Protein Alignment AQP and AQP12A

DIOPT Version :10

• Sequence 1: NP_523728.1
• Gene: AQP / 36456
• FlyBaseID: FBgn0033807
• Length: 276
• Species: Drosophila melanogaster
• Sequence 2: XP_054197901.1
• Gene: AQP12A / 375318
• HGNCID: 19941
• Length: 521
• Species: Homo sapiens
• Alignment Length: 265
• Identity: 72/265 - (27%)
• Similarity: 121/265 - (45%)
• Gaps: 22/265 - (8%)

  Fly     6 LGISALFMVGCCALAQIARVISRRLVTREGLVPILINEAIAAAELCACCFELIIV------ADNF 64
            |.:|..|.....||.:.||..|:.|:. .|...:...||:.|.:|.||..|:..:      |.:|
Human     4 LNVSLSFFFATFALCEAARQASKALLP-VGAYEVFAREAVGAVQLGACFLEMRTLVELGPWAGDF 67

  Fly    65 GVSMYAVCLFLLTIWWGRVWGDASACPYTHMEDVVEGRTSFKEMALRSWAELMGGCCVYRVVQVF 129
            |..:....||||.:..|.....|||.|...:::.:....|.....|:..|:.:|......:.::.
Human    68 GPDLLLTLLFLLFLAHGVTLDGASANPTVSLQEFLMAEESLPGTLLKLAAQGLGMQAACTLTRLC 132

  Fly   130 WWLELAETH--RGRAFEACNADMQVSPYLGAVIEGVATLLCRLASKTISEKEPRFGSYIDSFIGT 192
            |..||::.|  :....::|::.::.|...||::|........|....:....|.:     |....
Human   133 WAWELSDLHLLQSLMAQSCSSALRTSVPHGALVEAACAFCFHLTLLHLRHSPPAY-----SGPAV 192

  Fly   193 SLVVAVYAFNYVLLAAFNFSGGYFNPVLATALKWGCRGHTHLEHIIVYWIGACAGAV---LSIPV 254
            :|:|.|.|:     .|..|:..:|||.||.::.:.|.|||.||::.|||:|...|||   |::..
Human   193 ALLVTVTAY-----TAGPFTSAFFNPALAASVTFACSGHTLLEYVQVYWLGPLTGAVTACLTVDT 252

  Fly   255 FKVPA 259
            ..||:
Human   253 VPVPS 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AQP	NP_523728.1	None
AQP12A	XP_054197901.1	GlpF	<152..248	CDD:440345	31/105 (30%)