Protein Alignment: garz and gbf1

• Sequence 1: NP_610761.2
• Gene: garz
• FlyBaseID: FBgn0264560
• Length: 1983
• Species: Drosophila melanogaster
• Sequence 2: XP_012822305.1
• Gene: gbf1
• XenbaseID: XB-GENE-1012128
• Length: 1857
• Species: Xenopus tropicalis
• Alignment Length: 1934
• Identity: 830/1935 (43%)
• Similarity: 1156/1935 (60%)
• Gaps: 215/1935 (11%)

  Fly     8 IYVVRGEMATLMTAMRRGTRWNATAYVDDENDSLLKLFIDLKHELNRIEDLRQIEPQVFLAPFLE 72
            ||:|:||::.::.|::|..||:....||:|.|.||..|..||..||.|::|.:|||.|||.||||
 Frog     6 IYIVQGEISIVVGAIKRNARWSMHTPVDEEQDPLLHSFSVLKEVLNNIKELSEIEPNVFLRPFLE 70

  Fly    73 VIRTADATGPLTSLALASVNKLLSYGLIDPTSPNLADIVERIADAVTHARFMGTDQSSDGVTFMR 137
            |||:.|.|||:|.|||.||||.|||.||||:....|:.:|.:|||||||||:|||.:||.|..|:
 Frog    71 VIRSEDTTGPITGLALTSVNKFLSYALIDPSHEGTAEGIENMADAVTHARFVGTDPASDEVVLMK 135

  Fly   138 VIEVLHTLIRSPEGAAVSNVSMCEVMLSCFKISFEPRLSELLRRSAEKSLKDMVLLFFMRLPQFA 202
            :::||.||:.:|.||.::|.|:||:|.|||:|.||.|||||||:|||.:|.|||.|.|.|||||.
 Frog   136 ILQVLRTLLLTPVGAHLTNESVCEIMQSCFRICFEMRLSELLRKSAEHTLVDMVQLLFSRLPQFK 200

  Fly   203 EERSD---TMLQKRFTIGDAASGATQEKLKRKTVAQAQTAPRKSSAVEEPPQTPQSANLTVPGHL 264
            ||...   |.::|........|.:::.|.::|:..|.:...:..:|.|...|.|.....|:..:|
 Frog   201 EEAKSYIGTNMKKLKMRAGGMSDSSKWKKQKKSPRQPRHVTKAMAAAEPSSQQPVVNGTTITTNL 265

  Fly   265 KAPILATTPASPAGN--ILDMQGKITQ---TPTT--------TASTGEDETTV-PETPVI----- 310
            ...:.....:||..|  |..:..:.|.   :|||        .|::.||.:.: |.:|.:
 Frog   266 TGEVPFIDASSPDANFPISGVSSEATSAVVSPTTDSGVDMSSQATSKEDLSELDPASPSLSAIQQ 330

  Fly   311 ---------------QVE----------STESEP-LLDGETGEA-TSTLAEANSSEYINSVGVRF 348
                           ::|          |.||.| :||.....| .|..|..:..:|:|..||||
 Frog   331 SGDICLSEQQNQDDDKIEDLMERHTYSASVESIPEVLDDNVSLADQSDSASVHDMDYVNPRGVRF 395

  Fly   349 TQQSTDHDVTSLSPYGLPFIQELFRFLIILCNPLDKQNSDSMMHTGLSLLTVAFEVAADNIGKYE 413
            | ||:..:.|.|.|||||.|:|||||||.|.||.|:.||:.|:|.||.|:|||.|.|.  |..|.
 Frog   396 T-QSSQKEGTVLVPYGLPCIRELFRFLISLTNPHDRHNSEVMIHMGLQLITVALESAP--IENYV 457

  Fly   414 GLLELVKDDLCRNLISLLSSERLSIFAADLQLCFLLFESLRGHLKFQLEAYLRKLSEIIASDNPK 478
            .||.||||:|||:|..|||.|||:::||.|:.||||||.:|.|||||||.|::||.:||..:|||
 Frog   458 SLLGLVKDELCRHLFQLLSIERLNLYAASLRACFLLFEGMREHLKFQLEMYIKKLMDIITVENPK 522

  Fly   479 TPYEMRELALDNLLQLWRIPGFVTELYINYDCDLYCTDMFESLTNLLSKYTLSATNAVYSTHIIS 543
            .||||:|:||:.::||||||.||||||||||||.||:::||.||.||||.....:..:|:||::|
 Frog   523 MPYEMKEMALEAIVQLWRIPSFVTELYINYDCDYYCSNLFEDLTKLLSKNAFPVSGQLYTTHLLS 587

  Fly   544 MDTLLSVIDSIERNCAASKNSSNNRESLPEAAPATGGSRHSRHNSGLEGIVIDSGNSVAAEEK-- 606
            ::.||:||||.|.:|.| ||.||..:...|....:|.......:||       :.|..:.|.|
 Frog   588 LEALLTVIDSTESHCQA-KNLSNVSQDKKETGKPSGDLSEGTKDSG-------NLNEHSIEVKPF 644

