Protein Alignment CG8850 and slc6a22.2

DIOPT Version :10

• Sequence 1: NP_725122.2
• Gene: CG8850 / 36331
• FlyBaseID: FBgn0033708
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: XP_068077846.1
• Gene: slc6a22.2 / 561024
• ZFINID: ZDB-GENE-030616-628
• Length: 619
• Species: Danio rerio
• Alignment Length: 540
• Identity: 191/540 - (35%)
• Similarity: 292/540 - (54%)
• Gaps: 33/540 - (6%)

  Fly    57 RDQWSRGVEFLFSCIALSVGLGNVWRFPFIALENGGGAFLIPYVIVLLLIGRPVYYLEVIIGQFS 121
            |:||:..:|||.:.....:|||||||||::..:||||||.:|||:.|...|.|:::||..:|||:
Zfish    39 REQWANKLEFLLAVAGHIIGLGNVWRFPYLCYKNGGGAFFVPYVLFLFTCGIPLFFLETSLGQFT 103

  Fly   122 SRGCIRAF-DMAPIMRGIAYGQVYSTALATTYYACIMALTIRYLVASFSEVLPWTYCLVEWG-KS 184
            |:|.|..: .:.|:..|:.:|..........||..|:|....||.:||:..|||..|...|. .|
Zfish   104 SQGGITCWRKICPLFEGLGFGSQVVVLYTGVYYIIILAWAFLYLFSSFTSELPWASCNNYWNTPS 168

  Fly   185 CVATGATAANDSSIVQGVSSAELFFTQTVLREPESLDDNGLGTPSWDLVLCLLATWVIIGTILSK 249
            |:....:...:.|..:..|....|:.:.:|.....::.  :|...|||.||||..|:|....:.|
Zfish   169 CMEFSESNITEYSPNKTTSPVIEFWERRILGLSGGIEQ--IGNVRWDLALCLLLAWIICYFCVWK 231

  Fly   250 GIRSSGKASYFLALFPYVIMIVLLIRAVTLPGAWQGIVYFLKPQWSQLLNPHVWYAAITQMFFSL 314
            |::|:||..||.|.|||:::||||:|.:|||||..||.::|.|..|:|.:|.||..|.:|:|:|.
Zfish   232 GVKSTGKVVYFTATFPYLMLIVLLVRGLTLPGAINGITFYLYPDPSRLKDPQVWMDAGSQIFYSY 296

  Fly   315 AICFGTLVMYASFNDFNKNVHKDVIIITTIDSLTSILAGCIIFGILGNLAFETNTKDISQVVKGG 379
            .:|.|.|....|:|.::.|.::|.:.:..::||||.:||..||.:||.:|.|... |||.|.:.|
Zfish   297 GVCTGVLTALGSYNKYDNNCYRDCVYLCLLNSLTSFVAGFAIFSVLGFMADEQGV-DISLVAESG 360

  Fly   380 AGLAFISYPEAIAKFKYLPQLFAVLFFFMLLVLGIGSNIGMASAVVNVVKDRFT------HLPHW 438
            .|||||:||.|:|... ||||:|:.||.|::.||:.|......|:|..:.|.:.      |...:
Zfish   361 PGLAFIAYPRAVALMP-LPQLWAIFFFIMIIFLGLDSEFVYQEALVTSISDMYPSFFQVGHRRKF 424

  Fly   439 LLAVSASIIGFLCGLVYMTPGGQFVLNLVDFYGCTFIALV-LAIAELLAVGWIYGVKRICSDIEF 502
            ||....| ..|..||:.:|.||.:|..|.|:|.|:.:.|: .||.:.:.|||:||..|....:|.
Zfish   425 LLLFICS-ASFFVGLLMVTEGGLYVFQLFDYYACSGMTLLTFAILQSICVGWVYGADRHYDCVED 488

  Fly   503 MLNVKTSFYWRICWAIVAPGLMFLVLVYMLFSYEPLTYRG-VQYPPVYYMAGWIIWGLGV----- 561
            |:..:...:.:.||..:.|.:.....::.|..|.||.:.. .:||       |  ||..:
Zfish   489 MIGYRPWPFMKCCWKYLTPAICTGTFIFSLVQYTPLKFNNEYEYP-------W--WGYAIGGFFT 544

  Fly   562 ----LQLPFWALVTIYQQPG 577
                |.:|.|.:..:...||
Zfish   545 LSSTLLVPLWMIYLVGTTPG 564

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8850	NP_725122.2	SLC6sbd	58..532	CDD:271359	176/482 (37%)
slc6a22.2	XP_068077846.1	SLC6sbd-TauT-like	39..576	CDD:271387	191/540 (35%)