Protein Alignment Su(z)2 and Pcgf2

DIOPT Version :10

• Sequence 1: NP_001260933.1
• Gene: Su(z)2 / 36432
• FlyBaseID: FBgn0265623
• Length: 1396
• Species: Drosophila melanogaster
• Sequence 2: NP_033571.1
• Gene: Pcgf2 / 22658
• MGIID: 99161
• Length: 342
• Species: Mus musculus
• Alignment Length: 347
• Identity: 100/347 - (28%)
• Similarity: 155/347 - (44%)
• Gaps: 45/347 - (12%)

  Fly    26 VRQFHDLITCRLCRGYMIDPTTVDYCYHTYCRSCILKHLLRAVYCPECKASGGKEINELNLKSDD 90
            :.:.:..:.|.||.||.||.||:..|.|::|::||:::|....|||.|.....|....|:::||.
Mouse     9 ITELNPHLMCALCGGYFIDATTIVECLHSFCKTCIVRYLETNKYCPMCDVQVHKTRPLLSIRSDK 73

  Fly    91 TLRSLIYKLVPGLYQRECKELADFKEQHDLVD----------EQTTDEPEFFTTTELISLSLEYH 145
            ||:.::|||||||::.|.|...||...:.|.:          |....|.......|::|||:|::
Mouse    74 TLQDIVYKLVPGLFKDEMKRRRDFYAAYPLTEVPNGSNEDRGEVLEQEKGALGDDEIVSLSIEFY 138

  Fly   146 PAM--------LHQCGPGEVPPT--IYLQCAAGLPVELLKRFLCSKYNIETDNGLVEVEVTYKDE 200
            ..:        |.:.|.|:...|  .:|:|.|.:.|..|.:||.:|.::.:.   .:||:.|:||
Mouse   139 EGVRDREEKKNLTENGDGDKEKTGVRFLRCPAAMTVMHLAKFLRNKMDVPSK---YKVEILYEDE 200

  Fly   201 VLPTNFTLMDVAYCYNWSRESPMAFCYRI------LLYDNEQTKNDENNLSRINQDIEPEHSVRR 259
            .|...:||||:||.|.|.|..|:...||:      |......|.::..|.|..::.    .||
Mouse   201 PLKEYYTLMDIAYIYPWRRNGPLPLKYRVQPACKRLTLPTVPTPSEGTNTSGASEC----ESV-- 259

  Fly   260 SKSAKSVTFAEDLESEIDS------GSPRSKVRCKTPPKVSPSSKNKRLTSSKREAEPESPVSNF 318
            |..|.|........|.:.|      |||.|    ..||...|:|.....|::..........||.
Mouse   260 SDKAPSPATLPATSSSLPSPATPSHGSPSS----HGPPATHPTSPTPPSTAAGTTTATNGGTSNC 320

  Fly   319 KSLRSNDMRYSDYAVSKVKSEP 340
            ....|:..|.....|:.....|
Mouse   321 LQTPSSTSRGRKMTVNGAPCPP 342

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Su(z)2	NP_001260933.1	RING-HC_PCGF5	23..117	CDD:438395	36/90 (40%)
		RAWUL_PCGF2_like	137..228	CDD:340602	32/100 (32%)
Pcgf2	NP_033571.1	RING-HC_PCGF4	5..101	CDD:438394	36/91 (40%)
		Nuclear localization signal. /evidence=ECO:0000255	81..95		8/13 (62%)
		RAWUL_PCGF2	130..228	CDD:340684	32/100 (32%)
		PHA03247	<222..304	CDD:223021	22/91 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	237..342		24/114 (21%)