Protein Alignment AQP and AQP11

DIOPT Version :10

• Sequence 1: NP_523728.1
• Gene: AQP / 36456
• FlyBaseID: FBgn0033807
• Length: 276
• Species: Drosophila melanogaster
• Sequence 2: NP_766627.1
• Gene: AQP11 / 282679
• HGNCID: 19940
• Length: 271
• Species: Homo sapiens
• Alignment Length: 259
• Identity: 61/259 - (23%)
• Similarity: 108/259 - (41%)
• Gaps: 27/259 - (10%)

  Fly     4 TALGISALFMVGCCALAQIARVISRRLVTREGLVPI---LINEAIAAAELCACCFELIIVADNFG 65
            |:||:    |:....|..:|||::|:.:.|    |:   .:.|.:|..:||.|..||.::::...
Human    16 TSLGL----MLSVVLLMGLARVVARQQLHR----PVAHAFVLEFLATFQLCCCTHELQLLSEQHP 72

  Fly    66 V--SMYAVCLFLLTIWWGRVWGDASACPYTHMEDVVEGRTSFKEMALRSWAELMGGCCVYRVVQV 128
            .  :.....::..::..|......|:.|...|..::.|..|.:..|:|..|:|:...|.......
Human    73 AHPTWTLTLVYFFSLVHGLTLVGTSSNPCGVMMQMMLGGMSPETGAVRLLAQLVSALCSRYCTSA 137

  Fly   129 FWWLELAETHRGRAFEACNADMQVSPYLGAVIEGVATLLCRLASKTISEKEPRFGSYIDSFIGTS 193
            .|.|.|.:.|......||...::|......:.|.|.:.|...|.....|            :.|.
Human   138 LWSLGLTQYHVSERSFACKNPIRVDLLKAVITEAVCSFLFHSALLHFQE------------VRTK 190

  Fly   194 LVVAVYA--FNYVLLAAFNFSGGYFNPVLATALKWGCRGHTHLEHIIVYWIGACAGAVLSIPVF 255
            |.:.:.|  ..:::.|..:.:|..|||.||.:|.:.|......:..||||:....|.:|.|.:|
Human   191 LRIHLLAALITFLVYAGGSLTGAVFNPALALSLHFMCFDEAFPQFFIVYWLAPSLGILLMILMF 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AQP	NP_523728.1	None
AQP11	NP_766627.1	MIP	46..257	CDD:444743	50/221 (23%)
		NPC. /evidence=ECO:0000250|UniProtKB:Q96PS8	99..101		0/1 (0%)
		NPA. /evidence=ECO:0000250|UniProtKB:Q96PS8	216..218		1/1 (100%)