Protein Alignment CG8850 and slc6a1b

DIOPT Version :10

• Sequence 1: NP_725122.2
• Gene: CG8850 / 36331
• FlyBaseID: FBgn0033708
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: NP_001007363.1
• Gene: slc6a1b / 492490
• ZFINID: ZDB-GENE-041114-57
• Length: 600
• Species: Danio rerio
• Alignment Length: 634
• Identity: 209/634 - (32%)
• Similarity: 323/634 - (50%)
• Gaps: 81/634 - (12%)

  Fly    16 GAQGSREGH--------PGSNDGISTVIYSAEGEELTINCEAESESSGQRDQWSRGVEFLFSCIA 72
            |.:.| :||        |.:||...|::...:          :.:....|:.|....:||.||:.
Zfish     5 GTKAS-DGHVLTEVNEAPTANDKPKTLVVKVQ----------KKKELPDRETWQGKFDFLLSCVG 58

  Fly    73 LSVGLGNVWRFPFIALENGGGAFLIPYVIVLLLIGRPVYYLEVIIGQFSSRGCIRAFDMAPIMRG 137
            .::|||||||||::..:||||||||||.:.|:..|.|:::||..:||::|.|.:..:.:||:.:|
Zfish    59 YAIGLGNVWRFPYLCGKNGGGAFLIPYFLTLIFAGVPLFFLETALGQYTSIGGLGVWKLAPMFKG 123

  Fly   138 IAYGQVYSTALATTYYACIMALTIRYLVASFSEVLPWTYCLVEWGKSCVATGATAANDSSIVQGV 202
            :.......:.....||..|:|..|.||..||:..|||..|...|......:..:.||    :..:
Zfish   124 VGLAAAVLSFWLNIYYIVIIAWAIYYLYNSFTTDLPWKSCDNPWNTDKCFSNYSMAN----IGNM 184

  Fly   203 SSAELFFTQTVLREPESLDDNGLGTPS---WDLVLCLLATWVIIGTILSKGIRSSGKASYFLALF 264
            :||.:.|.:   |....|.| ||..|.   ..|.:.|...||::...:.||:..:||..||.|.:
Zfish   185 TSAVVEFWE---RNMHQLTD-GLEKPGEIRLPLAITLAIAWVLVYFCIWKGVGWTGKVVYFSATY 245

  Fly   265 PYVIMIVLLIRAVTLPGAWQGIVYFLKPQWSQLLNPHVWYAAITQMFFSLAICFGTLVMYASFND 329
            ||.::.:|.||.||||||.:||::::.|::|:|....||..|.||:|||..:..|:|:...|:|.
Zfish   246 PYFMLFILFIRGVTLPGAKEGILFYVTPEFSKLKESEVWLDAATQIFFSYGLGLGSLIALGSYNP 310

  Fly   330 FNKNVHKDVIIITTIDSLTSILAGCIIFGILGNLAFETNTKDISQVVKGGAGLAFISYPEAIAKF 394
            ||.||:||.||:..|:|.||:.||.:||.|:|.:|..|. :.|:.|...|.||||::||||:.:.
Zfish   311 FNNNVYKDSIIVCCINSFTSMFAGFVIFSIVGFMAHITK-RPIADVAASGPGLAFLAYPEAVTQL 374

  Fly   395 KYLPQLFAVLFFFMLLVLGIGSNIGMASAVVNVVKDRFTHLPHWL-------LAVSASIIGFLCG 452
            ...| |:|||||.|||:|||.|........:..:.|.|   |..|       :|| ..::.:|.|
Zfish   375 PISP-LWAVLFFSMLLMLGIDSQFCTVEGFITALVDEF---PRALRGRREIFIAV-VCLVSYLIG 434

  Fly   453 LVYMTPGGQFVLNLVDFYGCTFIALV-LAIAELLAVGWIYGVKRICSDIEFMLNVKTSFYWRICW 516
            |..:|.||.:|..|.|:|..:.:.|: |...|.:::.|.|||.:...::|.|:..|...:|::||
Zfish   435 LSNITQGGLYVFKLFDYYSASGMCLLFLVFFECVSISWFYGVNKFYGNLEEMIGYKPCIWWKLCW 499

  Fly   517 AIVAPGLMFLVLVYMLFSYEPLTYRGVQYPPVYYMAGWIIWGLGVLQLPFW--ALVTIYQQPG-- 577
            .:..|.::..|.::......|||.....:|.         ||.||    .|  ||.::...||
Zfish   500 VVFTPLIVAGVFLFSAVQMVPLTLNNYVFPK---------WGQGV----GWCMALSSMVLIPGYM 551

  Fly   578 --------KTFGSKFGLAMQPTA------NWGPLQTQK------FEAYI 606
                    .::..:..:.:||||      ..||.|..:      .||||
Zfish   552 GYMFLTLKGSYKERLRIMIQPTAAAVRTQENGPEQQPENPTPANDEAYI 600

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8850	NP_725122.2	SLC6sbd	58..532	CDD:271359	176/484 (36%)
slc6a1b	NP_001007363.1	SLC5-6-like_sbd	2..600	CDD:444915	207/632 (33%)