  Fly   607 ---VENIASFINASSH------RLRLQ------SGGEGVGITS-----------EQLAKVKQKKR 645
               .||..|....|.|      .|.:|      .|||...:..           ::|..:|.||:
 Frog   645 TVSAENNGSKPPTSGHLMADKMTLGVQETEYSTDGGEKKTLKKPQRFSCLLPNVQELNDIKTKKK 709

  Fly   646 LLSQGTERFNQRPEKGIQYLQEHGILNAELDPMQVALFLRENPGLDKKMIGEYISKKKNVDSKIL 710
            ||..|||:|||:|:||:|:|||..:|...:|..:||.:|||||.||||||||::|.:||:|  :|
 Frog   710 LLITGTEQFNQKPKKGVQFLQEKDLLATPMDNAEVAQWLRENPRLDKKMIGEFVSDRKNLD--LL 772

  Fly   711 INFVDSFDFTGLRVDQALRLYLETFRLPGEAPLIFLVLEHFSDHWHKQNQDPFANVDAAFRLAYA 775
            .:||.:|.|.|||||:|||||||.||||||||:|..:||.|::||.|.|..|||:.||.|.||||
 Frog   773 ESFVGTFHFQGLRVDEALRLYLEAFRLPGEAPVIQRLLEAFTEHWRKSNGTPFAHSDACFALAYA 837

  Fly   776 IIMLNMDQHNSNAKRLNVPMTLEDFTKNLRGLNGGEDFDQEMLAQVFNAIKNEEIVMPAEQTGLV 840
            :||||.||||.|.::.|||||||:|.|||:|:|||:||||:||..:::||||||||||.||||||
 Frog   838 VIMLNTDQHNHNVRKQNVPMTLEEFRKNLKGVNGGKDFDQDMLEDIYHAIKNEEIVMPEEQTGLV 902

  Fly   841 RENYQWKVLLRRGDTHDGHFHYVHDASYDVEIFNIVWGASLSALSFMFDKS-TETGYQRTLAGFS 904
            :|||.|.|||.||.|.:|.|.:|...|||.::|.:.||.:::|||::|||| .||..|:.::||.
 Frog   903 KENYFWNVLLHRGATPEGMFLHVDPGSYDHDLFTMTWGPTIAALSYVFDKSMDETIIQKAISGFR 967

  Fly   905 KSAAISAHYNLHSDFDALVLTLCKFTTLLSSVEQHEPAPANNETQQAVNFGLNGKAQAAMRTVFL 969
            |.|.|||||.|...||.|:::|||||||.|...::.|..          ||.|.|||.|.:|||.
 Frog   968 KCAMISAHYGLSDVFDNLIISLCKFTTLSSEAVENLPTV----------FGSNLKAQIAAKTVFH 1022

  Fly   970 LVHDYGDCLRESWKHILDLYLQLFRLKLLPKSLIEVEDFCEANGKAMLILEK-PREKQESGLFSS 1033
            |.|.:||.|||.||:|:|..|||||.:||||:::|||||.:.|||..|..|: |..:.|    |:
 Frog  1023 LSHRHGDILREGWKNIMDSMLQLFRAELLPKAMVEVEDFVDPNGKISLQREEIPANRGE----ST 1083

  Fly  1034 LYSFIS--------SEGQREPTYEEQDFIKLGRKCIKECQLDQMLQESKFVQLESLQELLKCVLA 1090
            :.||:|        ....|.|:.|.|:..||..:|||.|..::::.||||:||||||||:|.:::
 Frog  1084 VLSFVSWLTLSGTEQSSLRGPSTENQEAKKLALECIKLCDPEKLITESKFLQLESLQELMKALIS 1148

  Fly  1091 LLKAPQGHKSIGLPYAEDQTVFWMEFLVKIVVHNRDRMIPLWPAVRDQMYLLLMGSASCGYDYLL 1155
            :....:       .|.|:...|.:|.|::||:.||||:..:|.||||.:|.|.:.:..  :.:|:
 Frog  1149 VTPDEE-------TYDEEDAAFCLEMLMRIVLENRDRVGCVWQAVRDHLYRLCVHAVE--FCFLV 1204

  Fly  1156 NRCIVAVLKLAIYLMRNEELCPIVLQSLKMLLMLKPALLLRISKQISIGIYELLKTSAQNIHSEQ 1220
            .|.:|.:|:|||.|:|.||:...|:.||::|||:||.:|.::|:|::.|::|||||:|.||||..
 Frog  1205 ERAVVGLLRLAIRLLRREEISGQVILSLRILLMMKPTVLSKVSRQVAFGVHELLKTNAANIHSSN 1269

  Fly  1221 DWQIIFNLLECVGAGAVPPNYDDAQLPLPPNGSAKSDGAISGEEDATAVPERGYTSDSEI----- 1280
            ||..:|.||||:|||..||...........:..|:||..:|....:....:||||||||:
 Frog  1270 DWYTLFCLLECIGAGVKPPPALQVTTRADNDTGAQSDSEVSSYHPSEVNLDRGYTSDSEVYAEHS 1334

