DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17019 and APD4

DIOPT Version :9

Sequence 1:	NP_001286365.1	Gene:	CG17019 / 36425	FlyBaseID:	FBgn0033783	Length:	700	Species:	Drosophila melanogaster
Sequence 2:	NP_001118468.1	Gene:	APD4 / 6240532	AraportID:	AT2G38195	Length:	399	Species:	Arabidopsis thaliana

Alignment Length:	388	Identity:	90/388 - (23%)
Similarity:	141/388 - (36%)	Gaps:	89/388 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   350 EAVEETPTTSAADEILEVTLRSRPAVEGDDSEMGESTQALNVNQRPANPSPAFYPAVPQRTKKVT 414
            |.|...|.:|...:...:.::|..|.|.|.|:.|......|   ..:.||..|......|...|:
plant    64 ETVWLGPNSSILVKPSSIFVKSINAKELDFSKPGLQLYGFN---GQSTPSGYFVNWTESRVLSVS 125

  Fly   415 RRRSDG---YLNRRYHSSDDESPVAPGGPGLSLGLSTLSEHPEHGLHPHSHRQSCQRCGKNKT-- 474
            :....|   ||||..|.:...: :.|.|..:.|.::       .|: |..:|.|.:......|
plant   126 QNSYKGWPYYLNRGTHMNISYN-ILPKGSAVRLVIT-------EGM-PFFYRSSLKDIAFRDTAW 181

  Fly   475 --NIRRHVEKMRRHLENSQMSEEDIKRELQEFLTYLEQRTKSVDAS-DADSHAV----------S 526
              |:          ::.|.|.:.||.:....:||....:.|.|:.. |.|...|          .
plant   182 SWNL----------IQGSGMIQLDISKSKGYYLTVANLKRKDVEVELDIDVKVVLYDTKQSSYNC 236

  Fly   527 PLSVDAISVAAGGRSPDMPITPTIE-----FSPTQDEDIRWDDDEGIHVYAAPSDFEPTAGIDSR 586
            ..|....|.....|||       :|     .||...:.:..||:..|.:     .::|      |
plant   237 SFSNGECSFKMNERSP-------VENYAVVTSPALGQGVSIDDEWYIEL-----SYQP------R 283

  Fly   587 FVNLEDFEDLKDLEGLTVKQLKEVLMLHRVDYKGCCEKQELLDRVSRLWKTMRECPAVEKLATD- 650
            .:....|      .|:.:..:  ::.:|..:...||..:..|....    ::|.|...:|...|
plant   284 LIAYGSF------TGVLLSFM--LVAIHFCNKLKCCGGEGFLSEDD----SVRTCLLADKGDNDC 336

  Fly   651 ---------ELCKICMDAPIECVFLECGHMATCTSCG----KVLNECPICRQYIVRVVRFFRA 700
                     .||.||.|||.:|.||.|||..:|..||    :....|||||:.|:.|.|.:.|
plant   337 CNDVEASNKSLCAICFDAPRDCCFLPCGHCVSCYQCGTKIKRTKGRCPICRKKIMHVKRIYTA 399

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17019	NP_001286365.1	FYVE_CARP	1..42	CDD:277289
CG17019	NP_001286365.1	zf-C3HC4_3	650..694	CDD:290631	23/57 (40%)
APD4	NP_001118468.1	DUF4792	98..162	CDD:374322	15/74 (20%)
		DUF4793	191..301	CDD:374323	25/135 (19%)
		zf-C3HC4_3	344..390	CDD:372816	21/45 (47%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	53	1.000	Domainoid score	I4202
eggNOG	1	0.900	-	-		E1_KOG4275
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1361306at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3123
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.820