Protein Alignment CG17019 and Rffl

DIOPT Version :10

• Sequence 1: NP_610827.2
• Gene: CG17019 / 36425
• FlyBaseID: FBgn0033783
• Length: 700
• Species: Drosophila melanogaster
• Sequence 2: XP_006247031.1
• Gene: Rffl / 282844
• RGDID: 727916
• Length: 398
• Species: Rattus norvegicus
• Alignment Length: 719
• Identity: 152/719 - (21%)
• Similarity: 202/719 - (28%)
• Gaps: 423/719 - (58%)

  Fly     3 CESCGVEF-TVFRRKRACFDCKRYYCANCIAS-----RRCKRCSVFAQRPLSRTDLLKLKPKDLI 61
            |::|||.| :..|:::.|.|||:.:|..|.:.     |.|..|..|......|.:|:|:|.|||.
  Rat    82 CKACGVHFASTTRKQQTCLDCKKNFCMTCSSQEGNGPRLCLLCLRFRATAFQREELMKMKVKDLR 146

  Fly    62 FYLQSKHISTEGCLEKEELVGLVLTH---VAQVDRSRGSNASSNSPGRGQANPIDSLKQSCQNFF 123
            .||....||||.|.||||||.|||..   :::.||:|       :|...||.|
  Rat   147 DYLSLHDISTEMCREKEELVFLVLGQQPVISEADRTR-------APTLPQAFP------------ 192

  Fly   124 SNLSDNISDSLASFDSKVTTKPPESRQPEVPTHIFEQPRVSTREIPTYASAVNGGPQHVHVQQQA 188
                                                                         :|||
  Rat   193 -------------------------------------------------------------EQQA 196

  Fly   189 TTTNGGSQSSSSPSTSTQSSNNRDASSSSQAHVAHQEARNEEQEDAQSKSDCECSDEEIMATFSE 253
            ..|.  .|||:.|.||
  Rat   197 FLTQ--PQSSTVPPTS------------------------------------------------- 210

  Fly   254 RVSISLKTDTSGRRVNAAAEPSPVDLANVDNGPAGNTAPSPGCSKPGSSSSKADASSQSSFEELG 318
                                                         ||..||.|..:|
  Rat   211 ---------------------------------------------PGLPSSPAQVTS-------- 222

  Fly   319 AIGGISDESKANTDTNSSHLDQWQVLEVNRIEAVEETPTTSAADEILEVTLRSRPAVEGDDSEMG 383
                                    ||               |.|:
  Rat   223 ------------------------VL---------------AQDQ-------------------- 228

  Fly   384 ESTQALNVNQRPANPSPAFYPAVPQRTKKVTRRRSDGYLNRRYHSSDDESPVAPGGPGLSLGLST 448
            |:.||:                              |::     |.|.|.|:.         |.:
  Rat   229 ETQQAI------------------------------GHV-----SQDHEEPIF---------LES 249

  Fly   449 LSEHPEHGLHPHSHRQSCQRCGKNKTNIRRHVEKMRRHLENSQMSEEDIKRELQEFLTYLEQRTK 513
            .:..|.                                                      |..|:
  Rat   250 TARVPP------------------------------------------------------EDETQ 260

  Fly   514 SVDASDADSHAVSPLSVDAISVAAGGRSPDMPITPTIEFSPTQDEDIRWDDDEGIHVYAAPSDFE 578
            |||:.|:                                                        |.
  Rat   261 SVDSEDS--------------------------------------------------------FV 269

  Fly   579 PTAGIDSRFVNLEDFEDLKDLEGLTVKQLKEVLMLHRVDYKGCCEKQELLDRVSRLWKTMRECP- 642
            |     .|..:|.|...|:|:|||||:||||:|..:.|:|||||||.||::||:||:|..:...
  Rat   270 P-----GRRASLSDLTHLEDIEGLTVRQLKEILARNFVNYKGCCEKWELMERVTRLYKDQKGLQH 329

  Fly   643 -----------AVEKLATDELCKICMDAPIECVFLECGHMATCTSCGKVLNECPICRQYIVRVVR 696
                       ||.....:.|||||||:||:||.||||||.|||.|||.:|||||||||::|.|.
  Rat   330 LVSGNEDQNGGAVPSGLEENLCKICMDSPIDCVLLECGHMVTCTKCGKRMNECPICRQYVIRAVH 394

  Fly   697 FFRA 700
            .||:
  Rat   395 VFRS 398

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17019	NP_610827.2	FYVE_CARP	1..42	CDD:277289	15/44 (34%)
		RING-HC_CARP	651..698	CDD:438163	34/46 (74%)
Rffl	XP_006247031.1	FYVE_like_SF	79..128	CDD:333710	15/45 (33%)
		RING-HC_CARP2	347..396	CDD:438367	34/48 (71%)