|
Fly 189 PASAQTVSSSSQTGTIRQRTISGTQTVATAVGN-------LATI--SQQQPVQQSPLGKAQTPPS 244
|...:.||.:.|:.|..|.:::....|:....: :|.: |...|....|.| ..
Mouse 38 PPVYEAVSETMQSATGIQYSVAPNYQVSAVPQSSGSHGPAIAAVHSSHHHPTAVQPHG-----GQ 97
Fly 245 SVVANSIPVGGTTPPQGQSGNATPRLKVEDALSYLDQVKYQYADQPQIYNNFLDIMKEFKSHCID 309
.|.:::.|.....|.||| ....|||||||||||||||.|:..|||:||:||||||||||..||
Mouse 98 VVQSHAHPAPPVAPVQGQ--QQFQRLKVEDALSYLDQVKLQFGSQPQVYNDFLDIMKEFKSQSID 160
Fly 310 TPGVIERVSTLFKGHTELIYGFNMFLPPGYKIEIHSDALGCSVPVVSMPSPPGAPTSTGTVHMLT 374
|||||.|||.|||||.:||.|||.|||||||||:.:: .:|::.:| |.||.:.
Mouse 161 TPGVISRVSQLFKGHPDLIMGFNTFLPPGYKIEVQTN------DMVNVTTP-------GQVHQIP 212
Fly 375 GNSSMSGAGHIAIKTTNAATLTPAAGAGAAAAAAAVAQIQSAGAVNLMTHGGASLTQTTIHALQQ 439
||| :|.
Mouse 213 ------------------------------------------------THG-----------IQP 218
Fly 440 ATPPQSQSPGGGHVHVSVTNSTAANAVVPGQPGISVSAHNVPQNYSRDRERATITPTGQVAGAAA 504
...|..|.| :..::.:|..|.||....:|..| |:..:....||..|..
Mouse 219 QPQPPPQHP---------SQPSSQSAPTPAQPAPQPTAAKV----SKPSQLQAHTPASQQT---- 266
Fly 505 NVNASASIVVGGPPTPNSLSELSPHGGAGGGPGAGAAQHNLHHIQQAHQ--SILLGETG--QQNQ 565
||.|...|..||. .|.|. :|.||... |.||
Mouse 267 ------------PPLPPYASPRSPP-------------------VQPHTPVTISLGTAPSLQNNQ 300
Fly 566 PVEFNHAITYVNKIKNRFQNQPAKYKKFLEILHDYQREQKVMKEGSLNQGKMLTEQEVYTQVAKL 630
||||||||.||||||||||.||..||.||||||.||:||:..||...|....|||||||.|||:|
Mouse 301 PVEFNHAINYVNKIKNRFQGQPDIYKAFLEILHTYQKEQRNAKEAGGNYTPALTEQEVYAQVARL 365
Fly 631 FGQDEDLLREFGQFLPDATNHQSGQYMSKSA-----SVHNDHGKRPTATLSGGAHITMSSASPAP 690
|...||||.||||||||| .|...:||:. ||.||||
Mouse 366 FKNQEDLLSEFGQFLPDA---NSSVLLSKTTAEKVDSVRNDHG---------------------- 405
Fly 691 SGSPLHLGATTLPQIDKSAHAAAIGNLSAVNTSVSIKTYNNNQQQQNHVIGSGLNATRNDILFEK 755
|....||: ||:.|:
Mouse 406 -------GTVKKPQL-------------------------NNKPQR------------------- 419
Fly 756 DYHAGLQQQAHQRGAGVGGHHHLAGTAAGANIGRPGVGASVMVSYDKEHRNNHHVQKYVGHAPNQ 820
|:|
Mouse 420 --------------------------------------------------------------PSQ 422
Fly 821 NLTHGHNAKKSPSYGIPSVIGSMPHISDNSLDRSSPGISYATPPLPSGPHGQHNSGSATRRPGDD 885
| |...||
Mouse 423 N------------------------------------------------------GCQIRR---- 429
Fly 886 SLVGHYASGAPPAKRPKP---YCRDVSFSEASSKCTISDAAFFDKVRKALRSPEVYDNFLRCLTL 947
|..:||.|..:.|| ..::.|.::||.....:::.|||||||||||.|.|:||||||.:
Mouse 430 ----HSGTGATPPVKKKPKLMSLKESSMADASKHGVGTESLFFDKVRKALRSAEAYENFLRCLVI 490
Fly 948 FNQEIVSKTELLGLVSPFLMKFPDLLRWFTDFLGPPSGQPAGGLIDGMPLAATQRQGGGSSNSSH 1012
||||::|:.||:.||||||.|||:|..||.:|| |...|.|
Mouse 491 FNQEVISRAELVQLVSPFLGKFPELFNWFKNFL-------------------------GYKESVH 530
Fly 1013 DRGTSHQSAAEYV-QDVDLSSCKRLGASYCALPQSTVPKKCSGRTALCREVLNDKWVSFPTWASE 1076
......:.|.|.: .::|.:||||||:||.|||:|....||:|||.||:|||||.|||||:| ||
Mouse 531 LESFPKERATEGIAMEIDYASCKRLGSSYRALPKSYQQPKCTGRTPLCKEVLNDTWVSFPSW-SE 594
Fly 1077 DSTFVTSRKTQFEETIYRNIHRTEDERFELDLVIEVNSATIRVLENLQKKMSRMSTEELSKFHLD 1141
