Protein Alignment CG8850 and slc6a22.2

DIOPT Version :9

• Sequence 1: NP_725122.2
• Gene: CG8850 / 36331
• FlyBaseID: FBgn0033708
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: XP_005166102.1
• Gene: slc6a22.2 / 561024
• ZFINID: ZDB-GENE-030616-628
• Length: 608
• Species: Danio rerio
• Alignment Length: 540
• Identity: 191/540 - (35%)
• Similarity: 292/540 - (54%)
• Gaps: 33/540 - (6%)

  Fly    57 RDQWSRGVEFLFSCIALSVGLGNVWRFPFIALENGGGAFLIPYVIVLLLIGRPVYYLEVIIGQFS 121
            |:||:..:|||.:.....:|||||||||::..:||||||.:|||:.|...|.|:::||..:|||:
Zfish    28 REQWANKLEFLLAVAGHIIGLGNVWRFPYLCYKNGGGAFFVPYVLFLFTCGIPLFFLETSLGQFT 92

  Fly   122 SRGCIRAF-DMAPIMRGIAYGQVYSTALATTYYACIMALTIRYLVASFSEVLPWTYCLVEWG-KS 184
            |:|.|..: .:.|:..|:.:|..........||..|:|....||.:||:..|||..|...|. .|
Zfish    93 SQGGITCWRKICPLFEGLGFGSQVVVLYTGVYYIIILAWAFLYLFSSFTSELPWASCNNYWNTPS 157

  Fly   185 CVATGATAANDSSIVQGVSSAELFFTQTVLREPESLDDNGLGTPSWDLVLCLLATWVIIGTILSK 249
            |:....:...:.|..:..|....|:.:.:|.....::.  :|...|||.||||..|:|....:.|
Zfish   158 CMEFSESNITEYSPNKTTSPVIEFWERRILGLSGGIEQ--IGNVRWDLALCLLLAWIICYFCVWK 220

  Fly   250 GIRSSGKASYFLALFPYVIMIVLLIRAVTLPGAWQGIVYFLKPQWSQLLNPHVWYAAITQMFFSL 314
            |::|:||..||.|.|||:::||||:|.:|||||..||.::|.|..|:|.:|.||..|.:|:|:|.
Zfish   221 GVKSTGKVVYFTATFPYLMLIVLLVRGLTLPGAINGITFYLYPDPSRLKDPQVWMDAGSQIFYSY 285

  Fly   315 AICFGTLVMYASFNDFNKNVHKDVIIITTIDSLTSILAGCIIFGILGNLAFETNTKDISQVVKGG 379
            .:|.|.|....|:|.::.|.::|.:.:..::||||.:||..||.:||.:|.|... |||.|.:.|
Zfish   286 GVCTGVLTALGSYNKYDNNCYRDCVYLCLLNSLTSFVAGFAIFSVLGFMADEQGV-DISLVAESG 349

  Fly   380 AGLAFISYPEAIAKFKYLPQLFAVLFFFMLLVLGIGSNIGMASAVVNVVKDRFT------HLPHW 438
            .|||||:||.|:|... ||||:|:.||.|::.||:.|......|:|..:.|.:.      |...:
Zfish   350 PGLAFIAYPRAVALMP-LPQLWAIFFFIMIIFLGLDSEFVYQEALVTSISDMYPSFFQVGHRRKF 413

  Fly   439 LLAVSASIIGFLCGLVYMTPGGQFVLNLVDFYGCTFIALV-LAIAELLAVGWIYGVKRICSDIEF 502
            ||....| ..|..||:.:|.||.:|..|.|:|.|:.:.|: .||.:.:.|||:||..|....:|.
Zfish   414 LLLFICS-ASFFVGLLMVTEGGLYVFQLFDYYACSGMTLLTFAILQSICVGWVYGADRHYDCVED 477

  Fly   503 MLNVKTSFYWRICWAIVAPGLMFLVLVYMLFSYEPLTYRG-VQYPPVYYMAGWIIWGLGV----- 561
            |:..:...:.:.||..:.|.:.....::.|..|.||.:.. .:||       |  ||..:
Zfish   478 MIGYRPWPFMKCCWKYLTPAICTGTFIFSLVQYTPLKFNNEYEYP-------W--WGYAIGGFFT 533

  Fly   562 ----LQLPFWALVTIYQQPG 577
                |.:|.|.:..:...||
Zfish   534 LSSTLLVPLWMIYLVGTTPG 553

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8850	NP_725122.2	SLC6sbd	58..532	CDD:271359	176/482 (37%)
slc6a22.2	XP_005166102.1	SLC6sbd-TauT-like	28..565	CDD:271387	191/540 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0733
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D250396at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820