Protein Alignment CG17739 and SPON2

DIOPT Version :10

• Sequence 1: NP_610757.1
• Gene: CG17739 / 36333
• FlyBaseID: FBgn0033710
• Length: 873
• Species: Drosophila melanogaster
• Sequence 2: NP_036577.2
• Gene: SPON2 / 10417
• HGNCID: 11253
• Length: 331
• Species: Homo sapiens
• Alignment Length: 304
• Identity: 106/304 - (34%)
• Similarity: 148/304 - (48%)
• Gaps: 31/304 - (10%)

  Fly   180 CCACDEAKYELTFEGKWSRHTHPKDFPANSWRTRFSDIIGASHTLDYRFWQYGELASEGLREVAE 244
            |.|...|||.:||.||||:...||.:|......::|.::||:|:.||..|:..:..|.|||:.||
Human    35 CSARALAKYSITFTGKWSQTAFPKQYPLFRPPAQWSSLLGAAHSSDYSMWRKNQYVSNGLRDFAE 99

  Fly   245 HGSTRTLESELKDQSEHIRTIIKA-RGIAYPNVTGKTFAVFRVDSNHHLISLVSMVDPSPDWIVG 308
            .|....|..|::...|.::::... ...|.|:.||:|.|...|...|.|:|.|..:.|||||.||
Human   100 RGEAWALMKEIEAAGEALQSVHAVFSAPAVPSGTGQTSAELEVQRRHSLVSFVVRIVPSPDWFVG 164

  Fly   309 VSGLELCLPNCSWVENKVHNLYPWDAGTDSGPSYMSADQPQVPPDVVRRIKSNFPNDPRSPFYDP 373
            |..|:|| ....|.|....:|||:|||||||.::.|.:...:|.|.|..|.|:.|:.|.:.||.|
Human   165 VDSLDLC-DGDRWREQAALDLYPYDAGTDSGFTFSSPNFATIPQDTVTEITSSSPSHPANSFYYP 228

  Fly   374 TGAQMKPLATLHINRRR------------LYEKNCESSDSEQVPP---ECATNSWSRWDECTTKC 423
            ....:.|:|.:.:.|.|            |..::.|..||..||.   :|..:.||.|..|...|
Human   229 RLKALPPIARVTLVRLRQSPRAFIPPAPVLPSRDNEIVDSASVPETPLDCEVSLWSSWGLCGGHC 293

  Fly   424 GP-GKQYRIREFK-NPALASRHRCNNA-----LREEKNCVGHKC 460
            |. |.:.|.|..: .||       ||.     |.||..||...|
Human   294 GRLGTKSRTRYVRVQPA-------NNGSPCPELEEEAECVPDNC 330

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17739	NP_610757.1	Reeler	23..163	CDD:260081
		Spond_N	186..380	CDD:461924	74/194 (38%)
		TSP1_spondin	487..>512	CDD:480609
		TSP1	490..541	CDD:214559
		TSP1_spondin	591..654	CDD:480609
		Kunitz-type	662..714	CDD:444694
		TSP1_spondin	733..>773	CDD:465948
		TSP1_spondin	812..862	CDD:480609
SPON2	NP_036577.2	Spond_N	41..235	CDD:461924	74/194 (38%)
		TSP1_spondin	278..330	CDD:465948	19/58 (33%)