Protein Alignment Dp and Tfdp2

DIOPT Version :10

• Sequence 1: NP_477039.1
• Gene: Dp / 36461
• FlyBaseID: FBgn0011763
• Length: 445
• Species: Drosophila melanogaster
• Sequence 2: NP_001395472.1
• Gene: Tfdp2 / 211586
• MGIID: 107167
• Length: 447
• Species: Mus musculus
• Alignment Length: 252
• Identity: 47/252 - (18%)
• Similarity: 82/252 - (32%)
• Gaps: 68/252 - (26%)

  Fly    94 VRECADHSDEHAHCPGNSGTILAAHGNCSNTEFSCRSSECIPADQVCDGQEDCPDGTDETQPLCS 158
            :::|....|  ..||..|..:..:..:...: |....|..:..:::......||....:..|  |
Mouse    31 IKDCFQALD--LGCPDESIQLQISQQHLDKS-FRKAVSLIVAVEKLWQLPMSCPWSFQDEDP--S 90

  Fly   159 LVFCPSFSFRCSYGACIGGYSKCDGVVDCRDGSDEDELLCGRPFPSTTPRPVTTAPTSSTTTTST 223
            ..|  ||.|.             :..|.|....|:|.|:|..|......|
Mouse    91 TFF--SFIFE-------------EEPVLCDSWDDDDLLVCDVPIRQLHCR--------------- 125

  Fly   224 TTVAPVVKVTGPPGSCVVPSAP-------PNGRFVLDETAQTVPILAGEFIENYNSVHVVCGDKY 281
                    :......|:|.|.|       .||:.:..:...::..:.||  .:.:.:.|..|
Mouse   126 --------LRDEQQKCLVLSDPCELKALHLNGQNISQQVVFSMSFVQGE--TSNDKIPVALG--- 177

  Fly   282 TLKGA---ATIVCLDG------EWLEP--FPVCEKYCSEIPINGITIEPFCEYQRRQ 327
             |||.   .:.|..||      |.::|  :|. :|.......|.|.::...|::..|
Mouse   178 -LKGKNLYLSCVMKDGTPTLQLESVDPKQYPK-KKMEKRFVFNKIEVKTKVEFESAQ 232

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dp	NP_477039.1	E2F_TDP	167..243	CDD:460530	11/75 (15%)
		coiled coil	248..294	CDD:271217	9/48 (19%)
		DP	255..386	CDD:462601	18/84 (21%)
Tfdp2	NP_001395472.1	E2F_TDP	128..209	CDD:460530	19/87 (22%)
		coiled coil	214..260	CDD:271217	4/19 (21%)
		DP	216..354	CDD:462601	4/17 (24%)