Protein Alignment CG17019 and Rnf34

DIOPT Version :9

• Sequence 1: NP_001286365.1
• Gene: CG17019 / 36425
• FlyBaseID: FBgn0033783
• Length: 700
• Species: Drosophila melanogaster
• Sequence 2: NP_085041.1
• Gene: Rnf34 / 80751
• MGIID: 2153340
• Length: 376
• Species: Mus musculus
• Alignment Length: 709
• Identity: 137/709 - (19%)
• Similarity: 197/709 - (27%)
• Gaps: 405/709 - (57%)

  Fly     3 CESCGVEFTVFRRKRACFDCKRYYCANCIAS----RRCKRCSVFAQRPLSRTDLLKLKPKDLIFY 63
            |::||:.|:|||:|..|.|||:.:|:.|..|    |||..|.:..:....|..|::||.|||..|
Mouse    62 CKACGLSFSVFRKKHVCCDCKKDFCSLCSVSQENLRRCSTCHLLQETAFQRPQLMRLKVKDLRQY 126

  Fly    64 LQSKHISTEGCLEKEELVGLVLTHVAQVDRSRGSNASSNSPGRGQANPIDSLKQSCQNFFSNLSD 128
            |..::|.|:.|.|||:||.|||.|                .|.|..:.:||         |:|:.
Mouse   127 LLLRNIPTDTCREKEDLVDLVLCH----------------RGLGSGDDLDS---------SSLNS 166

  Fly   129 NISDSLASFDSKVTTKPPESRQPEVPTHIFEQPRVSTREIPTYASAVNGGPQHVHVQQQATTTNG 193
            :.|.:.:.|...:.
Mouse   167 SRSQTSSFFTQSLF--------------------------------------------------- 180

  Fly   194 GSQSSSSPSTSTQSSNNRDASSSSQAHVAHQEARNEEQEDAQSKSDCECSDEEIMATFSERVSIS 258
               |:.:|.::|.||                                  ...|:|
Mouse   181 ---SNYTPPSATVSS----------------------------------FQGELM---------- 198

  Fly   259 LKTDTSGRRVNAAAEPSPVDLANVDNGPAGNTAPSPGCSKPGSSSSKADASSQSSFEELGAIGGI 323
                                                  .:.|:..|:..|..||..
Mouse   199 --------------------------------------DRDGAFRSEVLAQVQSEI--------- 216

  Fly   324 SDESKANTDTNSSHLDQWQVLEVNRIEAVEETPTTSAADEILEVTLRSRPAVEGDDSEMGESTQA 388
               :.||||.:....|                                    :.||.|
Mouse   217 ---ASANTDDDDDDDD------------------------------------DDDDDE------- 235

  Fly   389 LNVNQRPANPSPAFYPAVPQRTKKVTRRRSDGYLNRRYHSSDDESPVAPGGPGLSLGLSTLSEHP 453
                                                   ..|||.......||||
Mouse   236 ---------------------------------------DDDDEQEEEEQNPGLS---------- 251

  Fly   454 EHGLHPHSHRQSCQRCGKNKTNIRRHVEKMRRHLENSQMSEEDIKRELQEFLTYLEQRTKSVDAS 518
                             |.|..
Mouse   252 -----------------KKKAR------------------------------------------- 256

  Fly   519 DADSHAVSPLSVDAISVAAGGRSPDMPITPTIEFSPTQDEDIRWDDDEGIHVYAAPSDFEPTAGI 583
                                                                             
Mouse   257 ----------------------------------------------------------------- 256

  Fly   584 DSRFVNLEDFEDLKDLEGLTVKQLKEVLMLHRVDYKGCCEKQELLDRVSRLW-------KTMREC 641
                .:|.|...|:::||::|:||||:|..:.|:|.|||||.||:::|:||:       |:..|.
Mouse   257 ----ASLSDLSSLEEVEGMSVRQLKEILARNFVNYSGCCEKWELVEKVNRLYKENEENQKSYGER 317

  Fly   642 PAVEKLATDELCKICMDAPIECVFLECGHMATCTSCGKVLNECPICRQYIVRVVRFFRA 700
            ..::....|.||:|||||.|:||.||||||.|||.|||.::||||||||:||.|..|::
Mouse   318 MQLQDEEDDSLCRICMDAVIDCVLLECGHMVTCTKCGKRMSECPICRQYVVRAVHVFKS 376

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17019	NP_001286365.1	FYVE_CARP	1..42	CDD:277289	19/42 (45%)
		zf-C3HC4_3	650..694	CDD:290631	32/43 (74%)
Rnf34	NP_085041.1	FYVE_CARP1	59..105	CDD:277308	19/42 (45%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	216..256		17/160 (11%)
		zf-C3HC4_3	325..367	CDD:290631	30/41 (73%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836768
Domainoid	1	1.000	150	1.000	Domainoid score	I4376
eggNOG	1	0.900	-	-		E1_KOG4275
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	226	1.000	Inparanoid score	I3475
Isobase	1	0.950	-	0	Normalized mean entropy	S7198
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002853
OrthoInspector	1	1.000	-	-		otm42320
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR14879
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4872
SonicParanoid	1	1.000	-	-		X1893
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	13	12.830