 445
                     .....:.|..|..:|.|  |..|.|.....::..|...:..|.|||  |||.:
  Rat   347 VTTTGSTSNGTRLSASDLSNGADGML--ATSSNGSQYSGSRVETPVSYVGEDDDD--DDDFN 404

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dp	NP_477039.1	E2F_TDP	167..243	CDD:460530	57/82 (70%)
		coiled coil	248..294	CDD:271217	22/45 (49%)
		DP	255..386	CDD:462601	72/131 (55%)
Tfdp1	NP_001423505.1	E2F_TDP	112..193	CDD:460530	57/83 (69%)
		coiled coil	198..244	CDD:271217	22/45 (49%)
		DP	200..338	CDD:462601	72/137 (53%)