|||||:|:|||:||.|| |.||||||||:|:|.|.|||||||.:|||:||:|.||.:||.||
Mouse 595 DSTFVSSKKTQYEEHIY----RCEDERFELDVVLETNLATIRVLEAIQKKLSRLSAEEQAKFRLD 655
Fly 1142 DHLGGTSQTIHQRAIHRIYGDKSGEIITGMKKNPFVAVPIVLKRLKVKEEEWREAQKTFNKQWRE 1206
:.|||||:.||::|:.|||.||:.:||.|::|||.:||||||||||:|||||||||:.|||.|||
Mouse 656 NTLGGTSEVIHRKALQRIYADKAADIIDGLRKNPSIAVPIVLKRLKMKEEEWREAQRGFNKVWRE 720
Fly 1207 QNEKYYLKSLDHQAINFKPNDMKALRSKSLFNEIETLYDERHDQ--EDDAMEPFGPHLVLPYKDK 1269
|||||||||||||.||||.||.|.||||||.||||::||||.:| |::|..|.||||.|.|:||
Mouse 721 QNEKYYLKSLDHQGINFKQNDTKVLRSKSLLNEIESIYDERQEQATEENAGVPVGPHLSLAYEDK 785
Fly 1270 TILDDAANLLIHHVKRQTGIQKQEKQKIKQIIRQFVPDLFFAPRQPLSDDERDDAFPFLVDDNTK 1334
.||:|||.|:||||||||||||::|.|||||:..|:|||.||.|..|||.|.::
Mouse 786 QILEDAAALIIHHVKRQTGIQKEDKYKIKQIMHHFIPDLLFAQRGDLSDVEEEE----------- 839
Fly 1335 MDVDSPLGRTESSTRNAKSTPSESASPARSNASTSSVTPAGIKKETDDSKATTGSFAPASSATAS 1399
::|.|
Mouse 840 ------------------------------------------EEEMD------------------ 844
Fly 1400 SATPVDDATPSTSSAAAAASAASSSTVSGTEGKPKDDPLSSHKEEGAGSTSSGVATSPRQAQDTA 1464
||:|| |.|| .|...|.....|.:..|...||...
Mouse 845 ----VDEAT----------------------GAPK-----KHNGVGGSPPKSKLLFSNTAAQKLR 878
Fly 1465 GAGVDVEIKLEHPADFSNPKLLPPHAHGQREDESYTLFFANNNWYLFLRLHAILCDRLHVMYERA 1529
|. ||.|.||:.|||||:|:|||.|||.||..:..:|
Mouse 879 GM-----------------------------DEVYNLFYVNNNWYIFMRLHQILCLRLLRICSQA 914
Fly 1530 RLLAIEEERCRVNRRE----------STATALRLKPKPEIQVEDYYPTFLDMLKNVLDGNMDSNT 1584
.....||.|.|...|| |.|..||||...::.||||||.||||::::||||:||:.
Mouse 915 ERQIEEENREREWEREVLGIKRDKSDSPAIQLRLKEPMDVDVEDYYPAFLDMVRSLLDGNIDSSQ 979
Fly 1585 FEDTMREMFGIYAYISFTLDKVVSNAVRQLQYCVTERAALDCVELFATEQRRGCTGGFCRDAHKT 1649
:||::||||.|:|||:||:||::.:.|||||:.|::...:...:|:..|...|.|||........
Mouse 980 YEDSLREMFTIHAYIAFTMDKLIQSIVRQLQHIVSDEVCVQVTDLYLAENNNGATGGQLNSQTSR 1044
Fly 1650 FDREMSYQRKAESILNEENCFKVYIYKIDCRV--TIELLDSEPEEVDKPAALKA-QKFSKYVERL 1711
...|.:||||||.::::|||||:...:...:| |:||||:|.|..|.|...:. .::|.||||.
Mouse 1045 SLLESAYQRKAEQLMSDENCFKLMFIQSQGQVQLTVELLDTEEENSDDPVEAEVWTRWSDYVERY 1109
Fly 1712 ANPALGGGGNTGRSDSALGNDSVVDGSDIKTEADEDTAELRYREGGIGGAGKARFLVRNKRRSKL 1776
.: :|..:.|||... |.|..||.||.||
Mouse 1110 MS------------------------------SDTTSPELREHL-----AQKPVFLPRNLRR--- 1136
Fly 1777 LEEQVRQLFEHRRNRIEQHGTAASLEPISVDSAISSNSTTGGGGSGTNNNNNNNNNNNSWGGKRL 1841
:|:. :|.|.:|. ..|...|:.....| :
Mouse 1137 ----IRKC---QRGREQQE------------------------KEGKEGNSKKTMEN-------V 1163
Fly 1842 ERLGAPQVGLAEQYAFNDRDEISTNISNGR-CFVTSKNLKLLKYDAVRRAKKSHCRVTQAKYAHF 1905
|.| |:.|....:::.: .:|......:.:..|:.||.:||.||::..:..|
Mouse 1164 ESL--------------DKLECRFKLNSYKMVYVIKSEDYMYRRTALLRAHQSHERVSKRLHQRF 1214
Fly 1906 QTYVNKWLQQHVSEQQQQNCVDWLLGKTADQINASGWGSASKTKTVQQKDTSKTPYRIYNRYRVV 1970
|.:|:||.::||..:.......||:|:..: |....|.|. ||....:...|:|||.
Mouse 1215 QAWVDKWTKEHVPREMAAETSKWLMGEGLE-------GLVPCTTTC---DTETLHFVSINKYRVK 1269
Fly 1971 QSAV 1974
...|
Mouse 1270 YGTV 1273
| 
