Protein Alignment Su(z)2 and Psc

DIOPT Version :10

• Sequence 1: NP_001260933.1
• Gene: Su(z)2 / 36432
• FlyBaseID: FBgn0265623
• Length: 1396
• Species: Drosophila melanogaster
• Sequence 2: XP_001237808.3
• Gene: Psc / 4576272
• VectorBaseID: AGAMI1_010994
• Length: 1706
• Species: Anopheles gambiae
• Alignment Length: 1590
• Identity: 385/1590 - (24%)
• Similarity: 581/1590 - (36%)
• Gaps: 426/1590 - (26%)

  Fly    12 SNAAMDAASPAS--RDVR----QFHDLITCRLCRGYMIDPTTVDYCYHTYCRSCILKHLLRAVYC 70
            :.|...:|.|.|  |..|    ..|..|||.||:||:||.||:..|.|::|.|||:|||....||
Mosquito    70 AKAMFGSAGPLSPYRPSRVKLGSVHPCITCHLCKGYLIDATTIVECLHSFCHSCIMKHLRTEQYC 134

  Fly    71 PECKASGGKEINEL--NLKSDDTLRSLIYKLVPGLYQRECKELADFKEQHD-----LVDEQTTDE 128
            |:|:..    ||:.  |:|.|.||::::|||||.||:.|.:....|...|.     ...||..::
Mosquito   135 PQCEMM----INKAKPNIKPDATLQAIVYKLVPRLYENELRRRRAFYRLHPEMATVATPEQRGED 195

  Fly   129 PEF--FTTTELISLSLEYHPAMLHQCGPGEVPPTIYLQCAAGLPVELLKRFLCSKYNIETDNGLV 191
            .|:  |:..|.|||||||....|.:... |:....||.|.|...:.|||:|:..||.|......|
Mosquito   196 TEYLIFSPNEKISLSLEYAEKELAEDNE-ELLKAKYLLCPAVFSIALLKKFIIYKYGISERQFCV 259

  Fly   192 EVEVTYKDEVLPTNFTLMDVAYCYNWSRESPMAFCYRILLYDNEQTKNDENNLSR---------- 246
            |:....|..:||..:|||||||.|.|.|::||.:.|||...::...:..|..|.|
Mosquito   260 EIMYKVKTIILPDYYTLMDVAYIYTWKRDAPMKYYYRIRTTESNPVELPEVALRRSPSLVTALPA 324

  Fly   247 ----INQDIEPEHSVRRSKSAKSVTFAEDLESEIDSGSPRSKVRCKTPPKVSPSSKNKRLTSSKR 307
                ::::.:.|:.||..:     ..:|...:|.||.|..|.......|:...|   |..|::..
Mosquito   325 QRPSVDEEDDKENRVRLDR-----IVSEAASNESDSSSSSSSNAIANTPRADAS---KPPTAAPV 381

  Fly   308 EAEPESPVSNFKSLRSNDMRYSDYAVSKVKSEPEQEQFLLPREREQQPLE--ANTNIVVSI---- 366
            ...||||.:                       |.|     ||:.|...|:  .|.|..|||
Mosquito   382 TPAPESPAT-----------------------PTQ-----PRKNESIKLKIGLNKNTYVSILQSP 418

  Fly   367 ---------------------PPSQLRKSYVDAEDFELKTANRKGVGHLPKLKIELNSMKSKLSM 410
                                 |.|:..||....:..:.|...:..:..|.:::.....:|.|:.
Mosquito   419 QPDEPSTHSSSSSSSSSSASSPGSEGAKSSSSHKSEKSKRKRKDALATLQQMEENSRELKFKIE- 482

  Fly   411 PLSAGPRLEDT------SCSLSCSAQQLDLETYAKNIGLKPIEQPLQQSASNPDSKYSPNASPMS 469
                  :::||      |.|...||:.   ..:.:.:.|.|.:..|....|.|.:...|..|...
Mosquito   483 ------QMKDTGLVGSKSKSGKSSAKH---HQHQQQLALVPYKVELSAGLSQPSAVPEPERSDSK 538

  Fly   470 SCSSSTNGSSSSLGTADASTSTSTSSSHRKRKKKHSKEPKDANGKRKKLHAEISSQTDGKMKVKI 534
            ...|:.|||:|:.|         :|.::.|.|.|.| .|:|  ||:::.|
Mosquito   539 RLHSAKNGSNSASG---------SSPAYCKLKIKKS-SPED--GKQQQHH--------------- 576

  Fly   535 TAKPNHKLDFKRSHSLASGELDLQKLKLDSTSTSEALNRTL--GEEARSINSLVVGGAPTPPPTP 597
                :|      .|.:.        ||:|..| .|....||  |...:|..|:    .|:|||.|
Mosquito   577 ----HH------HHPIV--------LKIDQRS-PEMATATLKFGMPRKSEKSM----TPSPPPLP 618

  Fly   598 TAEPEQQQQQQQQQQQPQQQQQQQQQQQQQQQFVVLPKIKDLTLPTSPPLPPSLFKAYTPSTTPT 662
            .:.|          ..|..:|:...::.|......|..||.....:||....:  .|.|.:||.|
Mosquito   619 PSPP----------TPPSPKQKFADEKSQFLNSFQLTPIKPSEQSSSPSKTSA--AATTTATTTT 671

  Fly   663 APHTV-----AGGKPKQQQQQMPQQPQAVLQQSLAKTNPAKPPLSSNNNRKPNSGHFAVPQAPTH 722
            .|..|     ||.|.......:|  |.|      |.||...||.|:...            ..|.
Mosquito   672 PPAAVESVAPAGKKSPTSTSSVP--PVA------APTNSTSPPASNGTG------------TTTK 716

