DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17019 and APD1

DIOPT Version :9

Sequence 1:	NP_001286365.1	Gene:	CG17019 / 36425	FlyBaseID:	FBgn0033783	Length:	700	Species:	Drosophila melanogaster
Sequence 2:	NP_973633.2	Gene:	APD1 / 818397	AraportID:	AT2G38185	Length:	447	Species:	Arabidopsis thaliana

Alignment Length:	275	Identity:	53/275 - (19%)
Similarity:	91/275 - (33%)	Gaps:	100/275 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   487 LENSQMSEEDIKRELQEFLTYLEQRTKSVDASDADSHAVSPLSVDAI------------------ 533
            :|.|.|.:.:|::....:|.....::|.|:.:..|...:: :.|.|:
plant   208 IEGSGMIQLEIRKSSSYYLAVANLKSKDVEVTTTDQVELN-IDVKAVLYDTKQSFYNCNFSNGEC 271

  Fly   534 ---SVAAGGRSPDMPITPTIEFSPTQDEDIRWDDDEGIHVYAAPSDFEPTAG---------IDSR 586
               :::..|.|       .:..||...:.:..:|:..|.....|.:.....|         :..:
plant   272 TFNAMSLVGNS-------VVVTSPAASQGVSIEDEWYIRFSYQPREIAYVIGTGVVICFMLVAIQ 329

  Fly   587 FVN---------------------LEDFEDLKDLEGLTVKQLKEVLMLHRVDYKGCCEKQELLDR 630
            |.|                     |.|    ||.:|.::               |.|:.....|
plant   330 FCNRFQCSGGEGHLTEDDSARTRLLAD----KDDDGSSM---------------GSCDDSYAND- 374

  Fly   631 VSRLWKTMRECPAVEKLATD--------ELCKICMDAPIECVFLECGHMATCTSCGKVLNE---- 683
                     :....|.:..|        .||.||.|.|.:|.||.|||..:|..||..:.|
plant   375 ---------DADLEEFMGNDGEASNRSRRLCAICFDVPRDCFFLPCGHSVSCYECGTTMQEADGS 430

  Fly   684 CPICRQYIVRVVRFF 698
            |||||:.:.:|.|.:
plant   431 CPICRRKMKKVKRIY 445

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17019	NP_001286365.1	FYVE_CARP	1..42	CDD:277289
CG17019	NP_001286365.1	zf-C3HC4_3	650..694	CDD:290631	22/55 (40%)
APD1	NP_973633.2	DUF4792	120..187	CDD:292659
		DUF4793	217..326	CDD:292660	15/116 (13%)
		zf-C3HC4_3	392..441	CDD:290631	21/48 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	53	1.000	Domainoid score	I4202
eggNOG	1	0.900	-	-		E1_KOG4275
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3123
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.810