Protein Alignment CG17019 and Rffl

DIOPT Version :10

• Sequence 1: NP_610827.2
• Gene: CG17019 / 36425
• FlyBaseID: FBgn0033783
• Length: 700
• Species: Drosophila melanogaster
• Sequence 2: XP_006534053.2
• Gene: Rffl / 67338
• MGIID: 1914588
• Length: 432
• Species: Mus musculus
• Alignment Length: 718
• Identity: 151/718 - (21%)
• Similarity: 197/718 - (27%)
• Gaps: 421/718 - (58%)

  Fly     3 CESCGVEFTVFRRKRACFDCKRYYCANCIAS-----RRCKRCSVFAQRPLSRTDLLKLKPKDLIF 62
            |::|||.|....||:.|.|||:.:|..|.:.     |.|..|..|......|.:|:|:|.|||..
Mouse   116 CKACGVHFASTTRKQTCLDCKKNFCMTCSSQEGNGPRLCLLCLRFRATAFQREELMKMKVKDLRD 180

  Fly    63 YLQSKHISTEGCLEKEELVGLVLTH---VAQVDRSRGSNASSNSPGRGQANPIDSLKQSCQNFFS 124
            ||....||||.|.||||||.|||..   :::.||:|       .|...||.|
Mouse   181 YLSLHDISTEMCREKEELVFLVLGQQPVISEADRTR-------VPHLPQAFP------------- 225

  Fly   125 NLSDNISDSLASFDSKVTTKPPESRQPEVPTHIFEQPRVSTREIPTYASAVNGGPQHVHVQQQAT 189
                                                                        :|||.
Mouse   226 ------------------------------------------------------------EQQAF 230

  Fly   190 TTNGGSQSSSSPSTSTQSSNNRDASSSSQAHVAHQEARNEEQEDAQSKSDCECSDEEIMATFSER 254
            .|.  .|:|:.|.||
Mouse   231 LTQ--PQTSTVPPTS-------------------------------------------------- 243

  Fly   255 VSISLKTDTSGRRVNAAAEPSPVDLANVDNGPAGNTAPSPGCSKPGSSSSKADASSQSSFEELGA 319
                                                        ||..||.|..:|
Mouse   244 --------------------------------------------PGLPSSPAQVTS--------- 255

  Fly   320 IGGISDESKANTDTNSSHLDQWQVLEVNRIEAVEETPTTSAADEILEVTLRSRPAVEGDDSEMGE 384
                                                 ...|.|:                    |
Mouse   256 -------------------------------------VPLAQDQ--------------------E 263

  Fly   385 STQALNVNQRPANPSPAFYPAVPQRTKKVTRRRSDGYLNRRYHSSDDESPVAPGGPGLSLGLSTL 449
            :.||:                              |::     |.|.|.|:.|
Mouse   264 TQQAV------------------------------GHV-----SQDHEEPIFP------------ 281

  Fly   450 SEHPEHGLHPHSHRQSCQRCGKNKTNIRRHVEKMRRHLENSQMSEEDIKRELQEFLTYLEQRTKS 514
                          :|..|                                     ...|..|:|
Mouse   282 --------------ESTAR-------------------------------------VPTEDETQS 295

  Fly   515 VDASDADSHAVSPLSVDAISVAAGGRSPDMPITPTIEFSPTQDEDIRWDDDEGIHVYAAPSDFEP 579
            ||:.|:                                                        |.|
Mouse   296 VDSEDS--------------------------------------------------------FVP 304

  Fly   580 TAGIDSRFVNLEDFEDLKDLEGLTVKQLKEVLMLHRVDYKGCCEKQELLDRVSRLWKTMRECP-- 642
                 .|..:|.|...|:|:|||||:||||:|..:.|:|||||||.||::||:||:|..:...
Mouse   305 -----GRRASLSDLTHLEDIEGLTVRQLKEILARNFVNYKGCCEKWELMERVTRLYKDQKGLQHL 364

  Fly   643 ----------AVEKLATDELCKICMDAPIECVFLECGHMATCTSCGKVLNECPICRQYIVRVVRF 697
                      ||.....:.|||||||:||:||.||||||.|||.|||.:|||||||||::|.|..
Mouse   365 VSGNEDQNGGAVPSGLEENLCKICMDSPIDCVLLECGHMVTCTKCGKRMNECPICRQYVIRAVHV 429

  Fly   698 FRA 700
            ||:
Mouse   430 FRS 432

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17019	NP_610827.2	FYVE_CARP	1..42	CDD:277289	16/43 (37%)
		RING-HC_CARP	651..698	CDD:438163	34/46 (74%)
Rffl	XP_006534053.2	FYVE_CARP2	113..161	CDD:277309	16/44 (36%)
		RING-HC_CARP2	381..430	CDD:438367	34/48 (71%)