Protein Alignment GLS and glsl

DIOPT Version :10

• Sequence 1: NP_001163129.1
• Gene: GLS / 36396
• FlyBaseID: FBgn0261625
• Length: 775
• Species: Drosophila melanogaster
• Sequence 2: XP_009296259.2
• Gene: glsl / 797748
• ZFINID: ZDB-GENE-131127-106
• Length: 643
• Species: Danio rerio
• Alignment Length: 566
• Identity: 195/566 - (34%)
• Similarity: 309/566 - (54%)
• Gaps: 39/566 - (6%)

  Fly    84 SFYDTSSTPKTKEDNAKLHREQ---------------EQRNAEDVLFDMFASEETGLISMGKFLA 133
            ||.....|.:|..::.|||..|               :::.|.|||||.|||  .|.::..:|..
Zfish    96 SFISNGGTKRTVPEHEKLHAGQAWQHLGRPDTHQGHFKKKVAADVLFDSFAS--GGRVNCNQFFE 158

  Fly   134 GLKTTGIRRNDPRVRELMDNLKKVHKLNNYETGSSAETQHLNRETFKAVVAPNIVLIAKAFRQQF 198
            .|.::||.|.|||:::....::|:.:.:.          .::|..|...|...:..|.||.:.:|
Zfish   159 ALWSSGIIRTDPRIKDCYSLMRKLQEADG----------TVDRSMFHRCVTGFVSFILKALQGRF 213

  Fly   199 VIPDFTSFVKDIEDIYNRCKTNTLGKLADYIPQLARYNPDSWGLSICTIDGQRFSIGDVDVPFTL 263
            |||||::|.::.:.::.:||..:..|..:.:..    :...||:|:||:||||.|:||...|.||
Zfish   214 VIPDFSTFAEETQKLFIKCKQLSSVKEKEDVGD----SGTKWGISVCTVDGQRLSLGDWAEPCTL 274

  Fly   264 QSCSKPLTYAIALEKLGPKVVHSYVGQEPSGRNFNELVLDQNKKPHNPMINAGAILTCSLMNALV 328
            ...|.||.|.:|:::.|...||.|||.|...:..:...|.:...||:|::..|||:..||:....
Zfish   275 GEISWPLIYGLAVDQQGSDYVHRYVGMEEYSKYESLFTLTKQGVPHSPLVETGAIICTSLLQLAT 339

  Fly   329 KPDMTSAEIFDYTMSWFKRLSGGEYIGFNNAVFLSEREAADRNYALGFYMRENKCFPKRTNLKEV 393
            :|.....|.::..::..:||...|::..|...:...|:...|.:||.||::|.||||:...:...
Zfish   340 RPVTDEEEKYESVLNIIRRLCNKEHVNLNCTSYQDLRKDIVRLHALSFYLQEKKCFPEGVGINAT 404

  Fly   394 MDFYFQCCSMETNCEAMSVIAASLANGGICPTTEEKVFRPEVIRDVLSIMHSCGTYDYSGQFAFK 458
            :|...||.|.|..||:.:.:||:|||||:||.:.::|..|..:|..|::|...|..|||..|.|:
Zfish   405 LDLLLQCLSTEVTCESGAALAATLANGGLCPLSGDQVMSPHAVRSTLTMMQVAGMNDYSRAFHFR 469

  Fly   459 VGLPAKSGVSGGMMLVIPNVMGIFAWSPPLDHLGNTVRGLQFCEELVSMFNFHRYDNLKHLSNKK 523
            |.:||||..||.:::|:|.|:|:..|||.||..||:.|.:.|||||||.|..|.:|.........
Zfish   470 VSVPAKSSQSGVVLMVVPAVLGLMCWSPGLDCNGNSWRSVHFCEELVSTFQLHSFDIRTPFRQVL 534

  Fly   524 DPRKHRYETKGLSIVNLLFSAASGDVTALRRHRLSGMDITLADYDGRTALHLAASEGHLECVKFL 588
            ..|:.:.|::|..|:|:|.:|..||:.:|||:.|.|.|:...|||||:|||:|||||.|:.::||
Zfish   535 CYRQWKVESEGYQIMNVLLAAYRGDLVSLRRYLLLGADVNAVDYDGRSALHVAASEGRLDVIRFL 599

  Fly   589 LE----QCHVPHNPKDRWGNLPVDEAENFGHCHVVEFLRSWAEKAD 630
            :|    .||:    |||||...:.||........::||:...:..:
Zfish   600 VENAGANCHL----KDRWGKTALQEAMRCNQDPAIQFLKKHTDNEE 641

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GLS	NP_001163129.1	EF-hand_14	110..201	CDD:465587	27/90 (30%)
		Glutaminase	223..511	CDD:461499	108/287 (38%)
		Ank_2	540..622	CDD:463710	36/85 (42%)
		ANK repeat	540..566	CDD:293786	10/25 (40%)
		ANK repeat	568..600	CDD:293786	17/35 (49%)
glsl	XP_009296259.2	None