Protein Alignment CG30046 and spon1

DIOPT Version :10

• Sequence 1: NP_725129.1
• Gene: CG30046 / 36334
• FlyBaseID: FBgn0050046
• Length: 839
• Species: Drosophila melanogaster
• Sequence 2: NP_001090741.1
• Gene: spon1 / 100036727
• XenbaseID: XB-GENE-991006
• Length: 803
• Species: Xenopus tropicalis
• Alignment Length: 796
• Identity: 218/796 - (27%)
• Similarity: 337/796 - (42%)
• Gaps: 190/796 - (23%)

  Fly    28 CTRRPANTGSPKSPVDENFMISVSGNPETYILGQEYNVSLNA-----FNGHRYISFIMALENENG 87
            |:|.....||.:......|.:.|.|:||.|..|..|.|:|.|     |.|...|:.....|.|..
 Frog    39 CSRILRAQGSTRKEGYNEFSLRVEGDPEFYKPGNTYRVTLLAASPAYFRGFTLIALKEGKEGEKE 103

  Fly    88 DFSYNDDLGRFELSDLIETRFSPNCINMVENTNTNSKTHMHLTWVAPSEP-GSGCVLIRATVQQH 151
            :    |..|.|::.|..:|:|..||...|..:....:|.:.:.|.||  | |||||:::|::.|.
 Frog   104 E----DHAGTFQIIDDEDTQFMSNCPVAVTESTPRRRTRIQVLWTAP--PIGSGCVILKASIVQK 162

  Fly   152 REVWHMDDGGLTKRICE-EVTDDVESQPTAPAAVDVPCCACDEARYELIFEGVWSRNLHPKDFPT 215
            :.::..|:|.||||:|| ::|.:..::...|     .||||..|:|.|.|.|.||...||||:|.
 Frog   163 KIIYFQDEGSLTKRMCEPDLTLEGGNEKPIP-----DCCACGTAKYRLTFYGNWSEKTHPKDYPR 222

  Fly   216 RG--WETRFCELLGAAHSSDYRFWESGELASVAMKEYAEHCSSRLLEREFSINFRDQKIRTIIKA 278
            |.  |..    ::|.:||.:|..||.|..||..:|:.||..|...:|.|  |..:..::.|:|||
 Frog   223 RANHWSA----IIGGSHSKEYVLWEYGGQASDGVKQVAELGSPVKMEEE--IRQKGDEVLTVIKA 281

  Fly   279 RG--PSYP--NISSKTMASVRVDPIHHMVSFASKIEPSPDWIVGVTGLELCLRNCTWMEEKVINL 339
            :.  |::.  |:.:...|...||...|::||.:.:.|||||.||::..:||.:.|.|:::.:.:|
 Frog   282 KAQWPAWQPLNVRAAPSAEFSVDRSRHLMSFLAMMGPSPDWNVGLSSEDLCTKECGWVQKVIQDL 346

  Fly   340 YPWDVGTDSGPTYTSSDQPQVPPDVIRRMRSDFPNDPRSPFYDISGTPMKPMAILTVK------- 397
            .|||.|||||.||.|.::|.:|.|.||.:.|  .:.|:|||||..|.|:.|:|.:.::
 Frog   347 IPWDAGTDSGVTYESPNKPSIPQDKIRPLTS--LDHPQSPFYDPEGGPIIPVARVVIERIARKGD 409

  Fly   398 ----------------------------------------------------RQRIYERR----- 405
                                                                |||:.:.:
 Frog   410 QCNIVPDNVDDIVPDLVTEEKEEDDTPETCIYSNWSPWSACSSATCDKGKRMRQRMLKAQLDLSV 474

  Fly   406 ---------------CADEDSNNDPDVPRECFTHPWSSWSDCSSKCGVGMQYRRRVYKQ-PELAR 454
                           |:|::::.       |....|.:||.||:.||:||:.|.|..|| ||...
 Frog   475 PCPDTQDFEPCMGPGCSDDEAST-------CMMSEWITWSPCSASCGMGMRSRERYVKQFPEDGS 532

  Fly   455 VYNCNEAQYEE----RECQGEMCGQNNLMREPEEFED--------LEPDPRRIGYQPSQQRRAE- 506
            :......:.|:    .||:...|    ::.|..|:|:        ::...|.|...|:.....:
 Frog   533 MCKVPTEETEKCIVNEECEPSSC----IVTEWAEWEECSATCGMGMKKRHRMIKMTPADGSMCKA 593

  Fly   507 -----------------CELSSWGSWSPCSVTCGDGYEMRQRQYLNPQAEFDCQGVHRMELQETR 554
                             |.||.|..||.||||||.|...|||...:|....||    ..||::..
 Frog   594 DTTEVEKCMMPECHTIPCVLSPWSEWSDCSVTCGKGTRTRQRMLKSPAELGDC----NEELKQVE 654

  Fly   555 KCSGRDCLGS---LPGSYSTDMDSPYGGASPGRIGGNMYGPQLEPEAENFGDYDDSRNGAVGGFE 616
            ||...:|..|   ...||.::.:...|       .|:|...::......||       |||....
 Frog   655 KCMLPECPISCELTEWSYWSECNKSCG-------KGHMIRTRMITMEPQFG-------GAVCPET 705

  Fly   617 VGNLKGNIGNWALNRQTNLGRDVPSLRPTNYDRARQQAEKSERTTWSGQSRPDDPRLEDVERAPW 681
            |...|..:...    |.:.|.:...|:..   |.::::||::... .|:..|      ..:..||
 Frog   706 VQRKKCRLRKC----QKSSGNERRRLKEA---REKRRSEKTKEDA-DGEQYP------VCKMKPW 756

  Fly   682 HRQRPSNKY--GSIVE 695
            .......|:  |.|.|
 Frog   757 TAWTECTKFCGGGIQE 772

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG30046	NP_725129.1	Reeler	28..167	CDD:260081	47/144 (33%)
		Spond_N	194..390	CDD:461924	79/201 (39%)
		TSP1	425..473	CDD:214559	18/52 (35%)
		TSP1_spondin	507..561	CDD:465948	23/53 (43%)
spon1	NP_001090741.1	Reeler	38..178	CDD:260081	47/144 (33%)
		Spond_N	201..395	CDD:461924	79/201 (39%)
		TSP1_spondin	439..490	CDD:465948	3/50 (6%)
		TSP_1	501..550	CDD:459668	16/48 (33%)
		TSP_1	558..606	CDD:459668	6/47 (13%)
		TSP1_spondin	611..661	CDD:465948	23/53 (43%)
		TSP1_spondin	665..716	CDD:465948	12/64 (19%)
		TSP1_spondin	751..803	CDD:480609	6/22 (27%)