Protein Alignment sug and Glis3

DIOPT Version :10

• Sequence 1: NP_610826.1
• Gene: sug / 36424
• FlyBaseID: FBgn0033782
• Length: 384
• Species: Drosophila melanogaster
• Sequence 2: NP_780668.3
• Gene: Glis3 / 226075
• MGIID: 2444289
• Length: 935
• Species: Mus musculus
• Alignment Length: 299
• Identity: 110/299 - (36%)
• Similarity: 139/299 - (46%)
• Gaps: 87/299 - (29%)

  Fly    21 PPLGYFTPYNTPPYIAAYSDSGSWLADHHQHHQQQHQQHQQQMQHIRFPTPPITPPRPIAGYGYR 85
            ||.|...||:..|               |.||                  |.:.|
Mouse   454 PPQGPPPPYHAHP---------------HLHH------------------PELLP---------- 475

  Fly    86 QRTQSVIMKARGQQDELCRSPVEFPDDSKSCSSSSECGTASDFVCNWTDCDRVFDTLDALAQHVT 150
             .|||:.:...|.::          |.....|....|       |.|.||..::|..:.|.:|:.
Mouse   476 -HTQSLSLAQTGLEE----------DGEMEDSGGKHC-------CRWIDCSALYDQQEELVRHIE 522

  Fly   151 QRHAIASLTDGLYYCRWRGCQRSERGFNARYKMLVHTRTHTKEKPHRCHL--CEKSFSRAENLKI 213
            :.| |.......:.|.|.||.|..:.||||||:|:|.|.|:.|||::|..  |:|:|||.|||||
Mouse   523 KVH-IDQRKGEDFTCFWTGCPRRYKPFNARYKLLIHMRVHSGEKPNKCTFEGCKKAFSRLENLKI 586

  Fly   214 HIRSHSGEKPYKCSFEGCQKAYSNSSDRFKHTRTHSMEKPYMCKVAGCQKRYTDPSSLRKHVKTF 278
            |:|||:|||||.|...|||||:||||||.||.|||...|||.|::.||.||||||||||||||.
Mouse   587 HLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTKPYACQIPGCTKRYTDPSSLRKHVKA- 650

  Fly   279 KHS---------------IH------LIASQPLTLPSVP 296
             ||               :|      .:|.|||...:.|
Mouse   651 -HSSREQQARKKLRSSTELHPDLLTDCLAVQPLQPATSP 688

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
sug	NP_610826.1	C2H2 Zn finger	170..190	CDD:275368	11/19 (58%)
		COG5048	192..>271	CDD:227381	53/80 (66%)
		C2H2 Zn finger	198..218	CDD:275368	13/21 (62%)
		C2H2 Zn finger	226..248	CDD:275368	15/21 (71%)
		C2H2 Zn finger	256..277	CDD:275368	16/20 (80%)
Glis3	NP_780668.3	C2H2 Zn finger	506..525	CDD:275368	5/18 (28%)
		C2H2 Zn finger	536..561	CDD:275368	14/24 (58%)
		SFP1	<558..652	CDD:227516	62/95 (65%)
		C2H2 Zn finger	569..591	CDD:275368	13/21 (62%)
		C2H2 Zn finger	599..621	CDD:275368	15/21 (71%)
		PHA03247	<612..861	CDD:223021	36/79 (46%)
		C2H2 Zn finger	629..651	CDD:275368	17/23 (74%)