DRSC/TRiP Functional Genomics Resources

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Protein Alignment DUBAI and USP17L22

DIOPT Version :10

Sequence 1:NP_610784.1 Gene:DUBAI / 36361 FlyBaseID:FBgn0033738 Length:852 Species:Drosophila melanogaster
Sequence 2:NP_001243792.1 Gene:USP17L22 / 100287513 HGNCID:44450 Length:530 Species:Homo sapiens


Alignment Length:412 Identity:113/412 - (27%)
Similarity:166/412 - (40%) Gaps:108/412 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly   338 VALAKAMHENAQPWGRRNARV--GLVNLGNTCYMNSVLQALAMTSDFSRQILLIE----CN---S 393
            ||...|..|......||.|.|  ||.|:|||||:|:.||.|..|...:..:|..|    |:   .
Human    58 VARQLAPREKLPLSSRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRHKG 122

  Fly   394 VLLMKVQQQIALMHHSLRYELTPSRVLNATRPPSFTPGLQQDSSEFLGYLLDLLHEHEINSSSVT 458
            .:|..:|..|....|:..:.:.||:.|.|    .|..|.|:|:.|||.:.:|.:     ..:.:.
Human   123 CMLCTMQAHITRALHNPGHVIQPSQALAA----GFHRGKQEDAHEFLMFTVDAM-----KKACLP 178

  Fly   459 GHSVGPPKTGREVDDVPALLSEDILSSGVIPYNSKDHELSSGSNSDNCNHKPTPTPPATPTKATN 523
            ||        ::||                 ::|||..|                          
Human   179 GH--------KQVD-----------------HHSKDTTL-------------------------- 192

  Fly   524 GLKQQGQQVDQAKPPSTIDKTFAGKLSTTYRCLNCGWESRNEDSFRELQLSFPDDKEDCGATNYS 588
                             |.:.|.|...:..:||:|...|...|.:.::.|       |..|.. |
Human   193 -----------------IHQIFGGYWRSQIKCLHCHGISDTFDPYLDIAL-------DIQAAQ-S 232

  Fly   589 VQDLIEYYCSPEKLDGDNQYFCPQCKKLCDAERHIGVTQAPKNLILTLKQFKYDQKYHFRTKLMH 653
            ||..:|....||:|:|:|.|.|..|.:...|.:.:.:..:.|.|||.||:|. |..   ..|:..
Human   233 VQQALEQLVKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFS-DVT---GNKIAK 293

  Fly   654 KVFHDESVTVKMSAKDSLQEMSTVHYDLYAGVVHAGYSMDSGHYFTFAADQAKNWYKFNDNVVTH 718
            .|.:.|  .:.|....|.|....:.|.|||.:||||:|..:||||::...|...|||.:|..||.
Human   294 NVQYPE--CLDMQPYMSQQNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTA 356

  Fly   719 SKPEEMHNLTS--PNTPYILFY 738
            |      ::||  ....|:|||
Human   357 S------SITSVLSQQAYVLFY 372

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DUBAINP_610784.1 Peptidase_C19H 359..739 CDD:239129 105/389 (27%)
USP17L22NP_001243792.1 Peptidase_C19E 79..373 CDD:239126 105/391 (27%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 382..412
HABP4_PAI-RBP1 <417..454 CDD:461421
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 476..530
Blue background indicates that the domain is not in the aligned region.

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