DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment garz and FBXO8

DIOPT Version :9

Sequence 1:	NP_610761.2	Gene:	garz / 36337	FlyBaseID:	FBgn0264560	Length:	1983	Species:	Drosophila melanogaster
Sequence 2:	NP_036312.2	Gene:	FBXO8 / 26269	HGNCID:	13587	Length:	319	Species:	Homo sapiens

Alignment Length:	176	Identity:	47/176 - (26%)
Similarity:	82/176 - (46%)	Gaps:	20/176 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   647 LSQGTERFNQRPEKGIQYLQEHGILNAELDPMQVALFLRENPGLDKKMIGEYISKKKNV--DSKI 709
            |.:|:..||..|::|:.|....|||:.  .|.::|.|:.....|:.|.:..|:.::::|  |...
Human   139 LDEGSLTFNANPDEGVNYFMSKGILDD--SPKEIAKFIFCTRTLNWKKLRIYLDERRDVLDDLVT 201

  Fly   710 LINFVDSFDFTGLRVDQALRLYLETFRLPGE-APLIFLVLEHFSDHWHKQNQDPFANV----DAA 769
            |.||.:.|      :..|||.:......|.| ...:..::..||..:...|.|....:    ||.
Human   202 LHNFRNQF------LPNALREFFRHIHAPEERGEYLETLITKFSHRFCACNPDLMRELGLSPDAV 260

  Fly   770 FRLAYAIIMLNMDQHNSNAKRLNVPMTLEDFTKNLR--GLNGGEDF 813
            :.|.|::|:|::|..:.:.|.   .|:..:|.:|.|  ..|..|||
Human   261 YVLCYSLILLSIDLTSPHVKN---KMSKREFIRNTRRAAQNISEDF 303

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
garz	NP_610761.2	COG5307	346..>1062	CDD:227623	47/176 (27%)
		Sec7_N	370..512	CDD:289549
		Sec7	643..830	CDD:279680	47/176 (27%)
FBXO8	NP_036312.2	F-box-like	74..112	CDD:372399
FBXO8	NP_036312.2	Sec7	133..312	CDD:238100	47/176 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5307
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D815698at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820