Protein Alignment CG8850 and slc6a15

DIOPT Version :10

• Sequence 1: NP_725122.2
• Gene: CG8850 / 36331
• FlyBaseID: FBgn0033708
• Length: 629
• Species: Drosophila melanogaster
• Sequence 2: XP_002931668.1
• Gene: slc6a15 / 100380162
• XenbaseID: XB-GENE-975885
• Length: 730
• Species: Xenopus tropicalis
• Alignment Length: 689
• Identity: 198/689 - (28%)
• Similarity: 315/689 - (45%)
• Gaps: 165/689 - (23%)

  Fly    48 EAESESSGQRDQWSRGVEFLFSCIALSVGLGNVWRFPFIALENGGGAFLIPYVIVLLLIGRPVYY 112
            |..|:...:|..|:..::::.:.:..|||||||||||::..:|||||:|:||:|:|||||.||::
 Frog    52 EEGSDIDDERPAWNSKLQYILAQVGFSVGLGNVWRFPYLCQKNGGGAYLVPYLILLLLIGIPVFF 116

  Fly   113 LEVIIGQFSSRGCIRAFD-MAPIMRGIAYGQVYSTALATTYYACIMALTIRYLVASFSEVLPWTY 176
            ||:.:||...||.|..:: ::|.|.||.:...........||..|:..::.|...||...|||..
 Frog   117 LELSVGQRIRRGSIGVWNYISPKMGGIGFASCIVCLFVALYYNVIIGWSLFYFSQSFQHPLPWDQ 181

  Fly   177 C---------LVEWGKSCVATGAT-------AAN-DSSIVQGVSSAELFFTQTVLREPESLDDNG 224
            |         .||  ..|..:.||       |.| .:||.:|
 Frog   182 CPLVKNASNTFVE--PECEKSSATTYYWYREALNISNSITEG----------------------- 221

  Fly   225 LGTPSWDLVLCLLATWVIIGTILSKGIRSSGKASYFLALFPYVIMIVLLIRAVTLPGAWQGIVYF 289
             |..:|.:.|||||.|:::...:.|||:||||..||.:|||||::...|:||:.|.|:..||.:.
 Frog   222 -GGLNWKMTLCLLAAWILVCLAMIKGIQSSGKVMYFSSLFPYVVLTCFLVRALLLNGSVDGIRHM 285

  Fly   290 LKPQWSQLLNPHVWYAAITQMFFSLAICFGTLVMYASFNDFNKNVHKDVIIITTIDSLTSILAGC 354
            ..|:...:|.|.||..|.||:||:|.:.||.::.::|:|..:.|.|.|.::::.|:..||:||..
 Frog   286 FTPKLEIMLEPKVWREAATQVFFALGLGFGGVIAFSSYNKRDNNCHFDAVLVSFINFFTSVLATL 350

  Fly   355 IIFGILGNLAFETN-------TKDISQVVK----------------------------------- 377
            ::|.:||   |:.|       :|:..::||
 Frog   351 VVFAVLG---FKANIMNENCISKNTVKIVKYLEAGNLSWSNVPHHVNFSSMSAQDYNLVYYIFQK 412

  Fly   378 ------------------------GGAGLAFISYPEAIAKFKYLPQLFAVLFFFMLLVLGIGSNI 418
                                    .|.|||||::.||:..|...| .::|:||.||:.||:||..
 Frog   413 IKEEEFDSLGLDSCQIEDELNKSVQGTGLAFIAFTEAMTHFPASP-FWSVMFFLMLVNLGLGSMF 476

  Fly   419 GMASAVVNVVKDRFTHLPHWLLAVSASIIGFLCGLVYMTPGGQFVLNLVDFYGCTFIALVLAIAE 483
            |....::..:.|.| .:....|.|...::.|..||:::...|.:.:.:.|.|..|...|::.|.|
 Frog   477 GTIEGIITPIVDTF-KVRKEPLTVGCCLLAFCIGLLFVQRSGNYFVTMFDDYSATLPLLIVVILE 540

  Fly   484 LLAVGWIYGVKRICSDIEFMLNVKTSFYWRICWAIVAPGLMFLVL----VYMLFSYEPLTYRGVQ 544
            .:|:.|:||:.:...|::.||......|:...|..::|.|:.::|    |.|.||
 Frog   541 NVAIAWVYGIDKFMDDLKDMLGFTPYKYYYYMWKYISPVLLTILLMASIVQMGFS---------- 595

  Fly   545 YPPVYYMAGWII------------WGLGV---------LQLPFWALVTIYQQPGKTFGS------ 582
             ||.||  .||.            |||.|         |.:|...:|........:.||
 Frog   596 -PPGYY--AWIAEKASEERISYPPWGLAVCISLIVFALLPVPVVFIVRTCNLIDDSTGSLASVSY 657

  Fly   583 KFGLAMQPTANWGPLQTQKFEAYIIHRKREADFKSPRGG 621
            |.|..::.|:|      .:.:|.:||.|.:::..||..|
 Frog   658 KRGKMIKETSN------LEDDASLIHEKIQSEMPSPNIG 690

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG8850	NP_725122.2	SLC6sbd	58..532	CDD:271359	166/561 (30%)
slc6a15	XP_002931668.1	SLC5-6-like_sbd	61..640	CDD:444915	182/622 (29%)