  Fly   723 RNMYHMQRYQSTPSSIASAANKMPKRS----MSLDESHPAKQARLSQAQAMASSYAAKLHMQTSN 783
            |.    .:..|:...:..:..|.||.|    .::.|...|:..| |.::.:......|....|:.
Mosquito   717 RK----AKDASSGGGVPRSGPKKPKLSNDEIKAIVEKTVAENIR-SPSEHIVPPIFLKPKPPTTT 776

  Fly   784 QAKSQAAAFLPNPQMRSYGLPDLGSKPTLPMLCPASSSSQ--VTITPRPRATPSIYSFSEPNIHV 846
            .|  .||:..|:|.:.|...|.....|:     |...|.:  |..||.|...|.|.|.:......
Mosquito   777 TA--AAASGQPSPPLPSSSAPTKAKDPS-----PKRDSPRPFVFKTPPPPPPPPIVSANNIPAVK 834

  Fly   847 PALEIVRLPVNKQSAGGKGLTMP-PLSPPATSSARLMGPPAALPKHAGHGHGAAKRSCQMPTMPM 910
            |:.:::..||.::.|       | |:.|..|::     |..|:|:       ..:...:.||.|.
Mosquito   835 PSQQVLPAPVPQKPA-------PVPIRPALTTA-----PKPAVPQ-------VPQTHIRKPTAPT 880

  Fly   911 PLPLPLPMPMTTIPAIVKSPPL-------------------SVALSGQRNNKG---NSSNSNAYR 953
            .||...|.....:.:  .|||.                   |||....|..||   ..:.||...
Mosquito   881 KLPTSAPAGTAGVKS--ASPPAQQPLSNGSQQQQASNATTHSVAAGANRQQKGLELKRAQSNPSI 943

  Fly   954 TSPPALINLRNTAAPQHSFPSKSSPKVEANSKKSPPAAGCQGKTNGTAALDKSKTSLR------- 1011
            ..||          ||.|.|..:.|:....||..|.......|..|.....|..|::.
Mosquito   944 NIPP----------PQTSAPPVTVPRDTEISKLRPEDLKKNQKVYGPEQQQKPNTTMEATGASFA 998

  Fly  1012 ----EFRPAVQSAVTATATTSVTTAAGAGAGAGTGT--------GTAL--AKDADILDLSANPGR 1062
                :..|...|:..|....:.|.::|: |.||.||        ..||  :|.|.....:..|..
Mosquito   999 VPGPKAAPKPSSSSAAVPAGNATKSSGS-APAGQGTKARPVNYLNYALLNSKAAAAGSRTPIPSY 1062

  Fly  1063 SNNDAKLAPNSPPAGNNNNNNNN----------NNNNNNNNNNNNNNSTS---NSLEAALNKIKQ 1114
            |::....:|:||....|.|.::.          |::..|..|:....|||   :|..|
Mosquito  1063 SSSSPSYSPDSPQYSPNLNFSSKQFKYANPLAYNSHLQNMLNDRRTGSTSPPGSSTSA------- 1120

  Fly  1115 NISANSNGGP-----STTSGSNSNG------TTNGDDLQNL------HMLSESATAREKISIKAA 1162
             |.|:|...|     :|||.::.|.      :...||.:..      .:||.:..|........:
Mosquito  1121 -IPASSPSPPQDRPAATTSNASGNKRPASALSPTADDKKQQPPEKQPALLSAAVAAPNPADKFPS 1184

  Fly  1163 SSGNGSGST----SSSSAKPKNANALVRPQNASVRSIPN------------PSALAF-------- 1203
            ...:|...|    ...:|:.||.|..::.....:|::|.            ||:...
Mosquito  1185 GIPDGLSVTLATDDDDAARIKNVNKQLKNNFIEIRALPEVPITEVKLPLPLPSSSTTTTASKPGR 1249

  Fly  1204 RNQPAAASTAASISKPLTVRAEEKPKVSTSNPGSLSPT-NTSSSSSSSSSGSSGC---------- 1257
            |..|..|:.||  ..|.|:.....|:.| |:|...:|| :.::|:...:|.||..
Mosquito  1250 RTPPGKAAAAA--GSPGTLSGSPMPRKS-SSPSVAAPTYSVAASAPPKTSVSSAAPPPANRPADA 1311

  Fly  1258 ------------SAATSPRAMTKKPTTIDQVAANLNIRAEAKAAALAEEAPPVLSSNAAKSPELA 1310
                        |.::|.:..:|.|.|:..|:     |........:...|||.|.|..|.|...
Mosquito  1312 LQRKIIDLIDKPSPSSSGKTSSKPPPTMPPVS-----RPSTPKGGGSGSFPPVNSGNKFKLPNAT 1371

  Fly  1311 KTTTA---------VALRPE------PKETPITVSAASTLLTIP---SAVSSVSAVP-------- 1349
            .....         |.|.|:      ||..|...|.||: .|:|   |:.||.|.:|
Mosquito  1372 VNENGTLKLNNYREVDLIPKGAAASGPKSAPSPPSGASS-RTMPPQTSSASSKSIMPIAPKPSSS 1435

  Fly  1350 --ETMA------KPPVQIANAPVASSAXSQ 1371
              ::.|      .||:|  .:|.|:|...|
Mosquito  1436 QLQSFANGRMAMSPPIQ--RSPTATSGYQQ 1463

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Su(z)2	NP_001260933.1	RING-HC_PCGF5	23..117	CDD:438395	44/101 (44%)
		RAWUL_PCGF2_like	137..228	CDD:340602	37/90 (41%)
Psc	XP_001237808.3	None