DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SkpB and skp1

DIOPT Version :9

Sequence 1:	NP_610729.1	Gene:	SkpB / 36298	FlyBaseID:	FBgn0026176	Length:	161	Species:	Drosophila melanogaster
Sequence 2:	NP_957037.1	Gene:	skp1 / 393716	ZFINID:	ZDB-GENE-040426-1707	Length:	163	Species:	Danio rerio

Alignment Length:	163	Identity:	112/163 - (68%)
Similarity:	134/163 - (82%)	Gaps:	2/163 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MPIIRLESADKEIFDTDQEIAKCSETIRIAIEDLG--DESDNSVLPLPNVNSLILKKVLHWATYH 63
            ||.|:|:|:|.|:|:.|.||||.|.||:..:||||  ||.|:..:||||||:.|||||:.|.|:|
Zfish     1 MPTIKLQSSDGEMFEVDVEIAKQSVTIKTMLEDLGMDDEGDDDPVPLPNVNAAILKKVIQWCTHH 65

  Fly    64 KDDPVVTEEVENKEKRTDDISSWDADFLKVDQGTLFELILAANYLNIQGLLDVTCKTVANMIKGK 128
            ||||...|:.||||||||||..||.:|||||||||||||||||||:|:|||||||||||||||||
Zfish    66 KDDPPPPEDDENKEKRTDDIPVWDQEFLKVDQGTLFELILAANYLDIKGLLDVTCKTVANMIKGK 130

  Fly   129 SPQAIRDTFAIQNDFLPQEEEQVRKENEWCEDK 161
            :|:.||.||.|:|||..:||.||||||:|||:|
Zfish   131 TPEEIRKTFNIKNDFTEEEEAQVRKENQWCEEK 163

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SkpB	NP_610729.1	SKP1	1..161	CDD:227528	111/161 (69%)
		Skp1	1..110	CDD:214704	73/110 (66%)
		Skp1	84..158	CDD:279768	56/73 (77%)
skp1	NP_957037.1	BTB_POZ_SKP1	3..127	CDD:349631	84/123 (68%)
skp1	NP_957037.1	Skp1	113..160	CDD:396171	34/46 (74%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170583351
Domainoid	1	1.000	82	1.000	Domainoid score	I8343
eggNOG	1	0.900	-	-		E1_COG5201
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54148
OrthoDB	1	1.010	-	-		D1412723at2759
OrthoFinder	1	1.000	-	-		FOG0000367
OrthoInspector	1	1.000	-	-		otm25944
orthoMCL	1	0.900	-	-		OOG6_100934
Panther	1	1.100	-	-	O	PTHR11165
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X346
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	13	12.720