Protein Alignment CG30046 and fat-spondin

DIOPT Version :10

• Sequence 1: NP_725129.1
• Gene: CG30046 / 36334
• FlyBaseID: FBgn0050046
• Length: 839
• Species: Drosophila melanogaster
• Sequence 2: NP_477435.1
• Gene: fat-spondin / 36919
• FlyBaseID: FBgn0026721
• Length: 763
• Species: Drosophila melanogaster
• Alignment Length: 859
• Identity: 252/859 - (29%)
• Similarity: 349/859 - (40%)
• Gaps: 227/859 - (26%)

  Fly     9 LVELLLLGSLVIGRVSSLICTRRPA--NTGSPKSPVDENFMISVSGNPETYILGQEYNVSLNAFN 71
            |:.|:::..|.|..|::  |.|.|.  |.|. ::..|..:.:.|:..|..|:.|:.||:.|....
  Fly     8 LIRLIVVIWLTISMVTA--CPRAPTHLNHGR-RTRGDNGYKLIVADGPNGYVPGKTYNLLLLGSR 69

  Fly    72 GH----RYISFIMALENENG----DFSYNDDLGRFEL-SDLIETRFSPNCINMVENTNTNSKTHM 127
            .|    .:..|.:..|...|    ..:....:|||:| ||.: |:|:..|:|.|...:...||.:
  Fly    70 THLKVQHFTHFTITAEAHTGARRPQAASPRRVGRFQLFSDSL-TQFNDRCVNTVSEADDLPKTEV 133

  Fly   128 HLTWVAPSEPGSGCVLIRATVQQHREVWHMDDGGLTKRICEEVTDDVESQPTAPAAVDVPCCACD 192
            .:.|||| |.|||||.:.|.|.:....|..|||.|:..|||...|        .||....|||||
  Fly   134 QVMWVAP-ESGSGCVSLSAMVYEGPRAWFADDGNLSTVICERKPD--------AAAAQKECCACD 189

  Fly   193 EARYELIFEGVWSRNLHPKDFPTRGWETRFCELLGAAHSSDYRFWESGELASVAMKEYAEHCSSR 257
            ||:|..:|||:||...||||:|...|.|.|.:::||:|.|::.||....:|:...:..||..|..
  Fly   190 EAKYSFVFEGIWSNETHPKDYPFAIWLTHFSDVIGASHESNFSFWGENHIATAGFRSLAEWGSPA 254

  Fly   258 LLEREFSINFRDQKIRTIIKARGPSYPNISSKTMASVRVDPIHHMVSFASKIEPSPDWIVGVTGL 322
            .||.|...|  ..|:||:|||.|..|||::..|.:..|||..|..||..|...|||||:||::||
  Fly   255 ALETELRAN--GPKLRTLIKAAGLWYPNVNQNTSSKFRVDRKHPKVSLVSMFGPSPDWVVGISGL 317

  Fly   323 ELCLRNCTWMEEKVINLYPWDVGTDSGPTYTSSDQPQVPPDVIRRMRSDFPNDPRSPFYDISGTP 387
            :||..:|:|.|....:|:|||.|||||.:|.|.:....||:.:.|:.:.:|.|||:|||:.....
  Fly   318 DLCTEDCSWKESMDFDLFPWDAGTDSGISYMSPNSETQPPERMYRITTMYPEDPRAPFYNPKSRE 382

  Fly   388 MKPMAILTVKRQRIYERRCADE----------DSNNDPDVPRECFTHPWSSWSDCSSKCGVGMQY 442
            |.|:|.|.::|::|..|.|.||          |...:.|...||....:|:||.||..||.|::.
  Fly   383 MTPLAKLYLRREKIVSRNCDDEFLQALQLEVSDDAEEQDTRAECRVGDYSAWSPCSVSCGKGIRM 447

  Fly   443 RRRVYKQPELARVYNC-------------------NEAQYEER---------------------- 466
            |.|.|..|..|....|                   ..||.::|
  Fly   448 RSRQYLYPAAADQNKCARQLVAKEMCVAAIPECADGPAQSKDRDDDEGENLANSQSLVGSNGEGA 512

  Fly   467 ------------ECQGEMCG--------------------------QNNLMREPEEFEDLE-PDP 492
                        ||... ||                          :|..||....:|.:| |||
  Fly   513 GLCKTSPWSVWSECSAS-CGIGITMRTRTFVNHLGRKRCPHITIVEKNKCMRPDCTYEQVELPDP 576

  Fly   493 RRIGYQPSQQRRAECELSSWGSWSPCSVTCGDGYEMRQRQYL---NPQAEFDCQGVHRMELQETR 554
                         :|..|.|..|||||.|||.|..:|.|..|   .|..| .|  ..||||.:.:
  Fly   577 -------------QCPTSQWSDWSPCSSTCGRGVTIRTRLLLLENGPDKE-SC--TQRMELHQQK 625

  Fly   555 KC-SGRDCLGSLPGSYSTDMDSPYGGASPGRIGGNMYGPQLEPEAENFGDYDDSRNGAVGGFEVG 618
            :| :..||..:...:....:.:|..|...|......|.||               |.....|..|
  Fly   626 ECVNPIDCHINAEQAKDICVQAPDPGPCRGTYMRYAYDPQ---------------NQHCYSFTYG 675

  Fly   619 NLKGNIGNW-----ALNRQTNLGRDVPSLRPTNYDRARQQAEKSERTTWSGQSRPDDPR---LED 675
            ..:||..|:     .||....|                       |:.:|  ||.|.||   |.|
  Fly   676 GCRGNRNNFLTENDCLNTCNVL-----------------------RSPYS--SRVDQPRACVLSD 715

  Fly   676 VERAPWHRQRP-----------SNKYGSIVEAPEMVSPREPWQRANNFGNPDMYTPGGDVDPSLS 729
                 |....|           |.:|  :|..|:            |.|.|            .|
  Fly   716 -----WSVWSPCSVSCGVGVSESRRY--VVTEPQ------------NGGQP------------CS 749

  Fly   730 YRCFQMVQTAQPRC 743
            .|..:....|.|.|
  Fly   750 KRLVKSRSCAMPAC 763

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30046	NP_725129.1	Reeler	28..167	CDD:260081	47/149 (32%)
		Spond_N	194..390	CDD:461924	83/195 (43%)
		TSP1	425..473	CDD:214559	19/100 (19%)
		TSP1_spondin	507..561	CDD:465948	23/57 (40%)
fat-spondin	NP_477435.1	Reeler	24..172	CDD:260081	47/152 (31%)
		Spond_N	191..385	CDD:461924	83/195 (43%)
		PTZ00441	<419..>497	CDD:240420	20/77 (26%)
		TSP1_spondin	426..>463	CDD:480609	14/36 (39%)
		TSP1_spondin	515..566	CDD:480609	7/51 (14%)
		TSP1_spondin	578..630	CDD:480609	23/54 (43%)
		Kunitz-type	644..695	CDD:444694	14/65 (22%)
		TSP1_spondin	711..763	CDD:465948	15/82 (18%)