  Fly  1281 TKASAAPAVSSPSAEN--WILVNNKDSELTTASRPQSPPSLSAPPVNTLVYNCQL-LDHAPF--- 1339
            .::....:|:.....|  |::|..:|.:.:..:...:.|..:| |||.  |:..: ||..|.
 Frog  1335 KQSKMHRSVTDVDMMNSGWLMVGKEDVDSSKVATVINKPVANA-PVNQ--YSLTIGLDFGPHDTK 1396

  Fly  1340 ALFKCWDSLAFIVRSVAHITPYNFEACVRCIRIFVEACRDGGI---RQRRKLES---AAKQKSSK 1398
            :|.|..:||:||||..||:||.|||.||:.||:||||..:||:   .|.:::::   .:|....|
 Frog  1397 SLMKSVESLSFIVRDAAHVTPENFELCVKTIRVFVEASLNGGVWYKSQEKRVKNHKYDSKSNRFK 1461

  Fly  1399 KRSERKPGMASSASSSNLTLLTGDPSDNQINGNAAEQED--LAQRYEQLSIQ----LLDLMYTLY 1457
            |:::.|........:||         ..|...::.::||  :...|..:|:|    |||||:||:
 Frog  1462 KKTKEKENSVRRTRASN---------QRQYRSHSDDEEDESVPASYHTVSLQVSHDLLDLMHTLH 1517

  Fly  1458 TRTAQIFRWWAEEGCTVPQSA--------ALWSPGWCPLLQGIARLAMDRRREVRTHAISCLQQR 1514
            ||.|.|:..||||...:..:|        .|||..|||||||||.|..|.||:||..|::.| ||
 Frog  1518 TRAATIYSSWAEEQRNLETAAEKITADSKTLWSNCWCPLLQGIAWLCCDARRQVRMQALTYL-QR 1581

  Fly  1515 ALLVHDLQTLSGTEWCSCFHQVLFPLLNELLPESNAAGQLDAALLEESRIRTATIMSKVFLQHLT 1579
            ||||||||.|...||.|||::||||||.:||...:.|   |...:||:|:|.:|::||||||||:
 Frog  1582 ALLVHDLQALDALEWESCFNKVLFPLLTKLLENISPA---DVGGMEETRMRGSTLLSKVFLQHLS 1643

  Fly  1580 TLIELGNAFNELWLDILDYIERFMKVG-SDTLSEQMQEILKNMLLVMHSVRVFHNQDGSLQQA-L 1642
            .|:.| :.|..|||.|||:::::|..| ||.|.|.:.|.||||||||.:..:||:.|.....: |
 Frog  1644 PLLSL-STFAALWLTILDFMDKYMHAGSSDLLPEAIPESLKNMLLVMDTAGIFHSADSRTGYSDL 1707

  Fly  1643 WELTWRRIGEFLPNLKEELF-----HDEGKRAQTLT----NPAPQAAVAAAPQQQLPAVTILPRQ 1698
            ||:||.||..|||.|:||||     .|......|.|    .|.||:..:..|.:|.|.      .
 Frog  1708 WEITWERIDCFLPRLREELFKQTVIQDPPNIVTTETPVEPRPPPQSTQSERPAEQGPC------D 1766

  Fly  1699 TQVSNELVVSAP---TPPAATPLLGSPVESPRRSIILQPPMADVLQQPPSFVFAQPIIVPPQPPA 1760
            ::..:..:.|||   :..:.||:..|||..      :.||:..           .|:|:.|....
 Frog  1767 SETQSLAISSAPVVGSSSSCTPVRVSPVTD------IPPPITQ-----------SPVILHPLTSP 1814

  Fly  1761 VTDPIPPSTLLPDLVNEATAAAVQATTTSPTHS-PQEAEQPASIVQQTN 1808
            :...:||.: ||.::|   .|.::||:..|..| |:.|:  .|.|.:.|
 Frog  1815 LQVGVPPMS-LPIILN---PALIEATSPVPLLSTPRPAD--VSSVSEVN 1857

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
garz	NP_610761.2	COG5307	346..>1062	CDD:227623	383/754 (51%)
		Sec7_N	370..512	CDD:289549	91/142 (64%)
		Sec7	643..830	CDD:279680	117/187 (63%)
gbf1	XP_012822305.1	COG5307	409..>1158	CDD:227623	390/782 (50%)
		Sec7_N	410..555	CDD:289549	94/147 (64%)
		Sec7	707..892	CDD:279680	117/187 (63%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930				C87698155
eggNOG	1	0.900				E1_COG5307
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000				H37897
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010
OrthoDB	1	1.010				D49474at33208
OrthoFinder	1	1.000				FOG0003012
OrthoInspector	0	0.000	Not matched by this tool.
Phylome	1	0.910		0.667	Consistency score
RoundUp	0	0.000	Not matched by this tool.
TreeFam	1	0.960
	8	7.720