DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SkpB and skr-20

DIOPT Version :9

Sequence 1:	NP_610729.1	Gene:	SkpB / 36298	FlyBaseID:	FBgn0026176	Length:	161	Species:	Drosophila melanogaster
Sequence 2:	NP_510192.1	Gene:	skr-20 / 181445	WormBaseID:	WBGene00004826	Length:	173	Species:	Caenorhabditis elegans

Alignment Length:	158	Identity:	45/158 - (28%)
Similarity:	84/158 - (53%)	Gaps:	17/158 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 PIIRLESADKEIFDTDQEIAKCSETIRIAIEDLG------DESDNSVLPLPNVNSLILKKVLHWA 60
            |:.:|:|.|.:||:.::...|....|.....|.|      :.:|..::|.   :|.|::.|:.|.
Worm     8 PLYKLKSEDGQIFNVERGPMKFCAFINQKFIDHGVNDRNCERADPILVPF---HSSIVQAVIEWL 69

  Fly    61 TYHKDDPVVTEEVENKEKRTDDISSWDADFLKVDQGTLFELILAANYLNIQGLLDVTCKTVANMI 125
            .:::|:|:...:   .:.|..|.|.||..|..|:.|.||.|:.|::.|.::.|:::.|...|.:|
Worm    70 YHYQDNPLARRD---SKIRYHDFSEWDKQFFNVESGVLFALLNASHALGVEDLMNMGCAAAAELI 131

  Fly   126 KGKSPQAIRDTFAIQNDFLPQEEEQVRK 153
            :|||.:.||..:.|::|     |||:.:
Worm   132 RGKSTEEIRKIYGIRSD-----EEQMEE 154

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SkpB	NP_610729.1	SKP1	1..161	CDD:227528	45/158 (28%)
		Skp1	1..110	CDD:214704	31/113 (27%)
		Skp1	84..158	CDD:279768	25/70 (36%)
skr-20	NP_510192.1	Skp1	7..116	CDD:214704	31/113 (27%)
skr-20	NP_510192.1	Skp1	90..154	CDD:279768	25/68 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160160675
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5201
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1412723at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11165
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.850